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  1. #991
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    Quote Originally Posted by Spazzyp View Post
    Hi olive... I have had 3 m/cs from natural pregnancies all at 6.5 weeks (got to the 8 week scan to discover they'd stopped growing at 6.5)
    I've done one round of ivf and got 2 pgd normal embies.
    Had a BFN in December from a natural FET, just received a BFP from an artificial FET... I had an intralipid infusion a week before transfer, I'm on 20mg predisalaone, 12mg progynova, 2 estrogen patches, 60mg clexane, progesterone injections and pessaries.
    Can I ask what else you were on?
    If I miscarry this one I a, definitely going to make an appointment with Dr M, is this who you saw?
    Thanks
    Hey there. Yep saw DrM. So I was on 1200mg of progesterone, neuprogen (amount depends on weight and then blood tests), dexamethasone to start and switched to 25mg of predisone at 9 weeks, intralipids every 4 weeks until 28 weeks with one IVIG at 9 weeks, 80mg clexane, then 40mg then 20mg every second day until 2 days before she was born. DH and I also did 3 x LIT treatment prior and took DHEA and melatonin 3 months prior to BFP with DH taking menevit.
    Best of luck with the pregnancy, I hope it all works out for you! Xx

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    Spazzyp  (18-03-2017)

  3. #992
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    @gorgeousgeorge. Great your local specialist will help with the infusions. 4 is an odd one without any pregnal/trigger especially at 15dpo - may well have been a sign of attempted implantation. Some reading I've done online suggests we should have our blood tests earlier to really see if implantation started--- but then that's a whole new other stress to add into the mix. Hang in there, have a consult with Dr M, for sure he WILL give you some more medications, get as much done locally with your specialist and travel to Dr M only if you have to. Best wishes X

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    gorgeousgeorge  (18-03-2017)

  5. #993
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    Thanks @Olive79 that's a heap of extra stuff! it's good to know there is another avenue to try if this one doesn't work.

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    Olive79  (18-03-2017)

  7. #994
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    Default High Natural Killer Cells #9

    Quote Originally Posted by gorgeousgeorge View Post
    Hi ladies, hoping i can join thus thread. Ive been reading it forever. Im 36 have stage 4 endo, poor egg quality and poor response to stims/low egg numbers. After 6 failed oe transfers, ive just today failed my 2nd donor egg cycle. I did 20mg pred and 40 clexane for my cycles. All the standard ivf blood tests come back fine.
    Im going to try full donor egg/donor sperm embryos next time i do ivf.
    Im wondering if anyone could answer a few question please?
    - are there immune tests that would not apply, eg the hla matches thingy, because the identity of both donors is unknown and im not coordinating testing on donor egg n sperm from overseas. So i guess are there immune tests that wont matter because its a double donation and if previous immune problems were the result of being to closely matched with my husband then they might be less likely to occur?
    -Are some of the blòod tests available cheaply in australia and can look at those before doing the pricey send overseas ones?
    - can you consult with dr m and get his advice on protocol but have another ivf fs administer and prescribe things like the intralipids and dex steriods? (sorry I'll have to learn the terms now im posting) Just because i live 800km round trip from sydney.
    -does anyone just take all the immune stuff like intralipids etc... empirically, i.e. just do it anyway even without testing?
    I have severe stage 4 endo and there is a history of auto immunity in my family. I have transferred 2 good looking own egg blasties, 4 average day 2-3 own egg embies, 2 day 3 average donor egg embies and now 2 day 5 good looking donor egg embies but all bfn. 10 embryos in total. Never gotten a positive. Tried to concieve naturally for 2 years in my early 30s still nothing with first husband. Current dh has a daughter from previous partner. Hoping moving to full donor will help if there is just some undiagnosable problem with dhs sperm. Im wanting to cover immune bases before i do that though. Just in case.
    Oh and my negative beta today came back at 4, every.other beta has come back under 2. The nurse said it looked like something tried to happen. Does she mean i finally had some attempt at implantation?
    Thanks if you are able to respond :-)
    Hi hon, I couldn't read your questions & not reply!
    Once you have a phone consult with Dr M he sends you all the pathology slips to get testing done. They're are mostly all bulk billed with the exception of a couple of them. Once he has the results you have another phone consult with him & he tells you what medications he thinks should help. He'll send you scripts (mine were emailed & I printed them out) for things like prednisolone, or Dex, clexane etc, and so the only thing you'd really need from a local doctor is intrallipids if you decided to have them. So it's all really doable.

