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  1. #1
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    Default Low PAPP A

    I got my results back today from my 12 week NT scan and blood test. My obsterician is really happy with my results except for my PAPP A which he said is low (from memory I think he said .34). There really isn't that much information available on the Internet but what I have found is a little disturbing.

    I would really appreciated if anyone would like to tell me there story with low PAPP A.

    TIA

  2. #2
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    I also had low PAPP-A from my 10 week bloods as part of the first trimester screening. Mine was around .26 from memory. I am currently 30 weeks pregnant with my second baby and so far this baby has measured spot on for size and Im hoping it stays that way. PAPP-A is a protein produced by the placenta and it is an indicator of placenta function and how well proteins etc cross the placenta to nourish baby. There is some risk with low PAPP-A that the baby could have growth issues in the third trimester, so the doctors tend to do more growth scans and check placenta function and amniotic fluid levels in third trimester. There may be an increased risk of pre-eclampsia and early labour also. Having said that, there are many women with low PAPP-A who have no issues at all and have gone to full term with good sized babies. Dont worry yourself too much about it. I think we are probably victims of the over-assessed pregnancies that modern medicine has created. I guess you can look on the positive side that your doctor will monitor you more closely in third trimester to watch for any potential problems. I wish you all the best in your pregnancy.

  3. The Following 3 Users Say Thank You to HouseOfFun For This Useful Post:

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  4. #3
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    My PAPP-A came back low as well (0.33), but my obstetrician said this data was only one component of the total screening process, and at that stage didn't worry him at all, as the baby was doing well from all other signs.

    He also cautioned against consulting "Dr Google" too much, as this would just stress me out and affect bonding with the baby! There are so many horror stories out there on the Internet, I think it is best to let go, relax, and just trust your doctor.

    If you are really worried, bring it up at your next visit, tell him you're concerned about it, and ask him to explain why you should (or shouldn't) be concerned.

  5. #4
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    1BabyMama I could have written your post. I just got my nuchal result and my ratio is 1:25 due to Low Papp a... I'm terrified!!!

    Waiting for OB to call but seeing some healthy pregnancy stories is giving me some hope

  6. #5
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    I had low PAPP A also which brought the NT results down to 1:112. My OB recommended an amino which came back fine. I went onto to have a healthy lil girl weighing 3.8kgs.
    The OB also mentioned that this is quite common for IVF babies which ours was.

  7. #6
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    Hi there Our 12 week scan went well with low risk for all things although I did have a low count in my placenta for one of the proteins : low maternal serum Papp-a of .4 After reading your replies I feel much better that u can have healthy babies still after this result. Ours is an Ivf bubs as well. My Ob said I'm still low risk but they will need to watch the growth of our lil one in 3rd trimester. I stupidly googled too yesterday and panicked reading what it could mean. Positive thinking from now on! How are all your pregnancy"s going?

  8. #7
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    MY Papp A is .197 Its really really low.

    Waiting patiently for CVS results now. Were any of classified as high risk/delivered early because the placenta wasn't functioning?

  9. #8
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    HI Ladies

    My Papp-a is .17 and my tri 21 risk was 1 in 19 (28 years old). Just got the all clear from the amnio which i had 2 weeks ago. Doc said they will just keep an eye on the growth but most of the time all is well so try not to stress to much about it (i know easier said than done!!) My doc also said he often gets around .3 results and all is fine. Mine is just a bit lower but is an IVF pregnancy and for some reason there is a higher rate of low Papp-a with IVF?
    I found Dr Google quite reassuring as i found so many positive stories of successful full term babies with low papp-a like mine.

    Good luck on the tests x

  10. #9
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    Lightsaber - how are you travelling? I am 30 + 3 and up until now baby has been growing great! Except at my OB appt yesterday the ultrasound showed the baby's size has only grown 1 week in almost 4 weeks so i am booked in for a growth scan and doppler thingy next week so looks like the low Papp-A has reared it's ugly head! Good news is he has been growing at a good rate until now so while he hasnt grown much in the last 4 weeks he is still measuring 29 weeks and about 1.3kg due to docs estimation and he is pretty confident that even with slowed growth we should make it to at least 34 weeks.

    Would love to know how your bubs is going xxx

  11. #10
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    I had a low PAPP-A with my third pregnancy so I was scheduled to have regular growth scans during the last trimester. To cut a long story short, with every growth scan after 30 weeks, my baby's position on the percentile charts continued to drop. I was also taking belly photos every two weeks... and my belly from 32-36 weeks didn't really grow at all. My waters broke spontaneously when I was 37+1 and my daughter was delivered that night. She weighed only 5lbs, 50zs (about the size of a 34 weeker)... so she was a bit growth delayed, but thankfully VERY healthy. Surprising really, when we discovered at delivery that the placenta was about half the size that it should have been.


 

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