+ Reply to Thread
Page 1 of 3 123 LastLast
Results 1 to 10 of 24
  1. #1
    Join Date
    Jan 2020
    Posts
    23
    Thanks
    0
    Thanked
    9
    Reviews
    0

    Default Need some advice - Premature ovulation before egg retrieval!

    Hi Ladies,

    Sorry in advance for the longish post.

    I am new to the forum and started my IVF journey in October last year after 10 months of trying to conceive with no known fertility issues from both sides despite countless tests coming back NORMAL.

    Given I have just turned 35 and my DH is 42 we wanted to not waste time as we would like to have a family and hopefully more than one child. Additionally we felt ivf could give us more answers as to why we weren’t falling pregnant.

    I wanted some advice on anyone who has had a similar scenario occur, or could shed any light on what happened to me yesterday post egg retrieval. Below I have given some history on my two cycles to date;

    1st cycle: Rekovelle 125 + Orgalutran + 36 hour trigger
    Results: 17 follicles, 12 eggs, 7 mature, 3
    Fertilised, 1 arrested at day 4, 1 poor quality day 6 blast so we did a fresh transfer of a compacting embryo on day 5. BFN - was told might be an egg quality issue, but the classic “unsure”

    Not a great start!

    Currently in 2nd cycle: menopur 225mls + orgulatran + 38 hour trigger this time round.

    The aim was to push me further and see how I respond given the previous stim cycle was only 7-8 day, as apparently I’m a rapid responder. We also had lower than average fertilisation from our 1st cycle so my FS suggested ICSI and to stim a bit longer. All was going well and I was showing 15 follicles and around 12-13 mature follicles, the only difference in this cycle was that I had a smallish cyst and was a bit more bloated.

    I had my egg retrieval yesterday at 8am, but woke up around 4am in excruciating pain to the point I couldn’t walk. I persevered and went to the hospital for my procedure but knew deep down something was wrong given the pain I was in. I mentioned this to the nurses and specialist and they said I was probably bloated due to the follicles. To be honest I wasn’t convinced but thought they are the professionals.

    From my last scan we were hoping to get at least 12-15 eggs. When I woke up I saw 7 on my hand. I was surprised. Shortly after my FS came over and told me that when they went to retrieve the eggs from my left ovary I had already ovulated and the eggs from that side were gone, hence why I was in so much pain.

    I was in utter shock, 7 eggs lost just like that, which I was the told is extremely rare and happens in 5% of woman. Some bad luck hey? But I was perplexed by this because I felt it could of been avoided if I was monitored more closely prior to the retrieval. I had my last bloods and scan on Friday with collection being 3 days later. Is this normal? Could this have been avoided?

    I currently have 3 eggs from this cycle that were mature and fertilised so waiting to know their fate, but at this stage am completely devastated and disheartened by this cycle, as I really felt like I had a good chance, and could of had as many 6-7 other mature eggs.

    Has this happened to anyone else, and if so, is this due to negligence and lack of close monitoring of my bloods? How would you approach the clinic about this?

    I could see my FS was rather shocked, and lost for words so it made me feel a bit concerned. I came into this journey so optimistic, but after this cycle I’m feeling very low and my confidence is shot.

    I know we are all going through the same thing, and everyone’s dealing with their own hardships, so thank you for any support or advice you may have.

    Big hug to you all! This is not for faint hearted.

    X

  2. The Following User Says Thank You to Hopeful35 For This Useful Post:

    emilyc (28-01-2020)

  3. #2
    Join Date
    Oct 2019
    Posts
    178
    Thanks
    79
    Thanked
    27
    Reviews
    0
    Quote Originally Posted by Hopeful35 View Post
    Hi Ladies,

    Sorry in advance for the longish post.

    I am new to the forum and started my IVF journey in October last year after 10 months of trying to conceive with no known fertility issues from both sides despite countless tests coming back NORMAL.

    Given I have just turned 35 and my DH is 42 we wanted to not waste time as we would like to have a family and hopefully more than one child. Additionally we felt ivf could give us more answers as to why we weren’t falling pregnant.

    I wanted some advice on anyone who has had a similar scenario occur, or could shed any light on what happened to me yesterday post egg retrieval. Below I have given some history on my two cycles to date;

    1st cycle: Rekovelle 125 + Orgalutran + 36 hour trigger
    Results: 17 follicles, 12 eggs, 7 mature, 3
    Fertilised, 1 arrested at day 4, 1 poor quality day 6 blast so we did a fresh transfer of a compacting embryo on day 5. BFN - was told might be an egg quality issue, but the classic “unsure”

    Not a great start!

    Currently in 2nd cycle: menopur 225mls + orgulatran + 38 hour trigger this time round.

