keepontrying13. We wasted thousands we could not afford on FS#1 and now know there is not a hope in hell it would have worked. Plus of course time and stress. It's very frustrating. I'm glad we found Wazza before it was too late and Charlotte is awesome too. Our time with FS#1 likely means we'll only have one, whereas if we'd stared with Wazza back then we'd probably be working on no#2 now. FSs change our lives.
We are lucky to get one or two day 5 embie per cycle and they are usually CCs. I have PCOS, so we get a decent number of eggs, but they are old and PCOS dodgy. If you do 5-day PGD it is $750 per embie. They can biopsy a 6-day and if you transfer that as a FET it has as much chance as any other normal embie.
Do you use PICSI? We found that increased our fert rate and also the number of day 5/6 embryos - taking it from none to one or two. I'd also suggest letting the supplements build up for 4-6 months and making sure both you are DH follow instructions religiously. We did embryo banking for the last couple of cycles, PGDing what we could. This allows your body to recover from stimming and I found not doing a fresh transfer made a huge difference to my health and wellbeing. The FET was a breeze by comparison and I knew that there was nothing untoward going on post EPU that might jeopardise a good embie implanting. We transferred 3 PGD normals over 2 ETs and one has taken. I think 1:3 is the average. I also found I got better embies on the second of two back-to-back stims, so that was another reason not to do a fresh transfer as I think I'd have found that too much.
From what you've said I'd be tempted to do PGD and then when you get a normal you can concentrate on preparing your uterus, knowing it's got a much better shot of working. If you want more than one then I'd be inclined to embryo bank as well. I'd have thought with BB or BCs you'd have a good chance. It can take a few cycles though to get a normal, but what is the point in transferring an abnormal and putting yourself through the TWW? Ours that has taken was either a normal cavitating morula or a 5BB, although we may never know (if they were different gender, once we know bub's gender we'll be able to figure it out - if QFG will give us that info).
I hope that helps in some way, or let me know if you have any more specific questions.
Thanks @Gagingi this is really helpful. I'm glad I'm not the only one that has wasted thousands of $$$ on crap FS. Really breaks your heart dosent it. Glad we found Charlotte but totally agree would have been great to find her a couple of years ago but no doubt in my mind we are in the right hands now.
I have PCOS as well and like you produce alot of eggs but they all tend to drop off around the day 4-5 area. We get good fertilisation results and only use ICSI. Thats good to know you found doing back to back cycles gave you better embies...something to think about I guess. I have really found this first cycle with Charlotte the hardest for me out of the many I have done. I think its all the drugs she throws at me!
We would be happy with one bubba and cant see myself having any more than that. Hoping the next STIM we do we can get 2-3 to test. Looks like they give you a good average as well! I'm hoping the two we have in the freezer will be it but I have learnt from experience not to pin my hopes and always have a plan going forward!
Again thanks for the info and good luck with your pregnancy!
@softshellcrab sorry to hear you've joined the club. It's very boring and frustrating. How far along are you? It's scary, but the great thing about Wazza is that he does everything he can and knows this pregnancy caper inside and out.
I'm glad work responded better than expected. Did you tell them why or are you getting med cert from your GP? The good thing about 4 weeks is that it is obviously serious.
@Keepintrying13 as a lot of women on this thread will attest the drugs work for embies, but knock a lot of us about. I had a couple of bouts of excessive drug toxicity, keeping me off work and turning me into a hermit when stimming. It's hard, but worth it.
Maybe ask about PICSI if you need to do another stim cycle. It's $200 I think. It's non invasive and they get sperm to swim through a substance similar to the coating around the egg. Those that can swim/attach are genetically stronger, as like eggs and embryos, a good looking sperm might be a dud. I think for ICSI it is a brilliant idea as ICSI takes out natural selection, whereas PICSI brings it back in. Whilst many factors influence embryo development and the egg is important the whole way through, sperm plays a bigger role days 3-5 - in combo with egg (my DH thought it was all his fault if embies fell over days 3-5, but Wazza said combo).
Thanks for your well wishes.
@Keepontryin13 - Good to see you back here hun, a break is sometimes needed hope your in a good space again. Great to hear Charlotte has a plan for you, I really feel we are in a similar position and its a numbers game for us too! We have opted for the pgd testing too as feel it just gives us the little bit more information, it feels good knowing we will hopefully be putting back a normally tested embie this time if it survives its got to up the chances you would think. In the end we only had the one embie that had survived the thaw as ours were frozen embies and we still tested it so I would test whatever number you get hun.
@softshellcrab - So sorry to hear that hun, make sure you do rest and take it easy!
@MamaKes - Sounds like you're resting up well hun keep it up. I was in for intralipids yesterday and the nurse was saying she had a mothers group in the day before, that must have been you ladies haha! Being admitted to st andrews for a few days sounds like a very good plan.
AFM - Full on day yesterday left the house at 4am and didn't get home until 4pm, came home with a huge headache and took myself to bed early 😴 My appointment went well I got the go ahead to start injections and we have added in the growth hormone. Wazza has now got his hands tied and isn't able to do double transfers even though my last one was double so we will just be putting back our one pgd tested embie and any fresh we get will be tested.
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