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  1. #1281
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    Quote Originally Posted by BlondeinBrisvegas View Post
    Yes Luv, this IVF business can literally consume you that's for sure!! Am glad you're in a better place now. Do you have any plans to Cycle again???

    All good here Luv with my LO and myself Thanks for the kind words r.e the separation but it was for the best. Not in a hurry to enter into another relationship either!!! Just happy to be on my own for what I envision will probably be quite a while!!!

    Yes, it's lovely to see more BFFP's and bubs being born to us more "mature" ladies!!! Am hoping this thread is on a roll!!!!
    Yes love I'm meeting with my nurse on Monday I'm going to do another oe cycle with PGD if all goes well as I'm doing embryo banking. I have 1x5day PGD normal embie on ice & 1x3day untested & plan on doing a FET in Aug/Sept. Can I please be added to the roll call that I will be doing an oe cycle in May?

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  3. #1282
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    Quote Originally Posted by Charlie74 View Post
    @skye76, I actually thought it was the opposite, that until day 3 the embryo is getting all its energy from the egg, and after that the sperm kicks in and that can be when you have problems...

    I have no idea where I got that from.. I must've read it somewhere?? So no clue as to whether it's true or not!
    @Caesardust enjoy the lavender.. What a gorgeous way to unwind! Ur DP is a sweetie!
    @infinity888.. I'm at work so have to keep it together.. But if I was at home I'd be in tears right now after reading ur post. I feel such an immense sadness, for you, for everyone one of us in here that might be in ur position one day saying 'enough'. It's really so crap And unfair that we can try sooooo hard & still not get the prize at the end. Love to you. I hope you can find some peace on whatever road you now choose to travel X

    Tx @Charlie74 I'll have a chat with my nurse on Monday & see what she says. I was going to get DH to do sperm DNA fragmentation test, as we're doing ICSI HA due to MFI (not cheap $600 oop) but I've read that there's no point doing this test if we're already doing ICSI HA another thing i will add to my list to ask my nurse on Monday

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  5. #1283
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    Quote Originally Posted by Maxwellsmum View Post
    Thanks hun. You are brilliant I also read that a few ladies take a really high dose of fish oil like 4000mg to assist with implantation. I am thinking of upping my dose if I can get past day 12.
    @Maxwellsmum can I suggest you check with Wazza before upping fish oil? I wanted to increase a few things at one point and he advised against it. Fish oil thins the blood and he'll likely have you covered for that (aspirin and clexane), so it might be too much? I accidentally ended up on 2000 and it really delayed clotting in combo with other stuff. Big difference from 1000.

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  7. #1284
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    Quote Originally Posted by infinity888 View Post
    Hi ladies. Just thought id let you all know i poas clear blue digital just now as my af is due today and it said not pregnant so im out. I know bt is 2days away but by now hcg should be at least 50 and register on cb. So thank you for all your support through our journey but it has now ended. This was our last shot and our happily ever after hasnt happened. This support group has been amazing and im really great full to have each and everyone of you. Im too sad for personals but please know you were all cherished. To everyone here who is continuing their journey i sincerely hope you all get your take home babies. As you can imagine i wont be on bh anymore after today as it will just be to painful so lots to everyone. Stay brave hopeful and strong. Take care everyone. Goodbye

    Oh, FFS's Luv, I'm so very sorry

    Sorry for the frucked-up BFN, sorry that this has to be the end of the line for you, sorry that you didn't get your take home baby

    It's just so frucking unfair!!!

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  9. #1285
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    Quote Originally Posted by Caesardust View Post
    Got the call. 2 still going but neither able to be frozen or biopsied today. 1 is a morula and 1 showing signs of degeneration. Nothing to do but wait and pray for a lot of growth in the next 24 hours. I said if something can be pgd'ed tomorrow to do it. Ladies please say a pray to the universe for me if you can today and thank you for your messages. My dp has brought me to a lavender farm for the day and the sun is shining so my anxiety levels are at bay xoxo

    They're still in the game Luv, so am and praying to the IVF Gods that they'll both pull through and be able to be frozen at the very least (but preferably biopsied please!!!)

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  11. #1286
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    Quote Originally Posted by skye76 View Post
    Yes love I'm meeting with my nurse on Monday I'm going to do another oe cycle with PGD if all goes well as I'm doing embryo banking. I have 1x5day PGD normal embie on ice & 1x3day untested & plan on doing a FET in Aug/Sept. Can I please be added to the roll call that I will be doing an oe cycle in May?

    That's great you've got 1 normal on ice if not hopefully 2!!!!


    Ok.... and prayers being sent in advance to "set the scene" for you Luv!!!

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  13. #1287
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    Quote Originally Posted by Charlie74 View Post
    @skye76, I actually thought it was the opposite, that until day 3 the embryo is getting all its energy from the egg, and after that the sperm kicks in and that can be when you have problems...
    Yes I've heard the same as Charlie, @skye76. That is why we started doing PICSI/HA-ICSI (with improved day 5 results). We talked to Wazza about it as well and he said yes it can be sperm, but egg is still a factor.

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    @infinity888 heart is broken for you today. This is the hardest and most unfair journey and you wouldn't wish it upon your worst enemy. I hope you can find happiness in your life beyond this time xoxo

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  17. #1289
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    @infinity888, I'm so so sorry. I hope you're able to eventually find some peace and happiness and you have a great life.

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  19. #1290
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    Quote Originally Posted by Gagingi View Post
    Yes I've heard the same as Charlie, @skye76. That is why we started doing PICSI/HA-ICSI (with improved day 5 results). We talked to Wazza about it as well and he said yes it can be sperm, but egg is still a factor.
    @skye76 Have heard/read the same as what the other Girls have said.

    The first couple of days it's the egg then at about the 4 cell stage, the paternal genomes kick in but Wazza is also right as the egg is still a factor as well. Anyhoo..Have found this study about Paternal Influence of Sperm DNA Integrity on Early Embryonic Development.

    Will copy and paste a little bit of it for you to read now and post the link.

    There is much debate in the literature as to whether early embryo development is influenced exclusively by the maternal factors (Braude et al., 1988) or whether there are also paternal controls at this early stage (Tesarik et al., 2004; Baltaci et al., 2006). It is well documented that the first two embryonic cell divisions are primarily controlled by the maternal genes (Braude et al., 1988) and paternal effects commence at the 4-cell stage. Further, the detrimental effects of sperm DNA damage are more prominent during the later stages of embryo development (Dar et al., 2013). The described paternal effects on pre- and post-implantation embryos include slower embryo cleavage, poor morphology, lower blastocyst formation and lower implantation rates (Parinaud et al., 1993; Janny and Menezo, 1994). However, major discrepancies exist within the published data regarding the developmental timing and the extent of paternal effects on embryo quality.

    http://www.medscape.com/viewarticle/834158

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