Oh Bertie, sending you lots of hugs, but hopefully it's just a late I planter.
As nidhulaine said, maybe you need a stronger immune protocol?
Mgcbertie, sorry to read the hpt was negative. As others have said there are MUCH stronger and more aggressive protocols you could try. You are on a pretty standard one by the sound of it. Ask Dr M to bring in the big guns. Hugs.
Thanks ladies for all your lovely thoughts. Todays HPT on 10dp5dt was also BFN, so fairly resigned now. I have the slightest hope that Monday might say something different, but fairly "over" it now. But thankyou all about using a more aggressive protocol. I did actually for this cycle say to Dr M that I want to use IVIG before the transfer, rather than Intrallipids, but he wouldn't do it, but said that he would do IVIG if I got a BFP. He didn't really give me a reason why, so I will definitely be bringing that up. Has anyone had IVIG before transfer? Nidhulaine.... I have also used progesterone pessaries or crinone cream (depending on what clinic I've been at) - is that what you mean by using "progesterone"? or something different from those forms? I will be asking (and researching) about Dexamethsone and Neupogen. I do wonder why Dr M didn't suggest either of those after the first 2 immune protocols didn't work? Glad that there are still some other things to try. Thanks heaps.
Hope you don’t mind if I join you all. I had a hysteroscopy and biopsy with Dr M last Monday. He was so lovely! Just waiting for the results and hopefully it will time ok for my next FET (transfer 5).
I did pred, clexane and doxy with Dr M last cycle with no luck. Apart from high blood NK cells and MTHFR mutation, we’re unexplained.
Dr M has mentioned Neupogen and IVIG as treatment possibilities.
Nidhulaine, I see you’re using Neupogen. Did you get it through Dr M? Gwyneth said it’s cheaper through some of the big pharmacies. How often do you use the Neupogen and do IVIG? Just trying to prepare myself for some possible costs!
Also, has anyone transferred more than 1 blastocyst? We’re contemplating it since we’ve now passed the magic ‘failed 3 cycles’ box that qualifies as for a double transfer. I’m sick of all of this but scared that all of medications and the risk of twins might add up to a big problem in pregnancy/birth etc. Dr M says go for it but my IVF Dr is reluctant and also doesn’t know I’m being treated by Dr M.
Too much to think about!
Good luck to everyone.
You buy Neupogen in 10 vials and u use the small insulin needs to draw it up and inject yourself. Good news is the needs are easier and smaller than clexene. You start about ovulation. Cost is around $1500 for 10 vials and on average u do 5 shots per vial so $1500 is 50 days supply. Dose of Neupogen depends on weight and ur immune system and u get bloods taken every 2 weeks. My dose changed quite a but. Neupogen is used for implantation and prevention of miscarriage. It can be purchased from Indian but the guy is very unreliable and it's really stressful. After dealing with him twice I now order it from a Sydney pharmacy.
I used intralipids on D7 but then had to have IVIG at week 5 because I had bleeding from week 4-5. I believe my body was trying to reject my embie and the IVIG fixed all that. I didn't do IVIG initially as I only did an iui so I didn't even have a definite embryo but it worked out. I do think uf only I had done IVIG first it might have been less stressful but IVIG is the most expensive treatment.
Mcg I didn't mention treatments like LIT and Humira as I have no personal experience of them and don't know if they are relevant to your immune issues but as I said before there are a lot more things to try.
Forgot to mention u take Neupogen till aprox 11 weeks of pregnancy although in the last week it's only every second day and IVIG is every 4 weeks and it's either $2,200 or $3,000 depending on your weight.
Thanks heaps for the info Nidhulaine
Nidhulaine.... thank you heaps for all that extra information. I think I have a lot to ask Dr M when I next see him. Will wait for the official BT result tmorrow (Mon) afternoon, and then will spend the afternoon on the phone making appointments left, right and centre. Big thanks, you are a wealth of information xx
MGC Bertie (26-05-2014)
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