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  1. #311
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    You should be able to download an emoji keyboard from the app store

  2. #312
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    Quote Originally Posted by leyshoja View Post
    Here's an interesting comment from Dr W at CFC in response to my question about killer cells...

    "we do not believe in killer cells and their effect on pregnancies. Killer cells are a natural phenomen and important part of anybody’s immunresponse"
    This is also what Prof. Bow.man, the head of Genea believes and my previous Genea FS. If it was proven, all FS's would believe in it.

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  4. #313
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    And to be honest, I don't believe supplements work either. The only thing 'proven' that you need is a prenatal vitamin. Coq 10 is on the edge of proven science so I have gone through phases of taking it. I'm a scientist and I review medical research. Do 18 year old crack addicts need 1000 pills to get preg? No. Again, if it can't hurt, why not swallow 1000 pills. Whatever makes us feel like we are 'doing all we can'. I can't do it because the amount of water I have to drink with it keeps me up all night weeing.
    Good luck with transfer Tuxcat and Winsor!
    And goodluck to all those cycling and in the TWW!

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  6. #314
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    yes, my previous FS doesn't treat for these. she said she'd been to seminars and done lots of readings on it and it wasn't clear they caused an issue & she said that some of the treatments were more harmful to your body, so she wouldn't prescribe them. I guess if they do cause a problem & I have too many, it'll stop the embryo. I suspect my major problem is the age of my eggs. but will never know for sure I guess. I hope one day in the future things are more definitive. I was thinking last night that I know so many friends and women who've had ivf, I wonder if our bodies will gradually evolve to suit it more? eg, wouldn't it be good if the bad eggs died off early in the clinic and only the ones left were 100% good so you'd have a better idea of them working or not. hopefully knowledge will improve with research. (it's a nice dream, for women in the future anyway)

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  8. #315
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    The next step is mitochondrial transfer from young eggs to old eggs. They are at the age limit now for own egg ivf. One successful case with a 46 year old in the US, otherwise no success over 44. That is not to say natural preg does not occur later, it does!

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  10. #316
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    yeah I recall hearing about that earlier in the year and wondered if it would help. I used to read books (popular science level) on genetics years ago (+ when I started uni after school I did science and wanted to do genetics & microbiology but ended up changing courses when I got a job). I don't remember it now, but the mitochondria was something to do with the energy of the egg isn't it? and the coq10 helps with that I think? I ran out of those tablets and kept forgetting to get more so I only had them a couple of weeks at the start of the cycle. maybe I should get more.

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  12. #317
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    7 daughters of eve goes into the mitochondrial dna. the author links everyone's (?) back to a common ancestor on the mother's side. I'll have to read it again to remember it & to remember what replacing this would do. I think it's part of the dna that comes from the mother. but I can't recall if there's more from the mother. if so, replacing it reminded me of egg donor (but I could have misunderstood, likely)

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  14. #318
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    Yes the mitochondria are the power houses of the cell. Mitochondrial DNA comes from the maternal line. It's really interesting! Coq10 is supposed to help in the energy supply of the mitochondria of oocytes and other long living cells like heart muscle that have to last us our whole lives. Cows fed coq10 produce better eggs, not proven in humans but 'can't hurt' and is proven to help in heart disease! I should read the 7 daughters of eve! Love all that sort of stuff. Women rule! Ha ha! All tortoise shell cats are female because of a type of mosacism, x inactivation. Anyway it's an ivf thread, I digress.
    Last edited by Skyler; 28-07-2015 at 22:06.

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  16. #319
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    yeah it's a quick read and really interesting. not sure if his ideas were disproven by others but it sounds good to me! ha
    the part about producing better eggs that I don't get, is aren't they already formed (since birth)? I'm not sure which parts can be improved. I think I've missed a whole step in my understanding ie the part where there's still something that can be changed, and if so, which part of the egg is this.

    I think it's nuclear DNA which is the DNA from mum + dad that combines. (the main part). the mum gives energy to the cells via mitochondria (dna), so extra special stuff. (which is another part I'm not there yet on donor eggs for me. I know I've left things way too late, but it's hard to admit tha my dna isn't up to scratch to replicate/be passed on genetically speaking. it makes me the bad egg of the family tree - well, me+the extra time. once I get past this and consider the recombination possibilities of the genetics, I'll probably be able to go to donor eggs - I know that's likely what we'll have to do if we don't have luck this year)

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  18. #320
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    I'm the same as you with the DE thing for me.
    Eggs are in an immature state in the ovary. Final meiosis does not take place til ovulation! This is a hugely energetic process. It is the final cell division where the number of chromosomes in the egg must reduce by half otherwise aneuploidies occur, like Down's syndrome. The spindle of the cell is the skeleton where all the chromosomes line up for splitting. The mitochondria fuel the splitting. At our age it goes wrong because the skeleton ie the spindle is disorganised and the mitochondria do not have enough energy to pull it apart evenly, leaving eggs with the wrong number of chromosomes. I've had many with only one damn mistake! And others with many mistakes! And one with no mistakes but still didn't make it. We're all just hanging out for one with no mistakes and enough energy left over for implantation, another energy sapping step.
    So theoretically you can still feed your eggs properly before they undergo those last few divisions.
    Last edited by Skyler; 28-07-2015 at 23:20. Reason: Made a mistake meant ovulation not fertilisation!

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