Just a side note
I didn't have egg quality issues
But dr m thought cause of fert results could have been better
And he medicated me for my eggs between phone consult 1 and 2
And i fell naturally in that time
So on phone consult 2 (found out i was pregnant the Thursday and was alreddy booked with him friday)
He medicated to keep baby alive (which at a guess.we thought we werr 5-6 weeks along)
So it had survived well on its own for a week or more
Started ivf at 27 i think (started trying for baby around 26
I literally found out i was pregnant in the ivf specialist office
I thought i was just late cause of ivf haha
So i was on nothing, except vitamins and meds gave me for eggs
I only went on immune protocol at 6 weeks pregnant..
Keep in mind i had, had chemical pregnancies but never been that pregnant before
Im only sharing as dr.m looks at the whole picture
Of eggs and auto immune ect ect
As no one will have the same story or . issues
Having high ANA and anti thyroglobulin antibodie don't mean you have high NK cell. NK cell is a different thing. Everyone has NK cell. It just depends how strong they are. If it will see the embryo as a foreign object in the body and kill it off.
Ladies I need your help I am unsure where to go next. A bit of history...
32 now, started trying for a baby in 2010, started IVF in 2012.
- mild endo removed twice and third surgery found none (this year)
- MTHFR - hetero a1298c - doctors say this shouldn't cause an issue
- DH has low sperm morph but above average numbers and mobility so doctor's say all good
- AMH 40 so all good here
- regular 28 day cycles with chinese herbs (although progesterone seems to drop real quick)
- NK cells normal
- Low T cells
- no sperm fragmentation issues
- no DQ Alpha matches
- two early (<5 weeks) chemical pregnancies from IVF (first one I believe is due to progesterone, 2nd have no idea), no other pregnancies
- IVF never yields good eggs:
2012 MARCH IVF ICSI 13 eggs, 7 mature, 4 fertilised, 2 grade A - TFR #1 Chemical, TFR #2 BFN + MILD OHSS
2013 MAY IVF ICSI + PGS (DAY 3) 16 eggs, 6 mature, 6 fertilised, 6 grade A, 1 normal PGS BFN+ MILD OHSS
2016 AUGUST IVF ICSI (new clinic - long protocol) 6 eggs, 2 mature, 1 fertilised Chemical
I saw Dr M previously and we tried entrepalids (sp?) clomid with clexane and dex as at that stage NK cells in blood were high (later on had biopsy done by Dr Reid and found to be ok). But basically doctor's now are baffled and we are in the unexplained category. I just don't know what to do, I am close to giving up but I want to be a mum. I just feel like the chances of success of IVF are like winning the lottery and I would be better off spending my money and time on other things to be happy.. I have also had three different FS now....
Can anyone give their opinions as doctors seem to fail me...
Last edited by nattie84; 05-09-2016 at 12:54.
We have used Gonal F on all stim and FET cycles.
PGD didn't help this time as we only got one embryo so we decided to put it in fresh to save on another cycle.
I think I will get Dr M to review the NK cells testing and everything else.
Ladies I found this link which makes sense: It says
Blood tests can only measure the circulating NK cells in the body and not the uterine killer cell activity, which can be the cause of recurrent miscarriage. So, if you have had a blood test, it is not measuring what is needed. Everyone will have circulating NK cells in their blood ******.
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