+ Reply to Thread
Results 1 to 7 of 7
  1. #1
    Join Date
    Oct 2015
    Posts
    26
    Thanks
    3
    Thanked
    4
    Reviews
    0

    Default PCOS - Clomid 3x unsuccessful - now what?

    Hi ladies - I'm totally new to posting, so excuse any mistakes please! My husband (28) and I (31) have been TTC for almost a year now and I found out I had PCOS about halfway through the process (he was tested and has no issues). Had 34-day cycles before starting any medication with 6-7 days of "high" ovulation test results followed by a "peak." Saw a FS and got on Clomid 50mg with no real results - took another dose of 100mg for 5 days without bringing on a period and had good results (one dominant follicle) but no pregnancy. Did a third round recently and had the same results as the first time - no progress, low estrogen and no dominant follicle. Waiting to hear what the doctor says, but has anyone had similar experience? I know people try for much longer, but I don't know how - I am already at my wit's end and struggling with jealousy Any advice or support is appreciated!

  2. #2
    Join Date
    Aug 2013
    Posts
    4,177
    Thanks
    1,267
    Thanked
    2,580
    Reviews
    0
    Achievements:Topaz Star - 500 postsAmber Star - 2,000 posts
    Awards:
    100 Posts in a week
    I was diagnosed with PCOS about 12-14 months ago. I've been on 100mg clomid for 10 cycles all up now. No pregnancy as yet. With 3 of those cycles we did IUI also with no luck. Our next step is IVF but we won't be doing that until later this year/early next year. In the meantime my FS is happy for me to continue on the clomid unmonitored as my response has been fairly consistent (3-4 dominant follicles). I get what you mean about the feelings you get, but I'm in a place now where whatever will be will be. I can enjoy my friends pregnancies and babies with no hard feelings. One day it will be my turn, maybe it won't. But we'll cross that bridge if and when we come to it.

  3. #3
    Join Date
    Oct 2015
    Posts
    26
    Thanks
    3
    Thanked
    4
    Reviews
    0
    M'LadyEm - do you have any other symptoms of PCOS or do you take Metformin? I don't seem to have any insulin-related issues, but have severely oily skin and terrible cystic acne (being off BC and taking all these meds is doing nothing for me in that department). My FS didn't think I needed Metformin, but I've read that it has helped a lot of people, so I'm considering asking her again.

  4. #4
    Join Date
    Aug 2014
    Posts
    2,267
    Thanks
    2,356
    Thanked
    1,885
    Reviews
    0
    Achievements:Topaz Star - 500 postsAmber Star - 2,000 posts
    Hi there sorry to hear of your struggles, it is tough. So were you ovulating pre-clomid and are you ovulating on clomid or not? Have you had a hysterosalpingogram to rule out Fallopian tube blockages?
    I have PCOS and had 2 clomid cycles with no ovulation then went onto metformin which made me unbearably ill so I stopped after a month and moved onto oVulation induction with FSH injections. First 2 cycles I did ovulate but BFN then had the hysterosalpingogram which showed my tubes were clear so that ruled out that issue. I then had another FSH injection cycle with IUI but still bfn so we went onto ivf.
    We had one stimulation cycle got 11 eggs, 7 fertilized and 5 made it to freeze (I got OHSS so couldn't have a fresh transfer). I then had to wait a couple of months for everything to settle and had another FSH ovulation induction cycle to have a frozen embryo transfer in November last year. Which is now a 15 week old baby girl. All up this took 2 years from start of treatment to bfp.
    Sometimes it does take a while and maybe clomid isn't the right option - there are plenty of things still to try. The emotional side of fertility treatment and unsuccessful treatment is very hard and the physical side is hard too on top of that. It's a difficult road but hopefully in time you find the successful combination for you. Hang in there. Chat to your fertility specialist about the possibility of a more aggressive approach.

  5. #5
    Join Date
    Aug 2013
    Posts
    4,177
    Thanks
    1,267
    Thanked
    2,580
    Reviews
    0
    Achievements:Topaz Star - 500 postsAmber Star - 2,000 posts
    Awards:
    100 Posts in a week
    Not to my knowledge. My main symptoms are the infertility, weight gain/where I carry my weight, plus the "textbook" pearl necklace appearance of the cysts on my ovaries (as described by the specialist who diagnosed the PCOS). I've always ovulated from what I can tell, and my periods have always been regular. I have a high AMH which one fertility nurse said is also extremely common with PCOS.

  6. #6
    Join Date
    Oct 2015
    Posts
    26
    Thanks
    3
    Thanked
    4
    Reviews
    0
    Thanks both - I appreciate the support! gingermillie I thought I was ovulating pre-Clomid as I had a regular (albeit lengthy) cycle and was getting my period, but I must have my biology confused because when I spoke to a nurse the other day she said I may get a period but not be ovulating. I was using the digital ovulation tests which indicated I ovulated, but apparently I have very high "normal" LH levels, so perhaps that threw something off. Just feeling confused and frustrated that everything seems fine on paper, but nothing is working. I've not had a hysterosalpingogram but I'll ask about that when I hear from the FS. While IVF is scary to me, I am frustrated feeling like I'm wasting time and I have good insurance that covers 100%, so depending what the doctor says I may jump to that option. We haven't discussed it yet though and besides the basics I know very little about what is involved.

    M'LadyEm I think my AMH is high as well.

  7. #7
    Join Date
    Oct 2015
    Posts
    26
    Thanks
    3
    Thanked
    4
    Reviews
    0
    Quick update - I had a call with the FS last week and we decided to try another round of Clomid at the max dosage. Will start tomorrow and have the first blood test/ultrasound next week. Fingers crossed! How are you ladies doing?


 

Similar Threads

  1. PCOS and Clomid
    By Anasi in forum Polycystic Ovarian Syndrome (PCOS) Chat
    Replies: 240
    Last Post: 12-08-2016, 22:50
  2. PCOS, and new to Clomid-nervous
    By tassiewife in forum Polycystic Ovarian Syndrome (PCOS) Chat
    Replies: 467
    Last Post: 22-05-2015, 20:12
  3. Ovulating with Clomid - PCOS
    By msarahm in forum Non-IVF fertility assistance
    Replies: 4
    Last Post: 13-11-2014, 21:51

Tags for this Thread

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
free weekly newsletters | sign up now!
who are these people who write great posts? meet our hubbub authors!
Learn how you can contribute to the hubbub!

reviews
learn how you can become a reviewer!

competitions

forum - chatting now
christmas gift guidesee all Red Stocking
Shapland Swim Schools
Shapland's at participating schools offer free baby orientation classes once a month - no cost no catches. Your baby will be introduced to our "natural effects" orientation program develop by Shapland's over 3 generations, its gentle and enjoyable.
sales & new stuffsee all
Wendys Music School Melbourne
Wondering about Music Lessons? FREE 30 minute ASSESSMENT. Find out if your child is ready! Piano from age 3 years & Guitar, Singing, Drums, Violin from age 5. Lessons available for all ages. 35+ years experience. Structured program.
Use referral 'bubhub' when booking
featured supporter
henry and grace
Summer Cool. We are the only brand in the world to use ultrafine Merino wool to produce the finest, softest & most luxurious garments whilst keeping mum and bub cool and dry. Wear them multiple times before machine washing-hard to believe, but true.
gotcha
X

Pregnant for the first-time?

Not sure where to start? We can help!

Our Insider Programs for pregnancy first-timers will lead you step-by-step through the 14 Pregnancy Must Dos!