    On that point, I've had intrallipids twice now- once I flew to Syd to have them done by Dr M, & once in Melbourne by my FS. But after reading some recent info from Dr Braverman in New York ive decided I won't do them again. I'll try to find the link to his paper- but basically the outcome was that he looked into whether intrallipids REALLY make a difference (because he's been giving them to his patients for ages). And what he found was that actually intrallipids didn't make any difference to results- but what DID make a difference was omega 3 & 6. He found that intrallipids didn't do any harm.. But didn't really improve anything. But the Omega 3 & 6 levels did make a big difference to his patients immune panel & levels of inflammation. (Basically I think what mattered was the level of both in your body.. And you want more omega 3 than 6)
    So he now advises to take 6mg of good quality fish oil daily which is what I've started doing.
    I probably haven't explained it all very well.. But I'll try and find the link to his paper so you can read it yourself. I don't have PHI so for me the intrallipids were fairly pricy due to the cost of a day bed in hospital- so having read Dr Bravermans opinion which I really respect, I decided I wouldn't bother with them now. But of course everyone has to make their own opinions on this kind of thing.

    Dr Braverman has a FB page and he is amazing in that if you ask him questions he replies within a day- I don't think he sleeps! If I were you I'd get on Dr Bravermans FB page & ask some questions.. And he'll reply. He'll probably also tell u to schedule a free 15min Skype consult with him which I've never actually done.. I'm just happy asking questions on the FB page occasionally! Don't get me wrong I think Dr M is lovely & respect his opinion too- & is the best option in Australia for the testing.. but I've found so much good information & gotten good advice from Dr Braverman on his FB page so I tend to defer towards his opinion now on immune issues.

    Am sorry about your BFN, but glad you have a plan forward X
    Last edited by Charlie74; 19-03-2017 at 11:35.

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    Faith750  (21-03-2017),gorgeousgeorge  (20-03-2017),mummanow  (20-03-2017),Peninsula Girl  (19-03-2017),Phia  (19-03-2017)

  9. #995
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    @Charlie74 thanks for that info mate, i will look into all that too xox

  10. #996
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    @ gorgeousgeorge, I'm sorry for all the trouble you are going through. I read your latest post and thought I'd share a few ideas. Have you had your endo completely excised? From what I've read on Dr Braverman's posts, endo can interfere with fertilisation and implantation. So he always recommends complete excision. He then recommends an immune protocol. But sounds like Dr M is the person to go in Aust for immune related issues. I also have endo, mild not sure what stage that was excised in Feb, so hoping this works. Otherwise going to have an immune consult with Dr M. Oh and Dr M also has probiotics and supplements for egg quality, I've tried the probiotics. Has anyone tried the supplements?

  11. #997
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    @Faith750 thank you for your message and info. Its helpful for me to get lots of ideas about what to do/try :-)

  12. #998
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    Thanks Lea7 for sharing. @pingc383 sorry to know what happened with you December cycle. Hope you are well advanced in your endeavour now. Can not send you private message as your box is full keep in touch,

  13. #999
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    Argh, a chemical for me, so plan b has to go into action.... have a consult with dr M on April 10.
    The thought of having to start from square 1 again is so hard!

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    mummanow  (04-04-2017),Phia  (31-03-2017),pops  (26-03-2017)

  15. #1000
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    Default hugs

    Quote Originally Posted by Spazzyp View Post
    Argh, a chemical for me, so plan b has to go into action.... have a consult with dr M on April 10.
    The thought of having to start from square 1 again is so hard!
    Sorry to hear that it did not work for you this time. Good on you for immediate action for next! It is hard but your resilience is admirable, which will get you there! Hugs

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    Spazzyp  (25-03-2017)


 

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