Thanks blonde, it went ok, FS was pretty honest and dosent have the best hope for us. He would like dh to do the TESA procedure so we have better chance of getting better quality sperm, he mentioned the last sample from our cycle didn't look that good, also my egg quality isn't fantastic reality is setting in have another script for the dhea and he bought up about melatonin but said I could start 3mg of that CD21 before my cycle. I'm going to ask again about this u have been on it for a while? He also said he wud change my meds to Menopur 300. With the TESA that's what your hubby had done wasn't it or was it the PESA? I'm wondering whether the quality would be better day of EPU or if it's frozen it's just as good. Hubby is likely to change jobs next yr so we may have to do the frozen anyway. He also said he could put me on Testogel, giving it all we can next time. How r u going love x
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03-12-2013 15:36 #81
03-12-2013 16:33 #82
It's always a kick in the guts when we hear things that are likely to cause this whole IVF thing to be that much harder (not impossible mind you luv, just more difficult than for others)from our FS's Try not to get too disheartened luv, you haven't even come close to turning over every stone yet. You're well and truly still in the game girl, so don't give up!!!!
On the upside, at least he's willing to do a few different things such as using the Menopur next cycle at a little bit of a higher dosage than what you did last time?? The Menopur contains some LH as well as FSH (unlike Gonal-F/Puregon which are 100% pure FSH) and the thought there is maybe a little bit of LH may help with your egg quality so it won't hurt to give that a try.
That's good he's willing to let you take the Melatonin. Anywhere from 3-5mg is ok (most FS will prescribe 5mg capsules). It would be better if you could start taking it asap as it really should be taken for as close to 3 months (or more) as you possibly can to get the full benefits (same as the DHEA). I've been taking both the DHEA and the Melatonin for over 7 months now. I would probably tell your FS that I'd done some research about supplements like Melatonin and DHEA and the outcomes seemed to be best achieved when taking these supplements for at least 3 months and you'd like to try this, so you'd like to start taking the Melatonin asap yadda, yadda, yadda
Yep, my DP has had a TESA performed twice now. Last cycle I asked my FS to perform a PESA (as the sperm from the epididymis will be more mature than from the testes) first to see if there was any sperm there (as we didn't know for sure where my DP's blockage was at the time), but unfortunately, no sperm was found, so it was back to the TESA for us (which got plenty...enough to freeze 2 vials one of which we'll be thawing and using this cycle). Make sure you get your DH onto those supplements I posted for the men. I made my DP take them for the 3 months before our last cycle, and one of our embryologists told me the quality of DP's sperm was even slightly better than the first lot of sperm he had TESA'd in Cycle 1 when he hadn't taken any supplements etc at all (because I knew nothing then, was a naïve "deer in the headlights" first time IVF'er still in shock at DP's diagnosis and still trying to get my head around the fact we'd have to do IVF if we wanted a baby).
As to the quality, it probably would be better on the day as fresh is usually best, but I know that my DP's sperm thawed out with no problems and the quality was just as good (used thawed TESA sperm on Cycles 2 and 3). Sperm usually doesn't have too much of an issue thawing out luv, so it shouldn't be a drama if you need to use it next time. If you're unsure, you could always talk to an Embryologist at the lab your fertility centre uses??
The testogel is used for a similar purpose as the DHEA and some women have had a marked improvement with egg quality/embryo quality because of it, so something to think about too. Did your FS mention anything about Human Growth Hormone (Saizen/Omnitrope)??? Could be worth a discussion, but it is expensive just so you know.
I'm going well luv Day 4 of stimms and am handling things physically, mentally and emotionally a lot better this time around than last time (which I think is a combination of lower dose stimms, all the vitamins and supplements I've been taking for over 6 months plus the regular massage and almost daily meditation I'm doing), mind you, it's early days yet and we'll see if I'm still singing this song by Sat!!! Am due to see my FS on Fri for scan/bt's, so will see what the go is then. Of course I'm hoping to see lots of lovely follies growing Usually my right ovary does most of the work, so expect to see most of the action over that side. Usually it's 3-4 on my left, but am hoping to see an improvement this time around. Will let you know how I go.
