Just curious about this as I have been taking it since the start of my IVF cycle, I am on 10mg but will go up to 20mg after egg collection.
I have read some conflicting stories about it online...anyone had any experiences with this at all?
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12-10-2012 12:07 #1
Can prednisone affect egg quality?
13-10-2012 13:36 #2
Hi - I just did my 3rd stim cycle, but the first one of high dose prednisolone for immune issues (25mg/day from CD1). I got a similar number of eggs as I did on previous cycles, however my fertilisation rate was much lower (less than 50%, where I normally get close to 100%). The scientist said it looked as though there was a structural problem with about half the eggs they collected so when they ICSIed them they didn't fert. I hadn't thought to link that to the steroids but your post got me thinking. I'll be asking my RI when I see him next.
13-10-2012 15:24 #3
Wow, that is really interesting. I am sorry you didnt get as good a fert rate as previous cycles. I am really worried about that happening with me, both my IVFs we have only ever had four out of the lot make it to blast stage.
It will be interesting come EPU time to see what happens....
May I ask what else you did with your protocol? I have been on cetrotide days 1-3, then 125iu of gonal f till day 10 when I saw my FS and he upped it to 150iu. I have a lot of eggs but they arent quiet the right size yet.
Go back on Monday and hoping to trigger with synarel then
Good luck with your ET, I hope you get some frosties too!!
13-10-2012 15:35 #4Senior Member
- Join Date
- Sep 2008
- Adelaide SA
I had prednisolone throughout 1 stim cycle & 6 FET's. On my stim cycle I got 25 mature eggs, 24 fertilised, 2 transferred at blast stage and 6 frozen. For my last 2 FET cycles I was on 30mg & I now have a 14 month old DD.
Good luck on your journey
13-10-2012 16:04 #5
Hi Hoping. Thank you for your positive experience! Makes me a little more relaxed about it
Congrats on your precious little miracle
15-10-2012 08:18 #6
Hi there bub4mepls, I was on 20mg prednisone (plus aspirin) both for the EPU and the and the frozen cycle that gave me my beautiful baby boy Thomas - healthy and perfect in every way. I hope this cycle is the one that brings you your baby ...
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