hello ladies - this is my first ever post but have been reading forums on bub hub for over 12 months now - I saw this thread today & had to contribute...hope I am ok to post my story here - if not, please let me know if I should move it (i have tried to trim down the story as could go on for ages!)
me (32) & DH (35) have been TTC since June 2010 - went to GP in Sept 2011 - DH went for sperm analysis & azoospermia was diagnosed...GP referred us to fertility specialist in Sydney & we saw Dr Gee @ Genea - she then sent us both for loads more tests - me for ultrasounds & blood tests & DH for blood tests, retrograde sperm test (to see if sperm goes back into bladder) & also ultrasound - she also had a 'feel' on our first visit & said his testes were small & soft so she thought there was a production problem rather than a blockage...got results back & we were devastated - she basically said he had no sperm & thought there was a low chance of finding any but that the only option now was for him to have a biopsy (my results were ok). We spent about 4-5 weeks in between these appointments just feeling crushed - we had so many plans, hopes & dreams & now it seemed like we would not be able to have our own children. We ruled out donor sperm & decided if it was not to be for us then we would look into adoption. Dr Gee referred us to Dr Lok as said he was the expert in biopsies etc. we saw Dr Lok early Dec & he also had a 'feel' and came to the same conclusion - said maybe 40% chance of finding sperm if we are lucky. Me & DH had big deep & meaningfuls over it - he said he did not want to go through with biopsy at one point as his heart was already broken & he couldn't bear to feel any lower - but he also said he needs to know for sure. So it had the biopsy done mid Dec - Dr Lok came back in, slapped him on the back & went 'we found sperm, we found sperm!' - we were both absolutely stunned - it was not the answer we were expecting at all & he even said he had managed to freeze two 'straws' or vials. He said it was a really positive result - he only had to go in one side too. He is now happy for us to go ahead with ICSI but he said he does not know how the speem will thaw & he does not want to do a test one as he did not get much. We have just moved states so once settled, we will be going ahead with this in a few months.
We seem to be on a similar journey so I look forward to hearing about how you go with your appt tomorrow.
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12-01-2012 20:36 #111Junior Member
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- Oct 2011
14-01-2012 08:02 #112
Hi red79 - welcome! Thanks for sharing your story; that's so great that you found sperm!
Well, yesterday was good. Although my DH is something of an enigma, Dr Golovsky said. Physically and genetically, there is nothing wrong with him, which Dr G found curious. Said his testes were totally normal, testosterone and FSH levels normal, no chromosome microdeletions - so nothing else to indicate why Sertoli-cell only Syndrome. But anyway he's going to do the microdissection - no guarantees, but massive fingers crossed .
It is obviously better to time it with a cycle for me, so they can do ICSI straight away if they find any. The procedure actually IS expensive though. We have PHI but it doesn't cover us for IVF or infertility investigations yet (we upgraded but you have to wait 12 months). So between Dr G's fee, the anaesthetist's fee (which is way above the scheduled fee - so you were lucky felicita!), day surgery fee, scientist, etc, it adds up to about $4k just for that, not even including the IVF cycle. But we'll definitely do it - we'll always wonder if we don't!
So they took blood from me to re-test my thyroid, as that was the only thing from all my earlier tests that wasn't a-ok. And we have an appointment with one of the fertility specialists on Wed morning! Eeeek - here we go!
14-01-2012 18:52 #113
Hi all - we do ivf for mfi reasons. Late Feb we will be booking on for our 11th cycle! Just wanted to confirm what you say about fertility first - yes they have donor sperm (almost all from USA but also some from Aus) available. We have been at the point of using it twice but then they manage to find a few sperm. You just need to do the counseling first but I don't think they have a six month wait to qualify (but that could be wrong - we had it as back-up about 3 months after our counseling). Any questions let me know. My dh has sign up for bubhub as well and just discovered this thread - its a great place to chat with others with these probs. now I just have to catch-up on all that's happened! Good luck with your meeting.
Sent from my iPad so pardon the errors!