So when are you likely to cycle again luv and when are you due to see your FS again?? Did you talk to him about 3DT's??? You've got a bit to think about, but I'm glad to see your FS has had a think about things and is willing to adopt new approaches/drug protocols. That's always a good sign.
Ok sweetie, thanks for popping in and letting me know how you got on. Will do the same on Fri when I've had my appointment. If there's anything else I can help you with, just ask away luv and I'll do my best. Until next time..................
Last edited by BlondeinBrisvegas; 03-12-2013 at 16:37.
03-12-2013 22:56 #83
For my last 2 cycles I was on Puregon, last time 250 for most of the cycle. I'll call them tomorrow or email and confirm if I can start the Melatonin now. It's annoying there are always questions that come up after a visit, I always write things down to try and remember everything but always something is forgotten. I'll also check about the fresh versus frozen sperm. With the Testogel I remember them bringing it up last time however they said u can either be on the dhea or that, they also said Testogel has affects after about a month. Glad to hear u r going ok, massage sounds good, I miss acupuncture, I was mainly going during my cycle but I'll start back up in the new yr. all of this costs $$ so can't do everything. We prob won't cycle till around Feb/Mar, I regret in a way I pushed to do 2nd cycle when I did, I should have waited till I was on the dhea 3 mths, at that stage it was around 2. Can't go anything now, I guess we all have some regrets. Thank u for being so supportive, I hope lots of blessings come your way x
04-12-2013 05:18 #84
It always seems to be the way that you think you've covered every query you have with your FS, only to leave the appointment with even more questions in your mind Just keep writing them down and maybe correspond via e-mail with your clinic until your next appointment??
Although I've never tried the testogel, I've heard doing the testogel and DHEA at the same time could be a bit of overload, so maybe just go with the DHEA for now and put the testogel on the backburner (hopefully you won't need it). Although, maybe there is a way to combine the two???
I wanted to try acupuncture this cycle, but our funds just wouldn't stretch to it, so went with the massage/meditation instead. Oh yeah, this costs $$ allright and both my DP and I don't earn a hell of a lot of it, being "blue collar" workers (and me only working casual as well), so understand where you're coming from there (I suspect most of us BH's do). It also doesn't help when your clinic put up their prices for a cycle either, which is what I found yesterday when I got the invoice for this cycle...that it's gone up $500 since the last one 6 months ago!!! For what is what I want to know??? F*cking nothing is the answer!! Because they can and they know they have us over a barrel and it's either pay up or you won't have a chance at having a family. Really pi$$es me off!!!
Yes, I think we all have some regrets or things we wished we'd done differently. But it's all a learning curve for us and you now know to listen to your intuition when it comes to things like doing another cycle. Plus when you first start, it can be very intimidating, and we tend to put our blind faith and trust in our FS's because we don't know any different and usually we're also still dealing with the fact we've ended up in his/her office in the first place. Unfortunately, it's only experience that makes us wiser to everything and strong enough to sometimes challenge our FS's on things such as when to do another cycle, what drug protocol to use and at what dosages, when to transfer our emby's and how many etc,etc. So don't be too hard on yourself luv. What's done is done, and its best to just deal with the here and now (because that's all you do have control over) and a little to the future (seeing what's ahead not only motivates us, but keeps us on track and headed in the right direction) and before you know it, it'll be time for you to cycle again
Thanks again for all your well wishes and support. I wish all the luck and blessings in the world for you too girl. Be back with an update on Fri. Take care sweetie. Until next time.................
06-12-2013 20:04 #85
I emailed them the other day they need to get back to me once they have spoken to FS about the TESA. he is only in a few days a week. I questioned about the melatonin and they said it can't hurt to start earlier. I really wonder sometimes, if I didn't have this forum or other sites there would b things I would just go along with putting complete trust in them. They should b telling me to take it ASAP when I saw him the other day. I noticed a price increase sign on the wall too - sigh how did u go today? Oh forgot to say I did ask whether I cud do a 3dt next time if we have some healthy embies, he said he wud if we really wanted to but didn't encourage it saying it gives us false hope
07-12-2013 05:07 #86
Exactly luv!! I think regarding IVF, knowledge is power, and most people would just go along with what they say and most FS will just keep on trotting the same protocols out time and again, not willing to change/try anything new (which makes me question is it about your best interest or $$$$???......my jaded/cynical side coming out!!!). I'll be interested to hear what their opinion is regarding the fresh/frozen TESA. I swear my FC increase their prices every 6 months!!