    The aim was to push me further and see how I respond given the previous stim cycle was only 7-8 day, as apparently I’m a rapid responder. We also had lower than average fertilisation from our 1st cycle so my FS suggested ICSI and to stim a bit longer. All was going well and I was showing 15 follicles and around 12-13 mature follicles, the only difference in this cycle was that I had a smallish cyst and was a bit more bloated.

    I had my egg retrieval yesterday at 8am, but woke up around 4am in excruciating pain to the point I couldn’t walk. I persevered and went to the hospital for my procedure but knew deep down something was wrong given the pain I was in. I mentioned this to the nurses and specialist and they said I was probably bloated due to the follicles. To be honest I wasn’t convinced but thought they are the professionals.

    From my last scan we were hoping to get at least 12-15 eggs. When I woke up I saw 7 on my hand. I was surprised. Shortly after my FS came over and told me that when they went to retrieve the eggs from my left ovary I had already ovulated and the eggs from that side were gone, hence why I was in so much pain.

    I was in utter shock, 7 eggs lost just like that, which I was the told is extremely rare and happens in 5% of woman. Some bad luck hey? But I was perplexed by this because I felt it could of been avoided if I was monitored more closely prior to the retrieval. I had my last bloods and scan on Friday with collection being 3 days later. Is this normal? Could this have been avoided?

    I currently have 3 eggs from this cycle that were mature and fertilised so waiting to know their fate, but at this stage am completely devastated and disheartened by this cycle, as I really felt like I had a good chance, and could of had as many 6-7 other mature eggs.

    Has this happened to anyone else, and if so, is this due to negligence and lack of close monitoring of my bloods? How would you approach the clinic about this?

    I could see my FS was rather shocked, and lost for words so it made me feel a bit concerned. I came into this journey so optimistic, but after this cycle I’m feeling very low and my confidence is shot.

    I know we are all going through the same thing, and everyone’s dealing with their own hardships, so thank you for any support or advice you may have.

    Big hug to you all! This is not for faint hearted.

    X
    Hi! I know how you feel about number of eggs when you were told there were more follicles at the scan! I had similar thing happen last cycle was told roughly 18 follicles but only 12 were retrieved. I was in a lot of pain that morning as well. But tbh I just didn't say anything. So I just assumed I ovulated early as well not sure why this time was so different. X

  4. #3
    Join Date
    Jan 2020
    Posts
    23
    Thanks
    0
    Thanked
    9
    Reviews
    0
    Quote Originally Posted by emilyc View Post
    Hi! I know how you feel about number of eggs when you were told there were more follicles at the scan! I had similar thing happen last cycle was told roughly 18 follicles but only 12 were retrieved. I was in a lot of pain that morning as well. But tbh I just didn't say anything. So I just assumed I ovulated early as well not sure why this time was so different. X
    Thanks Emily,

    Appreciate your response.

    I’m sorry you went through the same scenario.

    The pain was so bad, I couldn’t stand and I was not able to move for a few hours! I just am confused how my body overrode the trigger shot. Luckily one ovary didn’t ovulate but the other obviously couldn’t bear it and lost every egg.

    Did your FS mention to you that you had ovulated?

    Xo

  5. #4
    Join Date
    Oct 2019
    Posts
    178
    Thanks
    79
    Thanked
    27
    Reviews
    0
    Quote Originally Posted by Hopeful35 View Post
    Thanks Emily,

    Appreciate your response.

    I’m sorry you went through the same scenario.

    The pain was so bad, I couldn’t stand and I was not able to move for a few hours! I just am confused how my body overrode the trigger shot. Luckily one ovary didn’t ovulate but the other obviously couldn’t bear it and lost every egg.

    Did your FS mention to you that you had ovulated?

    Xo
    In all honestly I was pretty out of it when I came to it after epu. But when I saw 12 on my hand I was really confused. But something definitely happened pre epu, because I was in so much pain. And I did tell them that when I was checking in.

    I can have a look through my records later and see if they noted down anything. But I know it has happened to other people before. Someone went to go in for epu and literally ovulated an hour prior and got nothing! It is devastating, but atleast we still had some eggs collected.

    Nothing for me had really changed either...

  6. #5
    Join Date
    Jan 2020
    Posts
    23
    Thanks
    0
    Thanked
    9
    Reviews
    0
    Quote Originally Posted by emilyc View Post
    In all honestly I was pretty out of it when I came to it after epu. But when I saw 12 on my hand I was really confused. But something definitely happened pre epu, because I was in so much pain. And I did tell them that when I was checking in.

    I can have a look through my records later and see if they noted down anything. But I know it has happened to other people before. Someone went to go in for epu and literally ovulated an hour prior and got nothing! It is devastating, but atleast we still had some eggs collected.

    Nothing for me had really changed either...
    Yes, we did! I really feel for anyone who gets to egg retrieval and ovulated prior, the physical and emotional pain is so intense. I am thankful one ovary held up and I was able to get 3 mature out of the 7.

