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  1. #1
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    Default Should I change Clinics....Advice please

    Hi ladies, here's a quick summary of my history. My husband has retrograde ejaculation from an accident in his younger years. This means sperm goes back into his bladder instead of coming out. Only way for us to conceive is IVF/ICSI. There's absolutely nothing wrong with either of us which means we should conceive pretty quickly when doing IVF. My first cycle I conceived my son. 2 years later my first cycle I conceived my second son. All from my husbands frozen sperm all via the same clinic/fertility specialist. Then we decide last year in January to start again to achieve a third child. First cycle in February, I overstimulated badly and was hospitalised. 2 x 5 day blasto embryos had to be frozen as I was too unwell for transfer. Went back in April and had 1 transferred, this resulted in BFN. Went back in May for 1 transfer, this resulted in BFN. Fresh cycle started in May/June, fresh 5 day blasto transferred and 2 weeks later I'm pregnant. Went for my 6 weeks heartbeat scan with the IVF clinic to only find one big black empty sac. Devastated is an understatement. I had a D&C 1 week later. Fresh cycle started again in September, 1x blasto transferred = BFN. No frozen so fresh cycle again in December, 1 x blasto transferred = BFN. Currently been on a "break" from this "nightmare" since December. What am I doing? We so badly want a third child but it's just not happening and my clinic really isn't offering any answers or theories...just putting it down to my age! I'M 31 and my husband is 34. Last week I visited my referring GP who knows our history to get another referral to our IVF specialist to start the ball rolling again in March. She wasn't happy with the fact that my IVF specialist was putting it down to my age. She believes I should have been pregnant by now. She believes even in a game of chances/luck with IVF that I should have been pregnant by now with all of these rounds. She believes I need to change clinics......she says it takes a team to achieve a pregnancy at a clinic and somewhere along the line someone in the team is letting me down. Whether it be the embryologists, scientists whatever... I get minimum 20 eggs each cycle and always get a blasto.....I just can't get them to STICK! What do you guys think....should I look at going somewhere else? I'm so sorry for the long post.....

  2. #2
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    I would definitely try your luck somewhere else Gina - it does sound like someone is letting you down along the line. Also maybe try some supplements to improve egg quality as I would think you should be getting more fertilized and to blasto stage if you're getting 20+ eggs per cycle?

    Perhaps even see if you can try a day 3 transfer. Sometimes this just works better for some people rather than growing them out to day 5. Of course you can't guarantee that they will develop into a blasto and beyond in utero, but it can make a difference putting them back into their natural environment early. I had a day 3 transfer myself - the embryo was only 6 cells big at the time with minimal fragmentation, now we're counting down the days until we meet her!

    Other things to consider are using assisted hatching, embryo glue, or even something as simple as taking a low dose of aspirin in the TWW after transfer to aid implantation.

  3. #3
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    You are still 'young' in terms of your reproductive years , however quite a few years have passed since you started IVF and whatever testing you had done before your tried for DS1. For that reason repeating some standard bts such as thyroid function, AMH levels etc would be beneficial as things can change over the years and it might give you some more information to go on to tweak your protocol or show others areas of investigation. If your DH needs to have fresh sperm extracted having the quality retested would also be a good idea. If your clinic is unwilling to retest you then I would definitely consider changing.

    You have been incredibly fortunate to fall pregnant on 1st transfer with both of your children which I imagine is making things really frustrating now However, IVF isn't foolproof and sometimes it can take (quite) a few transfers before you hit the jackpot again. Good luck!

  4. #4
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    Thanks for your advice ladies. I do agree, I was thinking we should do a new collection of fresh sperm and a round of blood work again. Even though I'd recommended these things to my FS he doesn't seem to think I need to.


 

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