Just heard from the lab. Out of 13, 9 have fertilised made it through to the next stage. 4 were immatured and didnt make it .
Is that good? Boy this is one big rollercoaster.
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31-07-2012 11:46 #1501Junior Member
- Join Date
- Jun 2012
I think its Yay??
31-07-2012 11:57 #1502
31-07-2012 12:09 #1503Senior Member
- Join Date
- Nov 2011
I had the exact same thing happen in my last stim cycle (which was also my first). I had 20 eggs, beautiful, apparently good sperm and zero fertilisation. They just don't like each other. Was a shock to FS, FN, scientist and us! FS had originally suggested ICSI for us but I had said no because we were unexplained and I wanted some sort of natural selection. I have now got over that 7 weeks later and we are doing ICSI.
It was a blow for us and I was forced to have a cycle off which I personally feel was great as I didn't feel too affected by the drugs, but a cycle off made me realise I was more affected than I thought. By some miracle I fell pregnant naturally in that off cycle but lost it at 5 weeks and wonder if all the stim drugs did something to help that happen, who knows? (I mean get the bfp, not the mc).
I have been allowed to start stimming again straight away after mc (if that's what you call it at that stage) and am just eager to get on with it and go again. I am looking at the positives in the first part, I am a decent responder to the stimulation and the side effects are minimal and I recover from EPU well. I also didn't have to use the crinone as there was no transfer and I don't know why I am so irrationally paranoid about the crinone. And as it turns out I can get a blasty and implantation naturally (as you have), so I'm thinking that's a good sign too.
I can't help but look to the end goal at this point. The stimulation is a means to an end and fingers crossed it works for us both next time. It's no consolation at this point for you though, I can say from experience it does look brighter now I'm starting again. I will be petrified day after EPU and THAT phone all
Last edited by wunsi; 31-07-2012 at 12:11.
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31-07-2012 13:22 #1504
Just quickly: Lynlee, so sorry hun. That totally sucks. Especially after such a great EPU result. Hopefully ICSI is the key for you guys. I still think it's weird that they didn't say anything about your DH's morphology. The embryologist told me that the reason my DH's frozen stuff didn't work last time is because the morphology of the entire sample was so bad, so it is definitely a factor. But maybe the info was incorret the first time?
Hope that the next month or two fly for you so you can try again.
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31-07-2012 14:06 #1505
Sending big hugs to all those struggling today. I've been in a constant state of disappoinment this cycle, with today's news being the only exception. I hate that this isn't easier, or smoother, for all of us.
I'm still in a bit of pain from yesterday's EPU. Hurts after I use the bathroom (sorry, TMI) - just this horrible pressure, and I feel like I can't tense up my tummy. No bleeding though, unlike last time. I'm scheduled to go back to work tomorrow, so I'm hoping all is ok for then.
I don't want to touch the Roll Call, since it looks a bit wonky again, but if anyone wants to move me, I'm scheduled for EPU on August 4th. Gosh, I hope they make it that far.
31-07-2012 14:10 #1506
My computer died last week and I had it in getting fixed. Finally got it back today!!
There is just wayyyyy too much to catch up on to do personals, so I am going to send to those that need it, and to those that need it
AFM - I found out that I actually don't have a frozen day 3. I have 1 frozen from my first cycle, and 1 frozen from my last cycle
I had my first scan yesterday on CD13 and my lining is at 10mm, so I have ET next Monday. Is that too far away? Waiting another week for transfer seems like a long time. I don't want my lining to go too thin or thick or anything because I'm still taking the progynova.
Still worried if either of my frosties are going to thaw. We will be putting both back if they both thaw. I really hope they do, and I really hope both take and I get twins because I really don't know if I could go through all of this again for a second child. Maybe I shouldn't think like that. I mean, I can't even get 1, yet I am hoping to get 2 in 1!!!
31-07-2012 14:23 #1507Senior Member
- Join Date
- Feb 2010
Lynlee, I'm so sorry. I hope you can get over the pain of the disappointment.
We luckily are still in the game. As both eggs did fertilise and split to two cells. She'll check them again as they developed very quickly but she's hoping they will last to say three or day five transfer.
31-07-2012 14:35 #1508Senior Member
- Join Date
- May 2012
Quick one from me too. Ive been having a rough time, so quietly observing from the back blocks.
Wunsi - there is good and bad in your story, mostly good I reckon. Good luck with the next bit!
POH - 13 is a great haul (depending on your age really). Something like 7 eggs is the norm for someone who is mid 30s. 4 being immature is fine too. Truth is not all eggs are good and not all are bad. And, not all will make it to blast either. Something like 30-65% will make it to blast. Good luck, you have good numbers to work with.
