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Lack of Luteal Support

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  • Lack of Luteal Support

    Hi everyone.. after 10 years of IVF we have just had one of the worst things happen. our last embryo (from the 5 year you're version of my now 43 year old self) PGD tested - all looking good , immune drugs on par.. it was sowing HCG from 3 days after the 5 day transfer.. Turns out my clinic did not relay the correct dose of Progesterone to me that my doctor had prescribed. I started to bleed like a period on day 28 of cycle, and at the same time the HCG continued to rise as if a viable outcome was likely right through until day 4 of the period. when it disappeared within 36 hours. It is very clear to me the lack of Progesterone caused my lining to shed and consequently the implanted PGD embryo got wiped into oblivion. I am beyond devastated . at 43 there is no more next times.. Has anyone else suffered in this way? I suppose you could call this "Lack of Luteal phase support" my doctor dodged the question and did not deny this is the likely cause, and instead just said "you won't find anyway to get that answer" .. meanwhile.. my life is defined, my heat is broken, and they have taken $15k from me for good measure.. The clinic and nursing team did not clearly communicate with me my dosage for progesterone as i required maximum dose due to my age and irregular cycles. I would love to hear from anyone that has experienced HCG rising at the same time as having a period. I feel battered and bruised.

  • #2
    No experience with what you have been through. I just wanted to send love and support your way. Please be kind to yourself. You are in my thoughts

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    • #3
      I'm so sorry to hear your story of struggles. Still I'm of no help here as my case differs. I've never experienced problems with luteal phase..But I know this failures' pain.
      I'm 40 yrs old, dh is 50. We'd previously tried out 3 iuis - all failed and OE IVFs - the same outcome.Finally turned to DE IVF overseas. (Made this decision primarily for more affordable prices). Besides we could choose the donor ourselves. Of course our doc was to have his last word, but their donor database turned out to be really huge..
      I also wanted to ask you for updates.
      Stay strong, all my positive thoughts going your way.

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      • #4
        Hi There,
        I didnt experience HCG rising it was falling if anything, however my clinic failed to tell me to go test Progesterone levels next day of the transfer ( their lazy response was - miscommunication) With that failed FET we came to a discovery pessaries do absolutely nothing for me and I was switched to PIO, but it was too late. Progesterone is my weak spot too, as I know from before when I had a natural pregnancy ( that resulted in miscarriage) progesterone was around 7-20 at 4-6 weeks gestation. If you check the Reproductive Biomedicine online, there is a lot of evidence on that first few weeks of luteal support. Maybe worth checking too if you are into self search.
        Last edited by Sonia Russo; 01-10-2021, 17:14.

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        • #5
          Originally posted by Lea7 View Post
          Hi everyone.. after 10 years of IVF we have just had one of the worst things happen. our last embryo (from the 5 year you're version of my now 43 year old self) PGD tested - all looking good , immune drugs on par.. it was sowing HCG from 3 days after the 5 day transfer.. Turns out my clinic did not relay the correct dose of Progesterone to me that my doctor had prescribed. I started to bleed like a period on day 28 of cycle, and at the same time the HCG continued to rise as if a viable outcome was likely right through until day 4 of the period. when it disappeared within 36 hours. It is very clear to me the lack of Progesterone caused my lining to shed and consequently the implanted PGD embryo got wiped into oblivion. I am beyond devastated . at 43 there is no more next times.. Has anyone else suffered in this way? I suppose you could call this "Lack of Luteal phase support" my doctor dodged the question and did not deny this is the likely cause, and instead just said "you won't find anyway to get that answer" .. meanwhile.. my life is defined, my heat is broken, and they have taken $15k from me for good measure.. The clinic and nursing team did not clearly communicate with me my dosage for progesterone as i required maximum dose due to my age and irregular cycles. I would love to hear from anyone that has experienced HCG rising at the same time as having a period. I feel battered and bruised.
          So sorry to hear your story. I have a similar one unfortunately. Our very first ivf resulted in a positive HCG result and my doctor told me I only needed progesterone until 13dpo.. you can guess what happened next, my HCG rose but I started bleeding and then it was too late. The doctor tried to say it had nothing to do with the progesterone as my HCG was low but I disagree and now know better:

          17dpo hcg 126 prog 11
          20dpo hcg 500 prog 9.3 - start bleeding

          My doctor now says they don't take anyone off progesterone until 12 weeks,

          It sucks. It has been a long road for us since then now 10 years on and no baby.

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