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  1. #221
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    @MGC Bertie - Yes, I'm really glad to have found this thread. It's so good to have others to 'talk' to about these issues. It's easy to feel overwhelmed otherwise.

    I don't know for sure that immune issues are my problem but I do think they're part of it. I suspect my adenomyosis, which may have developed since I had DD (not sure how long I've had it) is also a big problem - maybe the main one. I think I'm going to need IVF to do a long down regulation to help address it.

    I see you recently got a BFP? That is wonderful. Huge congrats
    Last edited by Lulubee; 08-01-2015 at 22:00.

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  3. #222
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    Quote Originally Posted by MGC Bertie View Post
    Little Ted.... yes, the chemist, your GP or medical centre will take it. Glad things are looking up for you. Gathering that the one bub is it? I think that will be the same for us, as it's taken us so long to get one BFP, that I couldn't imagine trying for a second one, as much as I actually always wanted three.

    Bbhope... my ANA is actually only 80 titre, but coupled with 6 other immune issues they all add up.

    Lulubee.... your story is similar to quite a few women, who had a first child naturally with no problems, and then developed immune issues after that. I don't know what they say is the reason why, though "stress" plays a factor in many other immune issues, such as Grave's Thyroid Disease.
    Congratulations! So glad to hear your happy news and very much hope this bub hangs on tight. Will keep on following til that precious little one 'pops' out.
    Our little miracle was our fourth. We had infertility for years before our first pumpkin finally got worked out then had two more close together to try and avoid my body going to far out of whack again. We were then devastated by the loss of an unplanned pregnancy a fair way in and it was left upon my shoulders. We decided that we would try again however went on to lose another 3 and 1.5 years later until they worked out what it was. Well, actually, the women on here worked out what it was before any bloods came back. I felt so defeated through the whole thing whilst at the same time knowing how blessed we were to have children already. I felt like such a crap mum the whole time as I was unable to function properly - this is one of my biggest regrets. Like you, if we had all these problems as well our infertility before having our first, then I don't know if I would be able to keep going back again.

    I'm very glad not to be poked and prodded for at least a couple of years!

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  5. #223
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    Quote Originally Posted by Little Ted View Post
    Congratulations! So glad to hear your happy news and very much hope this bub hangs on tight. Will keep on following til that precious little one 'pops' out.
    Our little miracle was our fourth. We had infertility for years before our first pumpkin finally got worked out then had two more close together to try and avoid my body going to far out of whack again. We were then devastated by the loss of an unplanned pregnancy a fair way in and it was left upon my shoulders. We decided that we would try again however went on to lose another 3 and 1.5 years later until they worked out what it was. Well, actually, the women on here worked out what it was before any bloods came back. I felt so defeated through the whole thing whilst at the same time knowing how blessed we were to have children already. I felt like such a crap mum the whole time as I was unable to function properly - this is one of my biggest regrets. Like you, if we had all these problems as well our infertility before having our first, then I don't know if I would be able to keep going back again.

    I'm very glad not to be poked and prodded for at least a couple of years!

    littleTed - was your issue high NK cells / immune stuff? I should just try and search back through the threads! I'm new to all this stuff and am desperately trying to figure it all out. I've just had my third miscarriage in a row and have been diagnosed with borderline nk cells. To be honest, I am slightly disappointed it wasn't a more clear diagnosis for me as I'm still not feeling confident we've found my issue.

  6. #224
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    Quote Originally Posted by Lulubee View Post
    littleTed - was your issue high NK cells / immune stuff? I should just try and search back through the threads! I'm new to all this stuff and am desperately trying to figure it all out. I've just had my third miscarriage in a row and have been diagnosed with borderline nk cells. To be honest, I am slightly disappointed it wasn't a more clear diagnosis for me as I'm still not feeling confident we've found my issue.
    I can fully understand your desperation and drive to figure it all out - I was there. I felt like a bit of a nutter but it seems to consume you somewhat. Particularly when the immune side of things is still relatively unknown by many physicians as it is relatively new and wasn't in their uni degree. Even then, many medical professionals still play down why the miscarriage happened saying "It's probably chromosomal/genetic as many are". I think if more were investigated then the statistics would be different.