    Now just counting on these 3 mature eggs which have all fertilised to get somewhere...fingers crossed!

    We just have to keep going and persevere. Xo

  7. The Following User Says Thank You to Hopeful35 For This Useful Post:

    emilyc (29-01-2020)

  8. #6
    Join Date
    Oct 2019
    Posts
    178
    Thanks
    79
    Thanked
    27
    Reviews
    0
    Quote Originally Posted by Hopeful35 View Post
    Yes, we did! I really feel for anyone who gets to egg retrieval and ovulated prior, the physical and emotional pain is so intense. I am thankful one ovary held up and I was able to get 3 mature out of the 7.

    Now just counting on these 3 mature eggs which have all fertilised to get somewhere...fingers crossed!

    We just have to keep going and persevere. Xo
    That is it, this whole process is a hard slog. But we have to keep persevering in it.

    I have had 3 ICSI cycles now, and have only produces 1 day 6 blast. So I understand the emotional toll in it all! When is day 5 and are you doing a fresh transfer?

  9. #7
    Join Date
    Jan 2020
    Posts
    23
    Thanks
    0
    Thanked
    9
    Reviews
    0
    Quote Originally Posted by emilyc View Post
    That is it, this whole process is a hard slog. But we have to keep persevering in it.

    I have had 3 ICSI cycles now, and have only produces 1 day 6 blast. So I understand the emotional toll in it all! When is day 5 and are you doing a fresh transfer?
    Hi Emily, what are they saying about you not producing 5 day blasts? What are they saying to you generally?

    I was pushed, so they didn’t want me to do a fresh transfer, and suggested frozen this time, if I make embryos that are good enough to freeze.Last time I did a fresh on day 5, but it was compacting and had not reached blast yet. Apparently they said it looked good despite it being slow, but my FS didn’t look hopeful it would result in BFP, and it didn’t.

    Because I didn’t do ICSI in my first cycle my fertilisation rate was pretty low as we just let nature take its course. 3 out of 7 of my mature eggs fertilised so at that point I lost a bit, especially starting with 12 eggs on collection. This time we did ICSI but as you know I lost 7 or so eggs from my left ovary, so we could only work with what was left at EPU.

    At this stage I feel like my cycle 2 is a bit of a wasted cycle as we can’t really gauge what my other eggs would of done if we had actually been able to collect them.

    Xx

  10. The Following User Says Thank You to Hopeful35 For This Useful Post:

    emilyc (29-01-2020)

  11. #8
    Join Date
    Oct 2019
    Posts
    178
    Thanks
    79
    Thanked
    27
    Reviews
    0
    Quote Originally Posted by Hopeful35 View Post
    Hi Emily, what are they saying about you not producing 5 day blasts? What are they saying to you generally?

    I was pushed, so they didn’t want me to do a fresh transfer, and suggested frozen this time, if I make embryos that are good enough to freeze.Last time I did a fresh on day 5, but it was compacting and had not reached blast yet. Apparently they said it looked good despite it being slow, but my FS didn’t look hopeful it would result in BFP, and it didn’t.

    Because I didn’t do ICSI in my first cycle my fertilisation rate was pretty low as we just let nature take its course. 3 out of 7 of my mature eggs fertilised so at that point I lost a bit, especially starting with 12 eggs on collection. This time we did ICSI but as you know I lost 7 or so eggs from my left ovary, so we could only work with what was left at EPU.

    At this stage I feel like my cycle 2 is a bit of a wasted cycle as we can’t really gauge what my other eggs would of done if we had actually been able to collect them.

    Xx
    My Dr is just saying that my egg aren't great quality and I have shown signs of smooth endoplasmic reticulum in some of them. Which apparently isn't a good sign?! Which kind of sucks. I started my IVF journey in Jan last year and thinking I would be successful pretty much straight away, because I had just turned 28 and I was healthy and really thought I had nothing wrong with me. How naive was I!

    After my 2nd failed cycle, I found out I had severe hypothyroidism, been on medication for it since October last year. Requested copies of all my records beginning of this year after our 3rd cycle, and found out I have PCOS as well. We are also using frozen sperm, that was frozen prior to my partner having his testicle removed due to cancer. So we can't guarantee that the sperm is also in perfect condition. But from everything it does look like the eggs are the issues more so than the sperm though.

    I guess at this stage you can only hope that you get 1 or 2 blasts? Generally your body copes better doing a FET, due to your body being recovered from the stim cycle and it is more natural.. So I wouldn't stress about doing a FET. If you do get an embryo that isn't of good quality and can't be frozen I would be asking now if you can prep for a fresh transfer instead of frozen. Just in case, because you want to transfer it, if it can't be frozen. If that makes sense?

