@Sue77 that is a fabulous egg haul! Congrats on that great start and let's hope there is a good quality embie or two come out of that lot! Great that you had a nice night with DH as well, that always helps.
@Bongley I bet you can't wait until the follow up tomorrow, what a stressful cycle this one has turned out to be. Hoping it all gets underway for you ASAP and that this is the golden embie for you.
@Blossom74 that new FS sounds lovely and I second the other girls, if you feel more comfortable with him and the costs are not a lot different then go for it. You need to have as many people on your team that you feel are really wanting this to work for you as you can, and if he's it, then don't feel bad about changing FS. And your cakes look AMAZING! My Mum makes Christmas cakes that look like that. She's never taught me how to make them though, and as a mother she leaves a hell of a lot to be desired, so I don't think I'll be getting that family recipe anytime soon
@Tahli I'll be looking out for your updates! Hoping it's all coming together for you with SD2's super-dooper embies!
Hi to everyone else, hope you have a great weekend I'm still unpacking from moving - oh the joy
Hi @calypso75 - the way it was explained to me by the nurse was that intralipids (or TPN for patients with poor nutrition!) can be extremely irritating to veins. Particularly when adminstered through a peripheral line (which is the technical distinction for a short cannula in your arm). Normally if we give this to malnourished people in hospital, we put in a PICC line so it is fed into a much bigger vein (subclavian vein or supra vena cava).
So to make sure there's not too much irritation they infuse it with normal saline. They start off slowly at 100ml/hr and if everything is fine after 15 mins with the cannula, then they will increase the rate to 150ml/hr. Alongside this, through a 3-way tap, is the normal saline running at a constant 100ml/hr.
So all up I had 500ml of 20% intralipid and probably only 450ml of normal saline. It took about 3.5hrs of infusion time.
As to the total dose, well, I suspect that Wazza was hammering me because my numbers are well over the 75 centile (prob closer to the 98 centile). Don't know what I've been doing, but I am clearly a natural killer!
Whether they give smaller doses for lesser NK levels, I don't know. I'll ask Wazza next time I see him.
My advice is to go with whatever protocol the FS you feel most comfortable with says. It's not main****** medicine and immunology is a very crude field, let alone reproductive immunology, so the evidence isn't robust. Though just because there's a lack of evidence, doesn't mean it doesn't work.
It just frustrates me how little formal research is being done on all of this. If I ran QFG....!
Last edited by princessrory; 05-12-2015 at 14:02. Reason: spelling boo-boo
Double post. So sorry!
Last edited by princessrory; 05-12-2015 at 14:03. Reason: Double post. Newbie doofus.
princessrory I was at St A's for an infusion yesterday and I'm with Wazza too - we might have crossed paths . It sounds like we had exactly the same intralipid protocol/rates. I don't know my NK levels, as Wazza started me on intralipids as I have Adenomyosis and Endo which are associated with immune issues too. Not sure what my NK cell levels are...
I agree there needing to be more research, but having done health research I can imagine the ethics nightmare that would be, and I for one wouldn't sign up for a control group where I may or may not get the treatment, so I don't think it will happen. Thank god for Wazza!
Last edited by Gagingi; 05-12-2015 at 19:44.
@Sue77 - great egg haul - good start. I know all about the drops off - hopefully you can get a few good ones.
@Gagingi - that's all sounds pretty good to me! I did the HA ICSI both cycles which I think is the same thing as PICSI, even though DH has no apparent sperm issues form two tests so far but I figure do everything I can to get the best chance. How did you get your PGD results back so quick? Mine took 3 weeks again this cycle - but was a day 5 biopsy and was a full chromosome screening.
fingers crossed you get another normal to freeze. I'm doing 300 menopur with melatonin this cycle .
Wow @Sue77 what a haul, congratulations !
Good luck and safe travels @Tahli, this trip will be your last I'm betting. Will be stalking for updates.
Happy birthday @infinity888, spoil yourself and NO housework. @Bongley, you're sounding a lot saner than I would be in your shoes. Nice work keeping it together.
Good luck @Gagingi, sorry to hear you had all those issues after EPU but sounds like you got through it ok.. And congrats on being PUPO !!
Welcome @princessrory ! 1100 calories? They never told me that, mind you on top of the prednisone bloat what's a bit more... Still waiting for it all to drop off me but I've only been off the prednisone and hormones for a week now.
And what a crap week it's been. I was likened to a snapping crocodile a few nights ago. Poor DP. He's so nice about the way he tries to tell me to pull my head in, even when I can see myself being horrible I just can't stop. I'm fatigued, unmotivated, feeling crappy, headaches coming and going, over worked and just generally bleh. But, I'm 13 weeks now so should be feeling great. I'm not.
Last edited by JulieMalooley; 05-12-2015 at 15:59.
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