    My problem was my immune system. I have Antinuclear antibodies of 640 and a clotting disorder called Factor V Leiden. When the placenta would go to take over my body would clot it off as it saw the baby as a foreign thing. I also had a TIA at the beginning of a twin pregnancy which would have been the FVL with the rise of oestrogen. My specialist just had me on clexane and aspirin, but I still had lots of bleeds and bed rest. I think the steroids would have been beneficial and may have prevented my body from starting more bleeds.

    I hope you find your answers soon, it's horrible living in limbo. I never got checked for nk cells as I had the paperwork sitting on my dresser for Dr M but found a local ob who had had one of Dr Ms patients and was happy to try that.

  7. #225
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    Quote Originally Posted by Little Ted View Post
    I can fully understand your desperation and drive to figure it all out - I was there. I felt like a bit of a nutter but it seems to consume you somewhat. Particularly when the immune side of things is still relatively unknown by many physicians as it is relatively new and wasn't in their uni degree. Even then, many medical professionals still play down why the miscarriage happened saying "It's probably chromosomal/genetic as many are". I think if more were investigated then the statistics would be different.

    My problem was my immune system. I have Antinuclear antibodies of 640 and a clotting disorder called Factor V Leiden. When the placenta would go to take over my body would clot it off as it saw the baby as a foreign thing. I also had a TIA at the beginning of a twin pregnancy which would have been the FVL with the rise of oestrogen. My specialist just had me on clexane and aspirin, but I still had lots of bleeds and bed rest. I think the steroids would have been beneficial and may have prevented my body from starting more bleeds.

    I hope you find your answers soon, it's horrible living in limbo. I never got checked for nk cells as I had the paperwork sitting on my dresser for Dr M but found a local ob who had had one of Dr Ms patients and was happy to try that.
    Thanks so much, Little Ted. I'm sure I'll eventually figure it out. But it's so nice that people understand what it's like. My DH is wonderful but doesn't always get it! And I too feel like a crazy woman at times! I'm so glad you worked everything out in the end. I have heard high ANA can be problematic. I'm not sure I've had mine checked but I guess mine would be raised as I have an autoimmune disease (Hashimoto's). The bleeding during pregnancy would have been so stressful, you poor thing. But you got there in the end - I think you recently had a bub? Huge congrats to you. Thanks so much for helping me out.

  8. #226
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    I can't figure out how to do a signature! Anyone know. Sorry, I'm a bit of a techno-wizz! NOT.

  9. #227
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    Lulubee - check out the Adenomyosis thread

    http://www.bubhub.com.au/community/f...agnosis/page14



    Quote Originally Posted by Lulubee View Post
    @MGC Bertie - Yes, I'm really glad to have found this thread. It's so good to have others to 'talk' to about these issues. It's easy to feel overwhelmed otherwise.

    I don't know for sure that immune issues are my problem but I do think they're part of it. I suspect my adenomyosis, which may have developed since I had DD (not sure how long I've had it) is also a big problem - maybe the main one. I think I'm going to need IVF to do a long down regulation to help address it.

    I see you recently got a BFP? That is wonderful. Huge congrats

  10. #228
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    Quote Originally Posted by sootymay View Post
    Lulubee - check out the Adenomyosis thread

    http://www.bubhub.com.au/community/f...agnosis/page14
    Thanks heaps sootymay. I'll check it out

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  12. #229
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    Quick question - for those who have had early miscarriages that are suspected to have been caused by immune issues, was your HCG rising normally? A characteristic of all three of my early losses (just over 5 weeks) was that my HCG was on the low side of normal and never quite doubled properly. Just wondering if that is in any way diagnostic of an immune cause or if it doesn't mean anything??

  13. #230
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    Welcome Lulubee,
    Sorry I can't help with the miscarriage stuff - getting the damn thing to implant is my problem! You are definitely a Immune candidate with your Hashimotos. I was told even a family history of autoimmune disorders puts you at risk (my sister has type I diabetes and hashimotos).
    To add a signature go to 'control panel' on the top left of your screen (if on a PC) and then click on 'edit signature'

    Just a quick question - does anyone know how to interpret the HLA matching results?? I have a page of random numbers but a heads up before speaking to Dr M on Weds would be good...


 

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