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  1. #61
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    I do find it peculiar that the woman mentioned in this article describes the endo scratch as an 8 out of 10 on the pain scale. I don't claim any pain tolerance titles and don't mean to be unkind....but, seriously, 8 out if 10 is a bit dramatic. This plus the fact that she was in pain for a week after as opposed to seconds or minutes for most women, I think her Dr is doing it wrong.

  2. #62
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    Hi @maxlau

    I can see you have been given some wonderful advise already.
    I am very sorry that you and your wife have had to go through this, it is just not fair is it.

    I just wanted to let you know that it took me
    5 DE transfers (all bar 1 were double embryo transfers) to get my now 1yo son. I fell pregnant with him at age 48!
    I just wanted your wife to know that so she can see she is not a failure and we are not all lucky enough for DE to just be the answer.

    I threw everything at my last transfer. I took prednisolone and clexane I had a scratch and a hysteroscopy and antibiotics just to know I had covered all bases. I also did PGS testing on my embryos so i knew they were genetically good (4 out if 8 were normal).
    Can I ask what dose of Prednisolone your wife was on previously as this is important also?
    I did fall pregnant on my third DE transfer but miscarried at around 10 weeks.
    I also wanted you to know that you can access your superannuation to pay for overseas DE if you need to.
    I agree that a UTI and endo can definately cause an embryo not to implant.
    I really hope that you have success in December and will keep my fingers crossed for you.

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  4. #63
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    Hi @Moc24, thanks for your post - I will definitely pass on to my wife, I am sure it will make her feel a little bit better.
    When we spoke to the Dr at Reprofit the other day he was adamant that there was nothing wrong with the embryos from a genetic point of view, but as we will implant the 2 frozen ones in Dec, it's probably too late to do PSG now, right?

    Re: prednisolone, you're making a good point, as the Dr asked us to find out from our previous Dr in Greece, what dosage she was on when she got pregnant through ED (which unfortunately resulted in a blighted ovum). The Dr also did not recommend for her to go on antibiotics and Clexane - can I ask you what was the thinking behind your taking both of them? Reduce inflammation I guess?

    At this stage we're looking at skipping hysteroscopy (too invasive) and do the scratch (even though there is controversy about it, as you know).

    As you've gone through a lot (like the other fab ladies in here), please feel free to recommend anything else for our last transfer. My wife has just started a new cycle of acupuncture too, forgot to say.

    Thx again.

  5. #64
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    Quote Originally Posted by maxlau View Post
    Hi @Moc24, thanks for your post - I will definitely pass on to my wife, I am sure it will make her feel a little bit better.
    When we spoke to the Dr at Reprofit the other day he was adamant that there was nothing wrong with the embryos from a genetic point of view, but as we will implant the 2 frozen ones in Dec, it's probably too late to do PSG now, right?

    Re: prednisolone, you're making a good point, as the Dr asked us to find out from our previous Dr in Greece, what dosage she was on when she got pregnant through ED (which unfortunately resulted in a blighted ovum). The Dr also did not recommend for her to go on antibiotics and Clexane - can I ask you what was the thinking behind your taking both of them? Reduce inflammation I guess?

    At this stage we're looking at skipping hysteroscopy (too invasive) and do the scratch (even though there is controversy about it, as you know).

    As you've gone through a lot (like the other fab ladies in here), please feel free to recommend anything else for our last transfer. My wife has just started a new cycle of acupuncture too, forgot to say.

    Thx again.
    I’m sorry to say it is impossible for your Dr to know if your embryos are genetically normal without doing PGS testing. The best quality embryos can have multiple chromosomal abnormalities. You can actually thaw test and refreeze but probably not worth doing for 2 embryos, but worth keeping in mind if you do need/want to do another round at some point.

    She needs to be on 20mg of prednisolone at least per day for it to be effective. I would recommend taking this just as a precaution.
    Antibiotics are to make sure you have no infection. They are neither here nor there in my opinion. Just make sure she is well at transfer time and this shouldn’t be an issue.
    Clexane is a blood thinner, older women have thicker blood. Therefore it is given to us as a preventative, blood flow to the uterus being very important during implantation and pregnancy.

    A hysteroscopy is not invasive asn can be done at the same time as a scratch/D&c ( around day 21 of prior cycle?). It is just a camera to have a look at the uterus and especially as she has endo.

    I k ow you say that you have had immune testing done but unless it was done with a specialist doctor it was probably not done properly. If I were you I would call Dr Gamel Matthius on Monday and see if you can get an appointment for proper immune testing. He can also advise on the endo and it may be worthwhile your wife taking a quick trip to Sydney for him to do a hysteroscopy.
    If you do get an appointment also book a follow up appointment for 2 weeks later to get results/protocol. He has helped a lot of women get results and in my opinion is worth seeing.

    I also looked at my successful transfer cycles (in terms of BFP as I had a few miscarriages blighted Ovum chemicals etc).
    I found that I fell pregnant on 18-19 day transfers only. I also asked for my embryos to be hatching if possible.
    My last transfer they took my embryos out of the freezer a little earlier and grew them as much as the could before transfer. One was hatching I had a singleton pregnancy!
    I have found that women tend to have better results when the embryos are hatching or fully hatched when transfered. Just an observation I have made and something worth noting.
    Also does you wife suffer from UTI’s often?
    If so this needs to be under control. I was a long term sufferer and can help you here if this is an ongoing problem.

    The fact that you have had a BFP is a good sign, a reason to continue in my opinion.
    Just tick off those other boxes and I’m am sure you will get there. Sometimes it does just take time and believe me I know how bad it is to feel like you are running out of time but I assure you, at this stage you are still well and truely in the game.

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  7. #65
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    I forgot to tell you that Dr matthias does phone covsultations Australia wide and will post you all the forms for blood tests and scripts you need.

    Also I think it is worthwhile your wife going on methylfolate or folinic acid instead of folic acid. Almost 60% of the populations bodies have trouble turning folic acid into the folate our bodies need especially during conception and pregnancy. Lack of folate causes implantation failure and miscarriage.
    This is something you can do straight away just throw out the folic acid and go buy some methylfote instead. The recommended dose is 800mcg per day.

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  9. #66
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    hi @Moc24, thank you so much for all the great advice. Would it be ok if we PM'd you to check on a couple of things that you mentioned?

    Thx :-)

  10. #67
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    Quote Originally Posted by maxlau View Post
    hi @Moc24, thank you so much for all the great advice. Would it be ok if we PM'd you to check on a couple of things that you mentioned?

    Thx :-)
    No problem at all

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