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    Question Unexplained Chemical Pregnancies

    Hi everyone,

    After some googling I've just come across this forum. So am super new here new here and looking for information and experiences really.

    I have been TTC #2 for 5 years now and am unexplained (#1 was conceived 2nd month trying). Over the 5 years I have gotten pregnant on my own, with the help of clomid and other things, and also with IVF. But every.single.time I have have a chemical pregnancy, never getting past 4.5 - 5weeks before AF arrives. I've had what feels like every test imaginable, thyroid, progesterone, blood clotting, immunological testing, chromosome testing - you name it! Have had hysteroscopy and laparoscopy with all coming up peachy!

    I guess what I'm looking for is any advice on anything that could be missing? Anyone have similar experiences with CP's?

    We are about to go into our next FET and guess I am just hoping someone somewhere has a similar situation with a successful outcome

    Thanks in advance for reading and or commenting.

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    Summer  (25-08-2016)

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    Sorry to hear you have been going through this. I'm subbing to see what others say. Over the past 15 months I've had nothing but chemicals and early miscarriages too. Hope you find some answers and have a successful FET next time around!

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    Summer  (25-08-2016)

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    Quote Originally Posted by Ashjay View Post
    Hi everyone,

    After some googling I've just come across this forum. So am super new here new here and looking for information and experiences really.

    I have been TTC #2 for 5 years now and am unexplained (#1 was conceived 2nd month trying). Over the 5 years I have gotten pregnant on my own, with the help of clomid and other things, and also with IVF. But every.single.time I have have a chemical pregnancy, never getting past 4.5 - 5weeks before AF arrives. I've had what feels like every test imaginable, thyroid, progesterone, blood clotting, immunological testing, chromosome testing - you name it! Have had hysteroscopy and laparoscopy with all coming up peachy!

    I guess what I'm looking for is any advice on anything that could be missing? Anyone have similar experiences with CP's?

    We are about to go into our next FET and guess I am just hoping someone somewhere has a similar situation with a successful outcome

    Thanks in advance for reading and or commenting.
    Sorry to hear you are going through such terrible miscarriages. Can I ask how old you are? It may be egg quality, my SIL had the same issue and then tried chinese herbs and poof she was preg again and no miscarriages. Have you also had your NK cells checked?

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    Summer  (25-08-2016)

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    Thanks for your responses ladies. Honestly, I have been for so many blood tests over the years I struggle to remember what's been done. Although I am thinking maybe my NK hasn't been tested. I know it was something I had researched in the past and was recently tested for a whole bunch of stuff but don't recall NK being one of them. Would it be called anything else when being tested? Can a GP do the test or just a specialist? My specialist is away at the moment and my GP is great, I know she would send me for the test if she could???

    Nattie84 I am 35 DH is 37. I had my AMH re tested two months ago and it's great apparently. I have produced some great looking embryos - 6 frozen ones from my last IVF - 3 of which we have already used

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    Summer  (25-08-2016)

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    Quote Originally Posted by Ashjay View Post
    Thanks for your responses ladies. Honestly, I have been for so many blood tests over the years I struggle to remember what's been done. Although I am thinking maybe my NK hasn't been tested. I know it was something I had researched in the past and was recently tested for a whole bunch of stuff but don't recall NK being one of them. Would it be called anything else when being tested? Can a GP do the test or just a specialist? My specialist is away at the moment and my GP is great, I know she would send me for the test if she could???

    Nattie84 I am 35 DH is 37. I had my AMH re tested two months ago and it's great apparently. I have produced some great looking embryos - 6 frozen ones from my last IVF - 3 of which we have already used
    AMH is really more of an indicator of quantity not quality. The NK cells test needs to be done by a specialist as not all doctors believe in it and I had it done at the hospital clinic not all normal blood collection centres do it. It is a blood test firstly and then a uterine biopsy to confirm if levels are high. It is called the NK Cells test.

    Have you also looked at having your embryos tested?

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    Summer  (25-08-2016)

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    Thanks Nattie. I don't think I have had NK cells tested then. I've just checked the last email I had from the specialist with regards to the most recent tests I had done, and he just mentions that "you did not have any significant abnormal antibody levels including a negative result for lupus anticoagulant, negative results for the anticardiolipid antibodies and thyroid autoantibody levels within the normal range".

    Specialist has mentioned having them tested in the past maybe once, but is fairly certain it won't result in anything so hasn't really wanted to go down that path at this stage. Perhaps it's what I next need to push for?

    So much to consider when trying to find a reason! Aaaaggghhh
    I'm quickly becoming well and truly over it.

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    Summer  (25-08-2016)

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    Quote Originally Posted by Ashjay View Post
    Thanks Nattie. I don't think I have had NK cells tested then. I've just checked the last email I had from the specialist with regards to the most recent tests I had done, and he just mentions that "you did not have any significant abnormal antibody levels including a negative result for lupus anticoagulant, negative results for the anticardiolipid antibodies and thyroid autoantibody levels within the normal range".

    Specialist has mentioned having them tested in the past maybe once, but is fairly certain it won't result in anything so hasn't really wanted to go down that path at this stage. Perhaps it's what I next need to push for?

    So much to consider when trying to find a reason! Aaaaggghhh
    I'm quickly becoming well and truly over it.
    I know it is soo hard! If you have NK cells it can cause recurrent miscarriages so best to get them checked to have piece of mind. Good luck

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    Quote Originally Posted by BabyG4 View Post
    Sorry to hear you have been going through this. I'm subbing to see what others say. Over the past 15 months I've had nothing but chemicals and early miscarriages too. Hope you find some answers and have a successful FET next time around!
    Thanks babyG, I'm so sorry to hear of your losses! Can I ask how many you have had and if doctors have found any reason for it all?

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    I'm up to 5 or 6, kind of lost count in the last 15 months. I keep getting my hopes up just to be let down again. No reason for the losses though. Plan on doing early blood work next time around.

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    Default Unexplained Chemical Pregnancies

    I've just had my sixth chem, with four this year. I don't have NK cells in blood, but could in uterus. Prior to this I had four pregnancies that ended between 6-10 weeks. I am looking into many things now, but my chems end within 24 hours of using a progesterone pessary.

    This time I even had my bloods checked & had hCG of 28 & progesterone of 76 naturally at 3w5d which is perfectly on track. Then because of my recurrent miscarriages the schedule I started on was progesterone support, clexane, prednisone & baby aspirin. I started with the progesterone & 24 hours later the line faded out. I don't know if it is a coincidence but that exact scenario has happened with all six chems - everyone tells me that progesterone can't cause a miscarriage, but the research I'm doing seems to show that some women can have a sensitivity or allergy to progesterone & it can increase immune activity which could result in a NKC attack on the embryo.

    I might be right off track but I'm investigating this further now & will be consulting Dr M about it. The awful thing was that my natural progesterone was fine so I didn't need the support - I wonder what would have happened if I'd just done the other things without the progesterone? It's rare so I'm not saying it would be a common cause of chems but I have a lot of allergies & it's a path I'm exploring further.


 

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