Dear Bub Hub members,
Are you a Mum-to-be with Type 1 Diabetes?
Are you a Dad-to-be with Type 1 Diabetes?
Do you have an older child with Type 1 Diabetes and a baby on the way?
If the answer to any of the above is "YES" then your family may be eligible to participate in ENDIA.
The ENDIA (Environmental Determinants of Islet Autoimmunity) study is looking into what causes Type 1 Diabetes in early childhood. Type 1 Diabetes in children is twice as common as it was 20 years ago. This is because our environment has changed and predisposed children are more likely to develop Type 1 Diabetes.
If we can understand exactly what in the environment is harmful or protective, we can develop strategies to prevent Type 1 Diabetes.
We believe that children are exposed to the environmental triggers that lead to immune attack on the insulin-producing cells, a stage is referred to as pre-clinical islet autoimmunity, very early in life – perhaps even before they are born. To investigate this, we are asking women who are pregnant and have Type 1 Diabetes themselves or have a family member with Type 1 Diabetes who would be a first-degree relative of the baby (i.e. the baby’s father or the baby’s older sibling) to consider participating.
Newborn babies less than 6-months old with a first-degree relative with Type 1 Diabetes are also eligible to join.
ENDIA researchers will be investigating the relationship between genes, the development of islet autoimmunity and Type 1 Diabetes, and a number of environmental factors including nutrition, exercise, body size, viral infections, and the microbiome – the term given to the trillions of microorganisms that call our bodies home.
Throughout Australia, we will follow 1,400 women in their pregnancies and the babies born from those pregnancies. The initial period of the study is three years; however, we hope to continue following the children into adolescence.
Recruitment is happening in SA, WA, Qld, NSW and Victoria.
ENDIA is an observational investigation and will not involve any study medications or treatments. If you would like more information about ENDIA and how your family may be involved please contact us at firstname.lastname@example.org.
Further information is also available on the ENDIA website at http://www.endia.org.au and Facebook page at https://www.facebook.com/endiastudy.
Thanks for your interest in finding the causes of Type 1 Diabetes!