Hi just wondered if there was anyone else who has just started a cycle of letrozole? I have PCOS and I am ttc no.2 after conceiving DD using FSH injections. My ob suggested trying letrozole this time and if not successful we will move into injections again down the line. I don't think my ob was expecting miracles from the drug as I had no reponse at all last time round to clomid but I have also read lots of good things about letrozole even for clomid resistant women so I am trying to be positive. I am on CD3 today and have just taken my first pill, hope to speak to others who are going through similar experiences.