Hi Dr Sterling,
My husband and I have been trying to conceive for 6 years now. I am 32 and he is 37. We have known about his low sperm count since 2007 and first tried natural therapies & healthier lifestyle to improve the numbers. We did get them to increase from 0.4million/mL up to 5 million/mL and started ICSI in Jul this year. Fresh embryo transfer in July didn't work, nor did frozen transfer in Aug. We still have 4 frozen blastocysts. We were told that all 6 of our blastocysts were top notch and had a good chance of implanting.
Up to now, the focus has always been on my DH as the reason for our infertility. My tests always came back as being perfect, I don't drink or smoke and my BMI is 22. However, after our second failed cycle I requested more testing for myself, simply because I don't want to use up all our embryos, only to find out at the end that there is something wrong with me too.
Through these extra tests, we have discovered that I have elevated thyroid antibodies yet normal TSH, T3 & T4. The antithyroglobulin was normal, but thyroid peroxidase was over 1000 (normal limits 0-35).
My FS said that because TSH, T3 and T4 are normal, that I don't need any treatment and that the high antibodies have no impact on my ability to fall pregnant.
We are about to undergo our 3rd cycle, this time transferring 2 of our remaining 4 frosties. I am concerned that I should be taking prednisolone to counter-act the antibodies and that I will continue to have failed cycles if left untreated.
Do you agree with my FS that the antibodies are irrelevant? Should I seek advice from an endocrinologist?
Thank you in advance for your help!
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27-10-2010 10:20 #1
Thyroid Antibodies and IVF
27-10-2010 16:13 #2Appointed Bub Hub Online Expert
- Join Date
- Sep 2010
I would discuss your concerns with your specialist and ask if a review would be helpful from an endocrinologist. This way all parties will be happy before further transfers. Good Luck GS
27-10-2010 17:12 #3
I was going to revisit the topic with my FS, but had hoped for a second opinion from a credible source! When I produced the list of advanced infertility testing that I wanted, I got the speech about how google is the specialists worst nightmare...
I have found a number of journal articles, plus info from my naturopath that links high TPO with infertility, miscarriage & premature labour. So I'll just arm myself with those and see how I go.
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