Lynlee - I can imagine your pain. All I can do is give you a big hug
My apologies upfront if its not appropriate to say this right now and you arent an information seeker like me! a
But, sometimes the FS gets the protocol slightly off and that makes a big difference. Im not sure how many cycles you have done, but my experience is that the first one is often just a complete science experiement for everyone involved (and a horrible emotional one for us) and even subsequent cycles are about changing some things to see what effects they have.
With IVF/ICSI its always a balance between quantity and quality. The cycle before my last one we got 12 eggs, 10 mature and 5 still going strong on day 3. Then it all went to sh*t. We used DHs fresh sperm on that go - and we had TWO (yes 2!) motile ones in there. So as Sariele says sperm motility and morphology do matter. To some extent ICSI overcomes this, but the quality of the eggs and the sperm still matter even with ICSI. Otherwise we would all get pregnant and have babies from each fabbo blast. Also, my big egg haul cycle my eggs were a bit weird too, and it was hard to remove the cells surrounding them for the ICSI. Now you wont have had that done with IVF, as they expect the sperm to get through that naturally. But we overcame that issue too with sacrificing some numbers on the last cycle to get better eggs - and that worked much better. This is where the skills of the FS and their experience are crucial. Just FYI second cycle got 6, 6 from 6 fertilized with frozen testicular sperm (which is pretty much the worst sperm there is) and 5 made blast, one went wonky, two transferred (unfortunately they were our missed miscarriage of identical twins) and two on ice. So it can happen. Its a numbers game Im afraid. This cycle the numbers werent in your favour, but next time, they will be Im sure. And you have got there before. (May I also suggest maybe some other testing on DHs sperm - say sperm fragmentation testing and perhaps a look at antibodies etc). There are some people who have incompatible sperm and eggs, but ICSI will help with that!
And I can tell you that I wanted to throw it all in after each of our failed cycles but as Clem says we are a special breed us IVFers!
(Being more ****ed off that upset is also totally normal for right now! )
LuckyMe - hang in there hun. Im very sorry it hasnt gone to plan so far. But while you have two in the race there is still a chance!
LKeith - your poor friend. Im finding it hard enough dealing with our early loss of twins, I cant even imagine losing one that late and then another one early just after. I do have a friend who had a 39 week still birth and it was awful, but she has two beautiful boys now and one she remembers very fondly and actively every day.
Disney baby - goodluck!
Clem and GirlX -
Can I please also be added to limboland, if it is ok to still keep posting while Im a few weeks off starting cycle 5! (OMFG cycle 5, how did that even happen )
The Following User Says Thank You to SelM22 For This Useful Post:
31-07-2012 15:30 #1509
Hope everyone is well and your cycles are progressing superbly.
I just had a quick question....I had EPU on Friday and the doctor said that my ovaries were the size of grapefruits (no exageration) when they should really be plum size.
I was really sore after EPU but felt better the next day and have slowly gotten better and my weight has been dropping not increasing. I have been drinking MASSES of fluids to try to avoid any chance of OHSS but I was just wondering if anyone else has had really enlarged ovaries like me and also whether they found that when their bladder was full it became really painful, like it puts pressure on the ovaries?
Also, how long does it take for the ovaries to go back to normal size?
Thanks in advance
31-07-2012 15:34 #1510Member
- Join Date
- May 2012
Thanks girls for all your lovely words and advice.. I will definitely be questioning the fertility specialist about hubbys sperm morphology next time, and i have some notes from things i read today about sperm anti bodies, but ill also ask about fragmentation... they did say like someone mentioned about - his sperm and my eggs just dont like each other!! God knows how me managed to conceive our son
Im feeling better now after a good few hours of crying and feeling sorry for myself... but get this girls (you will all understand - hubby didnt quite)...
I wrote on facebook about not realising until today just how much of a miracle our son is..... then 5 minutes later this other girl (wouldnt call her a friend really anymore) who always see's the need to compete and boast about her son, wrote something about wishing her "miracle" son a happy 6 months... it was literally within 5 minutes of me writing it... it really got to me, her son was conceived within 2 weeks of meeting her new boyfriend and was an unplanned pregnancy!! grrr how is that a miracle?? yes i know all babies are a miracle in some ways, but jesus, that baby's conception was nothing short of 100% natural, and i suppose you could say - perfect!! i just thought that was a real kick in the guts as she knows we are going through ivf!
maybe im over reacting!!
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