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  1. #771
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    Hi ladies, I've been laying low on this thread for a while, but I've since had a cancelled cycle due to poor responding, stayed on the pred and tried naturally, we fell pregnant but I miscarried yesterday which would have been 7weeks.
    I just have a quick question does anyone know the difference intralipids and prednisolone has on nk cells. Would having one without the other be ok or do they both act differently on the nk cells?
    Hope everyone is well, I read along every day and it's so good to see all the pregnant ladies doing so well, your little bubs will be here before you know it.
    To the other ladies still soldiering on, we WILL get there in the end 😊

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    Pauli77  (27-03-2015)

  3. #772
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    I am so sorry to hear miissalina. that's so sad. I have had this anxiety every day.

    I know someone personally who has very high active NK cell and didn't do intralipid but only clexane and prednisone. Almost due now. Intralipid is a trial. As far as I know, intralipid is more to calm NK cell. Prednisolone on other thing like high ANA (mainly the auto immune stuff).

  4. #773
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    Gosh I'm so sorry to hear miissalina.

    I rang and spoke to Gwenyth this morning and she said she would call me back today or later this evening- I'm still yet to hear back but I think that it's probably too late now and she won't call. I don't want to be that person forever calling and bugging her but I need to get the ball rolling!

    We have one embryo frozen here in regional Victoria and are moving to Sydney in June, so we want to transfer this embryo before we go but would prefer to have some sort of investigative tests done to see if this could be the reason for our previous failures!

    How long does it usually take for the blood test results to come back and a treatment plan to be worked out?


    Any help or info is greatly appreciated!

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    miissalina  (25-03-2015)

  6. #774
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    @bbhope as soon as I seen the positive pregnancy test at 8dpo my anxiety went through the roof I was constantly shaking, not wanting to eat it's was awful, my hcg levels for 3weeks straight were not doubling so I new something was wrong it just took a while for things to come to an end, we did get to see a heart beat at 6weeks although we were only measuring 5w3days. Seeing a heart beat for the first was amazing but it has made it all that much harder with the loss.
    Hopefully our next one will see my hcg sky rocketing and a healthy baby.
    I'm just a little turn whether to do intralipids again or not I've done it on 4transfers and all 4 I never got implantation, I only got implantation on transfers were I didn't use intralipids, no idea if it was pot luck or a coincidence , I've been trying to find how the two nk cell suppressants actually work and if they work differently but not having much luck.
    So happy to hear things r going smoothly for you 😊 once bub is earth side hopefully ur anxiety will go away although all the worrying about a new born will keep you on ur toes

  7. #775
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    Missalina, I'm so sorry about your loss. I love your positive attitude and its a good thing to know you can get pregnant naturally.
    Do you have the book? I'm sure it explains what Intralipids does.
    Do you take Clexane?

  8. #776
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    Miisalina sorry for your loss. I have done a few different cycles, Pred and clexane only BFN, pred, clexane and intralipids BFN, pred, clexane and IVIG BFP! Unfortunately even with the NK stuff there seems to be a lot of trial and error to get the right formula.

    Definitely get the testing rolling with Dr M, I can't remember how long everything takes but there is ALOT of waiting for appts, results, day 1 to come around etc... Worth waiting a couple of months rather than keep transferring embryos that may not stick

  9. #777
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    Hi ladies,
    Can anyone tell me the IVIG infusion rate? I think someone said they noted it down... I have an infusion next Thurs in Perth. They have ordered 15g but just wanted to double check how slow Dr M does it?

  10. #778
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    Hi ladies,

    It has been a while since I posted and I apologise in advance for this lengthy message but I want to let you know about an important development that has the potential if it goes ahead to help many women.

    Some of you may be aware that Dr Warren DeAmbrosis and Dr Mooring (QFG) travelled to New York recently to meet with Dr Braverman to discuss the possibility of setting a laboratory up here in Australia that would have the potential to do similar testing to what is being done currently via Reprosource.

    My understanding is that the information gathered during this visit will be discussed at the next Virtus Health Management Meeting where further decisions are likely to be made regarding the feasibility of this idea and I am sure the level of interest they think they would get from Australian patients would be part of this decision making process.

    If this laboratory goes ahead it has the potential to help many woman access testing here in Australia in a more timely and cost effective manner, without the added headaches that many of us have had to face sending blood overseas for testing. If this gets up and running then testing could occur in Australia in as little as 6 months. Wazza has suggested that if this is something that people feel strongly about then we should email the Qld Managing Director of Virtus Health, Steve Zeppia outlining our thoughts but more specifically the reasons why we think having a laboratory in Australia is important and the difficulties we face using the overseas labs, for example, expensive shipping costs, delays causing bloods not to be tested, issues regarding validity due to lengthy shipping time etc.

    I would love to see as many people get behind this as possible to try and make this happen. I am sure most of you agree that when it comes to Reproductive Immunology, Australia is miles behind other countries. If this goes ahead I am sure it will have huge implications for how Fertility Specialists in Australia view Reproductive Immunology issues. The flow on effect from that could be huge and hopefully will allow many woman who walk this soul destroying path behind us get a correct diagnosis and treatment sooner, allowing them to get their take home baby sooner. This may be our only opportunity to have some say in the future of Reproductive Immunology in Australia so it would be great if as many people can get behind this as possible and help make this happen.

    Remember ladies - power comes from numbers!!!

    Email: steve.zappia@qfg.com.au
    Last edited by Hope06; 27-03-2015 at 18:08.

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  12. #779
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    Hi scruffy, not the iVIG rate. But if some one knows how long DrM is doing it, you can calculate it. The rate is in ml/hr.

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    Scruffy  (27-03-2015)

  14. #780
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    Default High Natural Killer Cells #6

    Eveclo: test result takes 2w but depends on what u had it done. Have u made an appt with DrM. His wait time can be 3--4 w.

    Miisalina: I hope u have a closure now. It is so sad. To be honest, I don't know if intralipid works for me. I am using the kitchen sink approach. I just want it to work so I throw everything in. I only have ANA positive. No other known tested problem. I have a good embie for my first bfp and I wish ANA was tested back then. Second embie was slow growing. Day 6 grade A early blast. I started doing the immune protocol, clexane, pred, intralipid. BFP but hcg was so low that it wasn't viable to start with. This is my third transfer but second time using immune protocol. The big difference is that we r using donor this time. So I really have no idea if the first failed BFP is truly due to incompetent of the embie. I still feel sad for it as that's our bio child. I was tempted to skip intralipid this time around as I don't have other prob other than positive ANA and slightly (not much) elevated NK cell activity in uterus and we have presumably healthy sperms and eggs this time around. Since it is intestate ivf and have taken so much energy out of me, I just want to try my best. I would say that you can give it a try?


 

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