17-01-2012 09:21 #114
Hi rae81 - thanks for sharing your story. Wow, 11 cycles. My goodness, you're tough! Do you have some fertility issues too, or any theories as to why it's not happening? Did your DH do have to do the microdissection to find sperm or did they get some with the needle or the biopsy?
17-01-2012 09:55 #115
Wow this thread brings back memories.
As you can see from the beginning of this thread we are doing IVF due to my DH having Obstructive Azoospermia, all his tests came back normal, the only thing that showed up for him was his Karyoptying showing he is a carrier of the CF gene and we were told it was 50/50 if they could find any sperm. DH has had a microdissection, a biopsy and the needle aspiration. All three times they found sperm and the prioceedure is done on the day of my egg collection. Unfortunately there is only very minimal sperm retrieved literally only around 50-100 individual sperm each time. (It may not sound like a lot but you only need one sperm per egg so i am happy with this result). The additional biopsy/aspiration procedure adds around $4000 to our cycles and we only get back around $500 from Medicare and Private health even though we have been with them for well over the 12 month waiting period. We aren’t able to test the sperm using the traditional tests as there are so few and so immature but we have been told there is no fragmentation as they are collecting it so early and the Morphology is good. Due to the low numbers we need to do a biopsy/aspiration each time i have a fresh cycle. So far we have done 7 cycles and I’m currently doing a FET cycle, you can see my signature that we haven’t been successful yet. I have no known issues and have been tested for everything. My FS (Dr Lok) has advised that due to the area they are obtaining the sperm they are a lot more immature and therefore it can take a bit longer to conceive using testicular sperm. DH is very against Donor sperm so we will be continuing a fresh biopsy each time we do a stim cycle, due to this we need to wait at least 3 months in between each stim cycle as the testes need time to heal and rejuvenate more sperm again.
I wish you all the best for your journey, when will you start the meds for your cycle?
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MGC Bertie (01-11-2012)
17-01-2012 10:36 #116
17-01-2012 12:16 #117
Hi EternalOptimist - you're familiar to me from other threads, I'm sure!
So, it seems from both your responses that your respective men have had these procedures more than once. That is very interesting. We kind of had the impression that this is the last chance. So Dr Lok did the needle aspiration - nothing, then the biopsy at the same time - nothing. After the biopsy, tissue was sent off for analysis and the result came back as Sertoli-cell only syndrome. Dr Lok didn't seem to think there was any hope & was talking about donors. But Dr G thinks if he opens the testes right up and looks through every part of them, he has a 50/50 chance of maybe finding some, as he has had good success rates in his recent procedures. But I got the impression this is one-shot only deal - there will either be some there (and they'll get it & freeze whatever they don't use) or there won't be any. He also did not give us any instructions on lifestyle before the procedure ... although DH is taking Menevit and trying to eat healthy, just in case it helps.
I have an appointment tomorrow AM with the FS to find out more about the cycle and my meds, etc. I don't really know anything about that at this point. All I know is that, in all the tests I had previously had done before I went ahead with my fibroid surgery, everything was perfectly fine except for thyroid - TSH level was prob a bit high. They took blood on Fri to re-test that, so will find out more tomorrow!
17-01-2012 13:25 #118
peoniesarepretty - If Dr G can't find any active tubules then it's likely there are no germ cells anywhere and that's the end of that. Lifestyle won't help produce sperm when there are no germ cells present.
If sperm are found, then you can try to find them again the same way on another cycle if you need to. Lifestyle might help in this situation.
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17-01-2012 13:43 #119
Thanks Felicita! Makes perfect sense, and is what I thought. Although I didn't think about potentially doing it again in the future if some are found. Don't think I could put DH through that again. I saw how bruised and uncomfortable he was just after the biopsy!
20-01-2012 16:26 #120
I have just been informed today that my DP has 32% DNA Fragmentation. He also has low count, low motility and morphology, so basically in every cattegory its not good.
Just wondering if anyone has had success high DNA fragmentation?
FS wants us to go ahead with IVF using DP's sperm to give it a try. I also want to do this, but i was also told my AMH was not good for my age, it was 11 and I am only 28....so he said that would just be only "ok" for a 35 year old.
Any advice would be appreciated.
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