    Have you had any updates yet? Is today day 3? xx

  12. #9
    Join Date
    Nov 2013
    Posts
    2,837
    Thanks
    3,963
    Thanked
    2,672
    Reviews
    0
    Achievements:Topaz Star - 500 postsAmber Star - 2,000 posts
    Quote Originally Posted by Hopeful35 View Post
    Yes, we did! I really feel for anyone who gets to egg retrieval and ovulated prior, the physical and emotional pain is so intense. I am thankful one ovary held up and I was able to get 3 mature out of the 7.

    Now just counting on these 3 mature eggs which have all fertilised to get somewhere...fingers crossed!

    We just have to keep going and persevere. Xo
    This happened to me... not fun.

    I think early ovulation is just one of those things... unlucky. I think next cycle my FS started the blocker one (is it Orgalutan?) early.

    Remember, it only takes one. Good luck!

  13. #10
    Join Date
    Jan 2020
    Posts
    23
    Thanks
    0
    Thanked
    9
    Reviews
    0
    Quote Originally Posted by emilyc View Post
    My Dr is just saying that my egg aren't great quality and I have shown signs of smooth endoplasmic reticulum in some of them. Which apparently isn't a good sign?! Which kind of sucks. I started my IVF journey in Jan last year and thinking I would be successful pretty much straight away, because I had just turned 28 and I was healthy and really thought I had nothing wrong with me. How naive was I!

    After my 2nd failed cycle, I found out I had severe hypothyroidism, been on medication for it since October last year. Requested copies of all my records beginning of this year after our 3rd cycle, and found out I have PCOS as well. We are also using frozen sperm, that was frozen prior to my partner having his testicle removed due to cancer. So we can't guarantee that the sperm is also in perfect condition. But from everything it does look like the eggs are the issues more so than the sperm though.

    I guess at this stage you can only hope that you get 1 or 2 blasts? Generally your body copes better doing a FET, due to your body being recovered from the stim cycle and it is more natural.. So I wouldn't stress about doing a FET. If you do get an embryo that isn't of good quality and can't be frozen I would be asking now if you can prep for a fresh transfer instead of frozen. Just in case, because you want to transfer it, if it can't be frozen. If that makes sense?

    Have you had any updates yet? Is today day 3? xx
    Gosh, hang in there! I’m so sorry you have had a tough going, but I just want you to stay positive because you are still young, and have time! At 35 I am freaking out daily....

    We all think we are healthy hey? Funnily enough people joke constantly about me being so healthy, as I am a health freak, don’t drink a drop, smoke, eat only organic, am slim, exercise everyday, have perfect health allegedly, and the doctors kind of look at me with no explanation. Everything is allegedly NORMAL!

    Sometimes I think far out, people would be thinking how is she not pregnant yet, she is the picture of health. I understand now that it all means nothing as I walk the streets and see people that have kids and wonder how? They look so unhealthy etc....it’s crazy and cruel at the same time.

    But deep down I feel like these doctors don’t really know what’s going on and are unsure as to why I can’t conceive or didn’t produce 5 day blast or any viable embryos first go. The more I look into this IVF thing I start to realise just because your body doesn’t work perfectly with their cookie cutter protocol doesn’t mean you are a failure or unable
    to conceive. Maybe they just haven’t got your protocol right and it isn’t a one size fits all. Have hope, because I think stranger things have happened and you hear people get pregnant out of the blue all the time despite countless cycles.

    Where are you based? Which clinic are you with?

    Today is day 2, tomorrow they will call me regarding how they are going. I’m nervous, as I only have 3 to work with. They did do a polscop test on them which came back abnormal as the spindle in the egg was apparently slightly short. The scientist said to me she wouldn’t worry about that at the moment because they all Fertilised but any ABNORMAL word I hear breaks my confidence down.

    I will call the nurse today and ask about the fresh if they think viable. So are you saying they can still transfer post day 3?

    X


 

Similar Threads

  1. Need some advice.
    By Desertress in forum Pregnancy & Birth General Chat
    Replies: 2
    Last Post: 28-09-2005, 20:51
  2. need some advice on weening
    By toni in forum Breastfeeding Support
    Replies: 2
    Last Post: 22-09-2005, 12:26
  3. Older Mum needs some advice
    By FlowerPower in forum 40+ parents
    Replies: 10
    Last Post: 14-09-2005, 19:49
  4. I need some advice
    By teenmum in forum Bottlefeeding Support
    Replies: 14
    Last Post: 22-08-2005, 19:06
  5. Hi Im new & need some advice!!
    By Rooander in forum Pregnancy & Birth General Chat
    Replies: 13
    Last Post: 08-06-2005, 14:26

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts

ADVERTISEMENT

ADVERTISEMENT

FEATURED SUPPORTER
Impressionable KidsImpressionable Kids are Australia's leader in framed children's memorabilia and specialise in framed baby hand and feet ...