I would definitely leave everything in his hands - but I also wouldn't lose my mind if he slacks off a bit with it.
So with the room for example - let him live in his filth and he can deal with the consequences of that. That said, I would be saying, "we have a rental inspection (or important guest or whatever) on XYZ day, and your room MUST be tidied. If it's not, then there will be consequences." This is fair IMO, and it's very much how real adult life works, so it's an actual lesson in responsibility.
Don't fold his clothes. Don't make his lunch. Let him be responsible for that. Hell, I'd eventually add a lot more chores in too - partly because he needs to pull his weight, but partly because that's how he will learn to be a functional adult. I didn't even know washing machines had a filter and was wondering why my clothes were always awful. My mother never showed me (she did all the washing) and never mentioned that there was even such a thing (ours was filter-less). I felt really inadequate as an adult just from not even knowing this stuff.
I even know young adults who don't know how to sweep a floor. I watch them and it's about the same as watching a toddler drag one around. Chores can help you learn for adulthood, and I think it's really very important for him to learn that responsibility now before it's essential.
I'd still be fair though - I wouldn't want someone saying, "You're less important, thus you must end your game smack bang in the middle of it because I want to do something and you're preventing that." Instead a more reasonable, "after that round/in 10 minutes/etc," or even "how long until you reach a save point?" etc and just being reasonable and fair. I think you get respect back when you give it as well, and of course you could say the same of him, but he's a kid... he has to learn from you, not be expected to just understand how it works.