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  1. #711
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    Hi Ladies, Unfortunately our pregnancy is not progessing as it's a biochemical. I am devastated and can't understand why this is happening to me. I"m feeling really sorry for myself today so thought I would vent to you ladies. I had another blood test this morning so they can confirm that I will miscarry and hopefully avoid a D&C. Will find out later today. As you can imagine I'm pretty confused. My FS is telling me I just have to get back over there and try again as it's a good sign I got pregnant, yet the immunity doctor is telling me to wait as I need more tests and stronger drugs to prevent my body rejecting the pregnancy. It is so confusing when doctors have different views. I'm wondering if there is anyone out there who has had a similar history to me that could offer some advice. I have been through 15 years of IVF with 6 miscarriages, 2 ectopics, 2 stilborns, 2 sets of donors with only one biochemical pregnancy. We still have 6 frozen embryos in SA but we are now questioning our donors eggs. It's so hard to know if its your body or the embryos. Our donor has donated 4 x previously and all other recipients achieved a pregnancy the first time, but of course I don't know if those pregnancies resulted in a live birth. I believe the clinics should be telling us this information as if they all ended in biochemicals you would question the quality of her eggs. Anyway I'm ranting now. I'm just hoping there is someone out there who can offer me some hope. I'm questioning it all at the moment as I don't know what we should do next.

  2. #712
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    Abundance - I'm just a lurker here but couldn't not stop to give you a big warm hug you poor bugger. You've been through the wringer. My thoughts are with you and your DH.

    Em x

  3. #713
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    Oh Abundance - my heart is breaking for you, truly.
    I know words are so useless right now.
    Can I ask have they checked your blood type. This may be a no brainer - but I have a rhesus negative type, and after every miscarriage, IVF, D&C I have to have an Anti-D injection. This prevents me from rejecting any subsequent pregnancies based on blood type. The natural reaction is to reject any pregnancies which may take the fathers blood type.
    I cannot tell you HOW MANY times, I have had to ask for this jab.. you would think it would happen as a matter of procedure for all negative blood groups - we aren't that rare these days!!!!
    Is this the case for you... Im sure you would know, but just thought id ask, as sometimes my obs/gyn surgeons at IVF have forgotten about it!!

    you are in my thoughts xxxx

  4. #714
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    Abundance. I'm really sorry to hear of your news. You've been through so much and to go all this way and then have a loss is absolutely heartbreaking. Your FS is right though, it is a great sign that you fell pregnant. It could have just been that particular embryo wasn't quite strong enough to make it? My heart goes out to you. Take time to give yourself lots of extra TLC and pampering in the coming weeks.

    What I can tell you about the CFC process is that once the pregnancy is achieved, they rely totally on the recipient to keep them updated with test results and information relating to the pregnancy and then the birth. I've been filling out the form that they have given me with all the blood test results, scan info etc... but in 7 months time when my baby is due, it's up to me to send that form back to them. Just because you have no info, would not mean that the pregnancy did not reach full term. I have a 12 year old daughter - and your life is just a blur when that little one arrives. After going through the whole process, I think that if the CFC could obtain the information for you, they would. If you probe a little bit further you might get the answers you are seeking. They might even try to make contact with the recipient to follow up under the circumstances? Is there any way that you can PGD test your remaining embryos before putting them back?

    Thinking of you right now and hope that you can get some answers that help you to decide your next steps?

    xxx

  5. #715
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    Abundance - OMG.... I'm so sorry. I'm replying to your PM right now.

  6. #716
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    Abundance - I am so sorry. I can't even begin to imagine what you must be going through right now, only compounded for you by two differing medical opinions.

    I popped it in my last post, but there is a belief that a small dose of Naloxone may work. Only just very new to the fertility game. It is believe it or not an opioid blocker and was initially developed to be used for drug and alcohol dependence. That said, is now being used for immunological issues in fertility. It does however, block the body's ability to uptake opioids and a number of pain medications, so if you are to have an op, they recommend you cease it a couple of days prior.

