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  1. #41
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    The stuff I have read has indicated that genetics do play a part in autoimmune disases (especially in those of the COnnective tissue group - Lupus, Sjogrens, RA etc)

    I know that with Coeliac there seems to be higher incidences of family members with RA and Type 1 diabetes. The have a little connection or something.
    (
    Having said that, your genetics seem really strong in relation to lupus - that sounds like my family and coeliac. Apparently there is a 1 in 22 chance of getting coealiac if you have a first degree relative with it but my mother, my grandfather (suspected) me and two of my kids. Just seems way higher than 1 in 22.

    I also have another two autoimmune diseases as well - one unidentified connective tissue diseases - possibly RA, or psoriatic arthritis (loads of symtpoms - but sero negative).

    I think both our stories show excatly what I was getting at before - that there seems to be some families more prone to these things than others.

    Quote Originally Posted by In My Stride View Post
    Lolz83 - I have SLE.

    My sister has it.

    My brother has it.

    My dad died from it at 49yrs.

    Aunts, uncles & cousins on BOTH sides have it (or have passed away from it) and they say it isn't hereditary.

    My Rhuemy used to work in the UK & treated some of my family there, I filled the gaps for her. My parents grew up across the street from one and other, went to the same school etc. they grew up in a poor area in post war Britain, many who grew up with them also have it & a myriad of other auto immune & cancers. Unusually high numbers. She's thinking now SLE could be environmental, was it something in the water? Where they given a dodgy vax as kids? anything is possible, I'm happy to pm you anything she discovers if you like, she's working with a few others gathering info at the moment like old medical records etc

  2. #42
    In My Stride's Avatar
    In My Stride is offline 3 babies, 2 businesses, 1 husband & a partridge in a pear tree
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    Quote Originally Posted by Witwicky View Post
    How ironic, I have actually been researching this very topic lately, out of interest.

    My son was diagnosed with Type 1 diabetes just a few months ago, at 12 months of age. We are selective vaxxers. He contracted a flu like virus prior to diagnosis, which is believed to have played a role in triggering the diabetes, although i'm not discounting other triggers. I don't doubt that he would have been diagnosed with diabetes at another point in time if something did not trigger it this year.

    His endocrinologist stated that more people are diagnosed with diabetes in winter than any other season due to viral triggers which are prevalent at that time of year (obviously referring to those who are genetically susceptible).

    It is my understanding that there are many possible triggers, and different triggers affect people differently, i.e.: one trigger may affect one person, but not the next.
    It's a bit like the chicken & the egg - was the diabetes sitting there ready to erupt & the virus & (mild) undetected diabetes pushed it over or did the diabetes only show up after, without a time machine to go back & test before we may never know? And . . . I guess the answer could be a for one person & b for another?

  3. #43
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    Quote Originally Posted by Witwicky View Post
    How ironic, I have actually been researching this very topic lately, out of interest.

    My son was diagnosed with Type 1 diabetes just a few months ago, at 12 months of age. We are selective vaxxers. He contracted a flu like virus prior to diagnosis, which is believed to have played a role in triggering the diabetes, although i'm not discounting other triggers. I don't doubt that he would have been diagnosed with diabetes at another point in time if something did not trigger it this year.

    His endocrinologist stated that more people are diagnosed with diabetes in winter than any other season due to viral triggers which are prevalent at that time of year (obviously referring to those who are genetically susceptible).

    It is my understanding that there are many possible triggers, and different triggers affect people differently, i.e.: one trigger may affect one person, but not the next.
    Diabetes in littlies is tough
    Our area has a high incidence of Diabetes Type 1 and there has been a spate recently brought on after the type of viral illness you described. The genetic predisposition with Diabetes is still there but I think you need to get the gene from both parents and then it has to have that trigger, 12 months is very young, most cases I've encountered have been around 4 years of age. I can't imagine having to do what's needed in regards to levels, exchanges and testing on a 1 year old, I'm sure it's been a huge learning curve for you.

  4. The Following 2 Users Say Thank You to Hootenanny For This Useful Post:

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  5. #44
    Witwicky's Avatar
    Witwicky is offline A closed mouth gathers no foot.
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    Quote Originally Posted by luvmyboys View Post
    Diabetes in littlies is tough
    Our area has a high incidence of Diabetes Type 1 and there has been a spate recently brought on after the type of viral illness you described. The genetic predisposition with Diabetes is still there but I think you need to get the gene from both parents and then it has to have that trigger, 12 months is very young, most cases I've encountered have been around 4 years of age. I can't imagine having to do what's needed in regards to levels, exchanges and testing on a 1 year old, I'm sure it's been a huge learning curve for you.
    Thanks, it has definitely been a big learning curve


 

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