Good to hear you're starting the Melatonin asap and good on you for having the courage to question it and about doing the 3dt's. Fair enough if your FS doesn't support it, that his opinion, he's entitled to it (mine doesn't either for the record), but you're also entitled to have a transfer of whatever day you please if you ask me and your FS should facilitate that regardless of what he believes (which is what mine does). Yes, it's important to listen to their recommendations, but I do feel that the choice should come down to the individual/couple.
AFM: Had a bit of a turbulent 24hrs from Thu-Fri. Received a letter in the mail from my FS with a copy of some BT's I had done on the day of my Endometrial Scratch showing my Prolactin levels majorly elevated (which can be caused by certain factors...pregnancy/breast feeding,stress, medications or a tumour on the pituitary gland). Of course, I go into panic mode running through the possible ramifications to this cycle, my eggs, the embryo's (will my body reject them because it already thinks its pregnant??? will I have to cancel the cycle now??? blah,blah.blah). He was quick to assure me that there would be no adverse affect on the cycle, my eggs or the embryo's and that the effects of abnormally high Prolactin levels result in the prevention of ovulation and your periods stopping etc and since we were controlling ovulation, it wasn't an issue.
Had a sleepless night and went to my CD8 appointment yesterday and once my FS ruled out medication/stress as the cause, he organised a referral for an urgent MRI on my pituitary gland and repeated the levels with my other BT's as well.
I had the MRI early yesterday arvo and while I was waiting for the x-ray's to be developed, I called the clinic for the blood test results and lo and behold, my Prolactin levels are back in the normal ranges again!!! WTF??? My FS got on the ph and told me he doesn't know why this has happened but he's seen it happen with other ladies (not often,mind you) where their levels spike for an unexplained reason and then go back to normal, or he's seen ladies where their levels go up and down "like a yo-yo" again, for no apparent reason.
Anyhoo, he also gave me a script for some medication to take to lower the levels and wants me to keep taking the meds for now as a preventative, just in case I'm one of those women who's levels "go up and down like a yo-yo" as he said, as the medication is safe to use in pregnancy (as if he'd prescribe it otherwise) and it can do no harm to take it just to be on the safe side.
I won't know the outcome from the MRI until Monday when I see my FS again as the report was sent to him and wasn't in the envelope my scans came in.....bugger!! but now that my levels are normal again, it seems less likely there will be a tumour there and I probably wasted $400 for someone to tell me there's nothing wrong with my brain after all!!!! No, I'll be grateful if all is well and at least I'll have the peace of mind of knowing for sure that there's no tumour.
Other than that, an on a brighter note, I have 9 follies (5 on my right and 4 on my left ovary) on the go atm (though I don't really see that changing at this stage), the largest one was at 14mm yesterday, so he's upped my FSH from 300IU to 400IU as of yesterday and the rest of my BT's are on track (though I felt my E2 levels were a bit low for the amount of follicles I have, but that may be due to the fact the biggest one is only at 14mm's).
I'm to have another BT in the morning to check all levels and then back to see him on Monday for another scan/BT. It looks like EPU will be around Wed/Thu next week, so getting closer now I'm just hoping we can capture all 9 follicles and that they will all contain a lovely, mature egg Last cycle I only got 7, so am doing better on that score this time around thus far.
Ok luv, thanks for checking in and checking up on me. Be back for an update after I see my FS on Monday. Again, good on you for getting on to them at your clinic, and getting things happening!!! Never be afraid to speak your mind luv....if you don't ask, you don't get and that's especially true in IVF. Most of the time we have to suggest things to our FS's to do or use etc as for some reason, they won't do it themselves, though they all seem to have the knowledge when you do ask them about it?????
Have a good weekend Booboo and let me know when you hear back about the TESA enquiry....Until next time...................
