I have just completed 5 IUI and 17 IVF cycles over the last 3.5 yrs, and thought I'd share my experiences in hope that someone else will find it beneficial.
On the 17th IVF attempt, and when I was just about to give up, I fell pregnant and have just delivered a healthy baby boy.
I was considered a low responder as I was averaging 2-4 mature follicles and 1-3 eggs collected at each cycle. All except 2 cycles ended with a transfer on day 3 or 5.
These were my stats in the last 12 months:
Antral follicle count: 10
FSH at day 3: >10
In the last 2 cycles, my mature follicle count jumped to 5 and 9 and eggs collected was 4, which was a significant improvement. Here is what changed in my last 2 cycles:
*600mg of Coenzyme Q10 daily
*Changed from Menopur to Gonal F. Menopur contains LH which can convert to testosterone which can ruin egg quality.
*Stopped taking DHEA during FSH stimulation.
*Started estrogen priming for 7 days prior to the beginning of the cycle.
I believe that the estrogen priming lowered the naturally occurring FSH levels during the luteal stage which increased the number of mature follicles produced when FSH stimulation injections started, and the elimination of extra testosterone improved the egg quality.
Over the 17 cycles I have had my share of quack fertility Drs, and also a Dr who told me to give up, so I changed Drs. Multitudes of failed attempts is emotionally draining, but as long as you are producing at least 1 transferable embryo there is always hope. Hang in there and don't let anyone else tell you when it's time to give up. It can happen.
If you are a low / poor responder ask your doctor about estrogen priming.
Good luck to everyone.