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  1. #1
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    Default Endometrial biopsy before IVF, to improve implantation?

    Hi ladies

    I'm about to do my second round of IVF in October. This time, the FS has a plan for me to have an endometrial biopsy after O this cycle, before getting busy with the Gonal F. Apparently this improves implantation rates in women with implantation issues. I definitely have such issues - three chemical pregnancies and one early m/c at five weeks, plus an unrelated (trisomy) m/c at nine weeks, six weeks ago. And I'm 39 so time is not on my side.

    So my question is: have any of you tried the biopsy? Apparently it's also called endometrial disrupting, and also "womb scratching" (which is a bit cutesy for my taste). Did it hurt much? And the most important question: did it work?

    I am booked to have the biopsy on the 17th.

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    Hi Roro!

    I had a biopsy immediately before this cycle and got my BFP. I am a firm believer it helped and will be discussing another one in the future when we cycle again.

    It didnt hurt at all. Like a pap smear/ET getting ready and then the actual biopsy gave me a brief cramp similar to AF. I took a couple of neurofen about 25mins before hand. I did get some cramping the day of the test, again similar to AF so I cuddled a heat pack for a bit.

    def dont be scared and good luck hun x

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    RoRo  (02-09-2013)

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    Hi Roro, I'm a firm believer of the endometrial scratch / biopsy. I Had 2 failed IVf transfers, 2 chemicals and the FS recommended the scratch to help improve implantation and then go straight into a cycle. It seemed to work as after the scratch we had our BFP on our 5th transfer. If we decide to go try for another baby I will certainly be having the scratch again. The procedure itself was just like a pap smear and worth every bit of being a little uncomfortable. I did have very small amount of spotting for a few days after the procedure. Good luck

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    RoRo  (02-09-2013)

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    Thank you butterfly and dream! I'm glad to hear that it worked for you (and that it wasn't too painful - after one EPU and two D&Cs I'm getting used to pain but it's never fun).

    Two weeks to go til my biopsy; this is the first cycle in two years that we haven't been trying, and it feels very odd to just be having sex for the fun, not for the outcome

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    Hi RoRo,

    Another big believer in the endo scratch here. My first 3 IVF transfers, all with high-grade blasts, were flat out BFNs. 4th transfer was immediately after a lap/hyst/endo biopsy and I got a chemical pregnancy- but at least there was implantation! Transfers 5 & 6 also flat out BFNs.

    I had an endo scratch done in my July cycle at 10 or 11dpo and just had transfer #7 in Aug. This time I have a much better looking BFP, BT still to come. Again I've had implantation immediately after a biopsy. That can't be a coincidence!

    The procedure itself is fine, though more uncomfortable than a pap smear for me. I took 2 Nurofen about an hour beforehand. I didn't feel the actual scratching, but the catheter they use to open the cervix is much larger than an ET catheter and it didn't tickle! It was all over in under 5 mins. I did have some spotting from then until AF showed, but no cramps or pains.

    Best of luck

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    RoRo  (02-09-2013)


 

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