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  1. #1
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    Default Possible Partial Molar Pregnancy with IVF?

    Hi everyone,

    Well ill just state the facts:
    Ivf with icsi done,heartbeat seen at 7 weeks then gone at 9 weeks. D and C done a week later and sent for testing. Some results have come back indicating possibly a molar pregnancy. Have to have blood tests starting as of next week to check hcg levels . How is this possible if we had icsi done?? Shouldnt this have been picked up by em embryoligist before the embryo was even replaced? Im so stressed as to what this all could mean, possible chemo and having to wait up to a year to try ivf again! Im so angry and upset... Does anyone have any experience with any of this? Please cause its going to do my head in!

  2. #2
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    Hi there, I don't know alot about Molar pregnancies but I found this. Hope it is of some help for you. So sorry your cycle didn't turn out well.

    http://www.babycenter.com.au/pregnan...cations/molar/

  3. #3
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    Hi there,

    I have NO idea about IVF but as you can see by my signature I had a molar pregnancy this June. I had an u/s done at 6 weeks and there was signs of the pregnancy being multiples but no heartbeat, then when I was 9 weeks they couldn't find a heartbeat on the u/s just a mass of grape-like white balls. Basically a molar is a cancerous tumour (a rare type of pregnancy cancer, not often too serious) that takes over the fetus and often you have over-exaggerated symptoms so shocking morning sickness, even showing very early because the tumour is large etc...I had a D&C done and had bi-weekly bloodtests for 6 months and now my HCG is down to zero and we can start TTC again . I had a chemotherapy drug called methotrexate injected into me because it stops cells from dividing, thus, stopping the tumour from returning. It is VERY rare that full chemo is needed.

    Its hard to find info on this because even medical professionals are baffled by molars. If you want any more info please dont hesitate to private message me.

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  5. #4
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    Yep, molar pregnancies are not due to a known fault in the embryo. It's basically an overgrowth in the placenta and no-one really knows what causes it, although they may have isolated a gene that makes someone more likely to have one.

    It's a really stressful time and incredibly traumatic as you go through the follow-up blood tests. At least I thought it was. Each blood test was a reminder of what we had lost, and the time we had to wait, not to mention the chance of chemo.

    Do know that invasive moles are rare (the ones that need chemo), and there are lots of success stories after molar's.

    I'm one of them. I'm so proud to finally have my little boy in my arms.

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    Default My explination....

    No one really knows what causes a partial molar pregnancy, and it happens in about 1:1500 pregnancies and has not ever been recorded to produce a live birth.

    My very simplified (and probably slighty off) explination is that the placenta cells can overgrow due to a mistake in cell division.

    This overgrowth of the placenta can eventually kill the baby growing or even prevent it from forming very far. It will result in miscariage.

    Be it natural or other the Dr's recommend anyone with molar tissue have a D&C to remove all the remaining placenta cells as a precautionary measure.

    This is very important because these placenta cells can regrow, even without a fetus being present.

    In the case that the cells do regrow they are rogue, and will multiply when they shouldn't, so are identified as precancerous cells. Left to divide they will quickly move to the lungs and other parts of the body as cancer.

    Luckily because of the type of cells they are thier cell division releases the HCG hormone also found in pregnancy. For this reason a woman who has suffered a partial mole is advised not to fall pregnant immediately, as the Dr's can watch the beta HCG in her blood for possible tumour indicators.

    There are conflicting ideas on how long someone should wait to ensure the molar tissue doesn't regrow, but general consesus for a partial mole is 6 months from a negative HCG result (under 5). A complete mole is a much nastier story and my hats off to any ladies who has experienced this.

    Although I have been in contact with around 15 ladies in France and Australia who have had partial moles, I only know one with a complete. Coco we love you and support you, hopefully this will be your last round of chemo, and the specialists will find that gene they've been talking about.

    Not all partial Moles develop the same way. Mine had no visable 'grape like tissue' and I had no bleeding even at 13 weeks when the baby was removed. My baby did have a heartbeat, but development was arrested by the condition.

    I'm also happy to chat anytime

  7. #6
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    So sorry about your loss -being diagnosed with a partial molar is heartbreaking. Yes, a partial molar is possible with ICSI - I think the explanation was that even though only one sperm fertilises the egg, the sperm can still divide and give two sets of chromosomes.

    I lost a baby to a partial molar pregnancy in May this year (heartbeat at 6 weeks and then baby died the very next day it seemed). I thought about ICSI as an alternative to prevent a partial molar occuring again but discovered that partial molars can happen with ICSI anyway. I have been on a UK forum and there was a woman there who had a partial molar with ICSI.

    The follow up after a partial molar is poop. It's very stressful waiting for your HCG to come down. It took 8 weeks from d&c all up - and the last four weeks of that my HCG was under 10 - so frustrating! But that is the normal pattern as the HCG slows right down towards zero.

    And with the waiting period after a partial molar, well, that was awful too. I'd already had a normal m/c in April 07 but was lucky enough to conceive my DD about six weeks after that. And there I was after the partial molar being told I couldn't conceive until six months from zero. I struggled a lot with that. And it seemed that everybody around me was announcing their pregnancies, I wanted to scream. In the end we waited one month from zero and decided to try again. I did have to present all my research to my DH first. I felt like I should have had a laser pointer, projector and worn my glasses.

    Anyway, we got pregnant that first go to my surprise and we are expecting another DD in May.

    All is well, I will just have to get my placenta tested after the birth for any abnormal cells. But that is routine after a partial molar pregnancy.

    I know it's a horrible time, but you only have a very small risk of needing chemo - chemo is much more common with a complete molar pregnancy than a partial molar.

    You will get through this, it does get easier. When you are zero you will feel a great weight off your shoulders. Still it was one of the most difficult things I've been though and I won't forget the experience. I can't wait to get my post molar baby in my arms!

    Izy - I spoke to you after my diagnosis of a PMP - congratulations on the birth of your son!!!!

  8. #7
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    Hi all,

    I had a partial molar , only discovered after D&C.
    2 emergency admissions after, due to side effects of extreme high hormone levels.
    -thrombosis
    -twisted ovary due to cysts, emergency surgery followed, boy oh boy the pain!

    So please if you have molar pregnancy make sure you have your pelvis scanned after D&C!

    This was all in nov 17. Now pregnant again!, 20 weeks and going along ok!

    Keep the faith and happy to talk if you are experiencing the same! PM me.

    DVD.


 

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