    After all the pain you have been through, I hope you can find the emotional strength to have another go. It's easier said than done, but please don't beat yourself up. You did everything in your absolute power to give that little bubble the very best of opportunities and all the love in the world. Take care Hun xxx

  7. #717
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    Hi ladies, the clinic are trying to get some further information for me on my donors previous donations so hopefully there will be some answers. Apparently we have the best looking embryos they have ever seen so just goes to show numbers and the look of the embryo means nothing. As our embryos are 5 day blastocysts and have been frozen they can't do PGD. Apparently there are studies that show PGD doesn't improve pregnancy rates as a clinic in Europe only transferred PGD embryos and their pregnancy rates were no better than other clinics. My results were negative today so at least that's good news. I had really good chat with the clinic here and they have been very supportive and encouraging. They really believe there's a baby in this batch for me and are encouraging me to go back as soon as possible which is early Dec. Of course I would go tomorrow and my DH is also keen for me to get pregnant again so Dec it will be. Its only 6 weeks away so maybe we will be third time lucky! I'm having doubts about immune therapy this time but I have booked to see Dr M but he can't see me till end if Nov which will probably be too late for any further testing. You would think being a current Patient would give you some priority but no. I'm also getting a third opinion on immune therapy as I'm not sure i need it. If only I had a crystal ball to tell me what to do. In fact the clinic said to me that if they could say you will definitely get pregnant on the 5th cycle you would keep going. It's the uncertainty that makes you question things. This clinic specialise in overseas egg donation and claim it had only ever taken 4 cycles to get every patient pregnant. Even those with histories like mine. Unfortunately that doesn't come with a written guarantee I just hope I'm not going to be one of their statistics! They Do seem quite invested in getting me a positive result so hopefully it will work next time.

    helonweeks, I'm O- and donor is O+ and DH positive so I think we are OK. No Rhesus so not sure i need it.

  8. #718
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    Abundance - PGD only will tell you which embryos are genetically incorrect (and not on all chromosomes unfortunately) it doesn't improve pregnancy rates, but the hope is that you don't put back something that the body is likely to reject because of genetic problems down the track. My last IVF pregnancy in January this year miscarried because of a trisomy 10. Had I had had PGD testing prior to that cycle, the embryo would not have been put back.

    The horrible thing is that even if they put back a genetically perfect embryo the body can still reject it. There is just no guarantee with any of this... BUT you are on the path where you have THE best opportunity in achieving a pregnancy with young eggs and excellent medical advice and assistance. Your signature brought tears to my eyes when I read what you had been through - but don't give up.

    If I had a dollar for all the months in my life I spent trying not to get pregnant - to ever think I would have been in a predicament where I would do nearly anything to fall pregnant - well, I just wouldn't have believed it.

    It sounds like you have great support with your clinic. I have no doubt that they will help you explore every avenue before you go back in December.

  9. #719
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    Default All my love abundance

    Oh abundance I am so devasted for you and I know my tears don't help your pain and but it's just so unfair and so hard to pick yourself up and keep on going. I really feel your pain and truly believe you will be rewarded for your years of courage, determination, strength and bravery. But I am happy to hear you have got encouragement from the clinic and perfect embryos waiting for you, you sound like you have a great plan. The immune dilemma is such a hard one when you want to give all you have but have conflicting advice to follow.

  10. #720
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    Hi abundance, from what you say you are O rhesus negative!!!!
    if hubby is positive, and also donor then you MUST investigate this?????
    if you haven't had an Anti-d injection then this could be a contibutory factor (could - not definite).
    i have to have it after every gynae issue - I must have had at least 10-12 of them.
    If you haven't had the jab, and the bub is positive, then your body may be well going into attack mode. The anti-d is supposed to prevent the blood from mixing in either direction. (I think)! I don't want to claim to be yoda on this - but I certainly think its worth looking into, given your current situation?
    Can anyone help with this... Does anyone else have rhesus negative??
    Xxxx


 

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