Hi All, just looking for some advice and support. I have just had my 3rd round of IVF cancelled due to no fertilisation, despite getting 22 eggs and using ICSI. My nurse tells me the lab said they were only able to inject 2 eggs, as the others 'didn't look right' and these 2 didn't fertilise. Our first round of ivf also got cancelled, due to no fertilisation of 27 eggs, but we didn't use ICSI, so they were hoping this was the key. The lab did also say at this time that the eggs didn't look right. Our second cycle we didn't even make it to collection, as they had dropped my dose too much, hoping the issues were related to too many eggs=poor quality. I know feel at a loss as to what to do. I haven't yet had a chance to speak to my specialist, but given he didn't really have the answers the first time, I can't imagine he is going to know what went wrong this time. I'm wondering if anyone else has gone on to have successful fertilisation after failed fertilisation with ICSI? I am thinking our next option is to consider egg donor, but want to make sure we have as much information as possible before we go down this path. I do wonder if the medications could have had a bad effect on my eggs...has anyone heard of this happening before? I'm just feeling so hopeless and would love to hear from anyone who has been through a similar experience.