Last edited by BlondeinBrisvegas; 07-12-2013 at 05:10.
07-12-2013 22:06 #87
Crap sorry to hear u have had a rough few days must have worried u so much, glad to hear things r getting sorted out, this is extra stress u don't need. Yay that's great about your nos hope u see them growing nicely on Monday. Thanks yes I'm not worried anymore, paying so much money have a right to question things. Hope u r having a nice w/e, not long till EPU for u Read u should take the melatonin at night, did u find it helped u sleep? So being on Melatonin/dhea/coq10 I hope all of this helps, all these meds r expensive but worth a go, giving it all we can this next time
Last edited by Booboo78; 07-12-2013 at 22:16.
08-12-2013 05:08 #88
Yes, I take the Melatonin at night about an hr before I want to go to sleep. It knock's me clean out more often than not every night!!! The supplements are expensive that's for sure, but definitely worth a go and unfortunately, you just won't know for sure if they have helped until you do your next cycle and then you'll be looking at a) egg no's, b) eqq quality and c) fertilisation/embryo quality.
Of course, you're only one half of the equation and your DH's swimmers have got to be in the best shape possible they can be in too, that's why its important he takes his supplements as well. Then we all keep our we get the right egg/sperm combo and form a healthy embryo. And I totally agree with you regarding having the right to question things. The majority of us pay a small fortune to do this and as far as I'm concerned, the onus is on the FS and the FC to make sure we're satisfied at the end of the day or else I for one, will and have taken my business elsewhere
AFM...........Am off for another BT this morning then back to see FS tomorrow for an update. I'm really hoping my E2 levels have picked up since Fri as I do feel they were a bit low. Am feeling much calmer now that I know my Prolactin levels are back in the normal ranges, but it was a major stress that I didn't need and am looking forward to finding out the results of the MRI tomorrow as well.
Am having a good weekend so far. Helped sort out my sisters plants that she wants moved from the old house to the new one next weekend. Well, to be accurate, my DP did He's the "garden guru" in the family and I'm just his offsider!!! Anyhoo, most of it's done, one or two others that need to be sorted towards the end of this week, so all good there.
I think today will be pretty laid back. I'm starting to feel the bloating/fluid retention building, plus the meds my FS put me on to lower my Prolactin levels make me feel nauseous and a bit light headed, so don't want to be doing too much besides the usual "domestic drudgery" around here that I do on a Sunday. I might try to book a sneaky massage before EPU if I can though!!!
Ok girl, must go for now. Hope you and your DH have had a lovely weekend too. Take care and I'll be back for an update after I see my FS tomorrow. Until then...........
09-12-2013 11:27 #89
Just dropping in to let you know all went well with my FS this morning. My MRI scan came back normal, so no tumour and I've still got all 9 follicles on the go as well. They're all measuring pretty evenly, and are all within a couple of mm's of each other with the lead follicle at 20mm's I think.
My BT results are all fine according to my FS, although I'm concerned my E2 levels are a bit low in relation to the number of follicles I have, but he wasn't worried when I pointed out my concerns to him. Will see later on where the levels are when I ph up for today's blood test results. My lining is at around 9mm's which is slightly less than last cycle, but is still ok I think and it should thicken up a little bit by the time I get to ET (all going well of course).
So EPU is booked for this Wed (am triggering with 10,000 units of Pregnyl, same as last cycle) and I'm having an Intrallipid Infusion after EPU as well. I'm having that done as a preventative, as my FS said it won't hurt to cover all bases "just in case there are any immune issues we don't know about" (but which he doubts, and so do I. Been tested for just about everything you can think of anyhoo). And, again, all going well, will have a Day 5 transfer. So, now we and hope for the best
Ok luv, just wanted to fill you in. Hope you had a lovely weekend and are having a great day too. Until next time.................
09-12-2013 15:12 #90
Hi glad to hear all is going ok, your nearly there have never heard of that infusion before. Hope u get some beautiful embies x With the Melatonin it's def helping me sleep, it's great I'm still hearing mixed reports about when to start it though, a few others said its enough to b on for just 28 days
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