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  1. #1
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    Default 2 failed attempts...

    Hi. After some advice on what other people have done previously to get a successful IVF pregnancy!

    We've had 2 attempts both of which have failed.
    The first we had 8 eggs collected, 6 mature enough to fertilise & 5 which successfully fertilised. We then had 1 transferred, which did not take & the other 4 embryos did not make it to the freezing stage.
    We then tried again and had 6 eggs collected. We have been told that none of these fertilised. They say that there was nothing wrong with any of the eggs or the sperm. I'm not sure why this happened. Has anyone else had this happen? Someone said that it sounds like the clinic might have made a mistake? I'm not too sure about that at all though.

    Before we we try for third time lucky, I'm hoping to get some ideas and tips from other people on what they have done - diet wise, or acupuncture, massage, etc. open to any ideas!

    Cheers
    Pip

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    Hi Pip

    sorry to hear about your cycles so far.

    What are the issues that have lead you to ivf? MFI?

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    Pip39  (08-12-2013)

  4. #3
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    My age (I'm now 40) a low AMH of around 4 and my partner works away so not always home when he needs to be!! The embryologists keep saying it's just a numbers game & it will happen eventually... I'm thinking that there must be something else we can do!! There's nothing wrong with the sperm or egg quality!

  5. #4
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    Maybe ask if you can try an ICSI cycle. That way you know the sperm get into the eggs so your fertilisation rate might be better.

    I am now 8wks pregnant after our 3rd round of ICSI, we only got one in the freezer on the last cycle so I know how frustrating it is to get a low embryo success rate.

    As far as what we did - we used a different protocol on our third round, adjusted the meds (upped stims and added Lucrin) and used a different technique for the sperm injection to minimize damage to the eggs. I didn't use any herbs, acupuncture, special diet etc - in fact I was probably more stressed and less diligent about those things than in any other cycle.

    Good luck, I hope you get your BFP soon!

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    Pip39  (08-12-2013)

  7. #5
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    Thanks Cue! We've done ICSI with both of the cycles now as we figured it was the best way to ensure we got some fertilised eggs!! This cycle I was on 600iu puregon per day, then when I started the orgalutran they put me onto Lucrin as well for the rest of the cycle. I'm hoping it will be 3rd time lucky for us too! Congratulations on your 8 weeks!

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    Hmm maybe ask if they can use a process where they check for the spindle in the egg before injection. I can't remember what it's called but we used that option in our successful cycle and I think it helped with our embryos. Apparently if they hit the spindle when injecting the egg it can basically ruin the embryo. Are they doing that already?

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  10. #7
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    I haven't come across that one before so will look at that for the next round! Not sure if they have for the last 2 but will ask the question! Thanks again Cue!

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    Hi Pip

    I started at 40 and did 8 stim cycles. Like you I always got ok egg numbers and we did get many blasts during this time. One of my cycles failed to fertilise so after this we did icsi every time. I got pregnant first time but it took another 2 years for another cycle to work. By the fourth cycle my fs had me tested for everything and found that I had a moderate number of natural killer cells so she used steroids to lower my immune system. She then had my thyroid tested and there was a slight issue there too. From cycle 4 onwards I used high dose melatonin and vitamin e to help with my lining as it wasn't great. I took loads of supplements too. I've always done acupuncture and had a very high protein diet during my last cycle. I would highly recommend listening to the 'creating a family' podcasts on iTunes. They are really informative. Also a good place for information is the 'over 40 thread'.
    i do think its a numbers game too, but maybe a combination of all of the above assisted in this last cycle sticking. Another thing is she used calcium activator in the embryo solution this last time. Don't know if this made the embryo any stronger.

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  13. #9
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    No worries
    If they've done is before there will be an item for it on your invoice. I looked it up and it's called a polscope.
    Here's a link explains it a bit:
    http://www.ncbi.nlm.nih.gov/m/pubmed/12930570/
    Your FS may not think it will be worthwhile for you but there's no harm in asking.

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    Pip39  (09-12-2013)

  15. #10
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    Pip I am 100% for second opinions I have just got my BFP after changing fertility clinics city fertility to monash (wish id done it sooner) & my 3rd fertility specialist. It's good to have fresh eyes look over your case. I learnt more in my first meeting with FS at monash than I did my whole time at CFC. Also you don't have to feel obliged to transfer to a diff FS they have people coming in all the time for 2nd opinions. At the end of the day you need to go with your gut as you're the one going through the physical, emotional & financial side effects of ivf.


 

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