Massive perivillous fibrin deposition

[MissLeeshy]

Try saying that 5 times quickly!

I'm looking for mums who have experienced this awful disorder.. specifically mums who have gone on to have a successful, viable pregnancy following a loss due to this disorder.

A little back story.
I have 2 healthy children, from 2 textbook births following 2 uneventful pregnancies. I assumed my body was just made for easy, straightforward procreation.

Enter different daddy (maybe this is a factor.. it's also been 8 years since my youngest living child was born) and I discover that just isn't the case.

Our son was lost last June at 24 weeks to MPFD. If you haven't heard of it, it is a condition where the mother's body lays down fibrin through the placenta, causing blood clots and deposits of thick white fibrin strands. If the condition is severe enough, it causes severe growth restriction, and in many/most cases, fetal death.

It also has a high risk of recurrence in subsequent pregnancies.

So yeah.. all in all its a fairly nasty condition. It's also considered rare, and with no perinatal diagnostic methods or successful treatment plans.

Fast forward 6 months and I'm currently 7w4d pregnant. I'm on daily aspirin (150mg) and we are having a scan every fortnight to measure bub's growth. If growth starts to stall we will be looking at other options (clexane, heparin, lovenox, viagra etc) but I'm hoping the aspirin is enough.

I'd love to know whether other mums have any experience with this condition, and specifically whether anyone has had any success in being treated with aspirin alone..

Please share your story. I know pregnancy loss isn't always easy to talk about, so I absolutely appreciate anything anyone is willing to share x

[emilylouise]

Hi, not sure if it's still relevant, but yes I have had this condition and gone in to have a healthy bub with low dose aspirin treatment only. More than happy to give you more info if you like x

[Flo77]

I would love to know more about your treatment and outcome. I lost my baby at 40wks during childbirth and was diagnosed with MPFD.

[Oddsonme]

Hi, sorry this may be a bit late but I have had 2 x successful pregnancies after MPFD.
I had my daughter (live birth) via C Section at 26 weeks in 2010 and her placental pathology came back as MPFD. I was treated for MPFD in 2012 and 2017 and had two successful pregnancies to 37 weeks elective c Sections. I was treated with clexane and IVIG (intravenous immunoglobulin therapy) once a week, which generally took a whole day in hospital. Am happy to be contacted regarding any advice for treatment. I was lucky though, my treatment cost hundreds of thousands of dollars, which I didn’t have to pay for.