+ Reply to Thread
Page 1 of 3 123 LastLast
Results 1 to 10 of 28
  1. #1
    Join Date
    Jul 2011
    Location
    Hobart
    Posts
    183
    Thanks
    28
    Thanked
    17
    Reviews
    0

    Default Poor egg quality?

    Hi ladies hoping for some information on egg quality. I know I can have a test to determine egg reserve but what tests can be done to show if eggs are of poor quality?

    When I went to see FS for last FET he told me he had a donor for me I was devastated to say the least, I hadn't asked for donor eggs and didn't need to be asked on transfer day. I've gotten used to the idea now and know how difficult it can be to find a donor but I feel not enough has been done by FS to find any underlying problems. I'm 38 and have been doing ivf since I was 33 with unexplained infertility. Any advice?

  2. #2
    Join Date
    Aug 2009
    Location
    Brisbane, Queensland.
    Posts
    2,002
    Thanks
    260
    Thanked
    529
    Reviews
    4
    Achievements:Topaz Star - 500 postsAmber Star - 2,000 posts
    I can't really help much because I am in the same boat but only 28 yo. It's absolutely devastating because quite often you don't even have embies to transfer.

    My egg quality issues could perhaps be linked to my pcos but I am not really sure. I don't believe there's any tests they can do. Cycle wise, they can add dhea which I've just started. There is a whole thread on dhea here and many FS don't believe it makes a difference and won't prescribe it. But the amount of woman getting bfps after taking it is astounding.

    There is also a human growth hormone that you can take but it's very expensive, my FS said it would cost $2000 more per cycle to add it. He gave me some information sheets taken from medical journals and surprisingly the evidence is a bit hit and miss with that one, as to whether it helps egg quality or not. So I opted for the dhea and also taking coq10, royal jelly, vit b, c and e, fish oil and folate.

    Good luck and I will be eagerly watching this thread to see if anyone else has suggestions.

  3. The Following 2 Users Say Thank You to nicole83 For This Useful Post:

    luckychance29  (26-02-2012),wanabemum  (14-05-2012)

  4. #3
    Join Date
    Oct 2010
    Posts
    306
    Thanks
    33
    Thanked
    66
    Reviews
    0
    Hi Luckychance,

    I'm in the same boat too re: egg quality. Until December last year I was diagnosed as unexplained but I moved clinics and they found that I have insufficient progesterone which has been resolved with lots of crinone. However, the big problem seems to be egg quality. I get very few embryo's to blast stage. I have been to two clinics and both FS said that there is nothing you can do to improve egg quality. Having said that I have read on this forum about lots of girls having success with DHEA. I will bring this up with my FS but I read somewhere that's it's not good for women with PCOS and I don't think he will be keen to prescribe it to me.
    I have also tried royal jelly, coq10, traditional Chinese medicine. I read the following may improve egg quality too ACAI juice, vitamin C, vitamin B12, zinc, and wheat grass shots combined with a diet of no sugar, no alcohol and no processed foods. That's a lot of vitamins!
    At the moment we are waiting to do CGH testing which will determine if any of our embryo's are good. If not then I will need egg donation and have no idea where to begin.
    I really hope you get some answers and I'll also look closely at this thread too. Hang in there.

  5. The Following User Says Thank You to SummerShine For This Useful Post:

    luckychance29  (26-02-2012)

  6. #4
    Join Date
    Jul 2011
    Posts
    50
    Thanks
    0
    Thanked
    20
    Reviews
    0
    I too am in a similar situation. We have only done 2 ICSI cycles with lots of eggs collected from my 1 ovary (left ovary removed due to endo). 1st cycle we had 2 eggs fert and only 1 transferred as the other emb arrested. The 2nd cycle we only had 1 egg fertalise from 13 eggs and this emb had fragmentation.

    Both DH have been tested for karaotype, DNA fragmentation, cushings, adrenal hyperplasia anything really that could attribute to poor fertalisition. All tests came back fine.

    At our last FS appt we were told it was thought to be an egg quality issue and to consider donor eggs. No point continuing IVF if we keep having poor fertalistion results with nothing to freeze.

    We are about to attempt our 3rd and possible last round of ICSI. Our FS said we need to try a human growth injection from day 5 of our cycle for days. The HGH shot is called Saizen. At $200 a shot it is not cheap and adds and extra $1000 onto our cycle with nothing back from medicare as you need a script for this for the chemist as our clinic does not have the drug.

    The saizen has mixed reviews some women swear it has helped improve their fertalisation results others have said it did nothing.

    The other change in protocol for my cycle is instead of ovidrel for my trigger shot I will be using lucrin. Apparantely some women need this extra jab to signal their brain to release a hormone in our pituarity gland to help fertalise.

    We are willing to try this to achieve a better fertalisation outcome. If this does not improve then we will be told it is a waste of money to continue IVF using my eggs and if we wish to continue then donor eggs will be our option.

    sorry I couldn't offer any thing more than this, but it maybe worthwhile to suggest to your FS.

    I know a lot of women use DHEA and all the vitamins etc and acupunture but our FS has not suggested anything like this for me.

    Good luck!

  7. The Following 2 Users Say Thank You to Rivergirl For This Useful Post:

    luckychance29  (26-02-2012),wanabemum  (14-05-2012)

  8. #5
    Join Date
    Jul 2011
    Location
    Hobart
    Posts
    183
    Thanks
    28
    Thanked
    17
    Reviews
    0
    Thanks nicole, summershine & rivergirl for posting. FS has never reccommended anything to improve egg quality I was going ask about DHEA but I don't think he agrees with it. I never thought I had bad eggs I usually have around 20 eggs at pick up and have good fertisation with icsi. Last cycle I had 8 blastocysts and had 3 pregnancies from them (2 transfered each time) but all ended in early m/c. but FS never does anything different.

    Nicole you must have been so happy to have your DD after first cycle even though that doesn't take anything away from wanting another bubba. I hope the dhea works for you.

    Summershine I'm glad they found the progesterone problem for you, my clinic never tests for progesterone and doesn't do CGH testing. I also have tried TCM, acup, and so many vitamins! How do you feel about donor eggs if you need to use them?

    Rivergirl I agree wiyh you I would try anything to get the cycle to work I really don't care about the cost if the out come was good! May I ask how you feel if you need to use donor eggs?

    I have gotten used to the idea of using donor eggs now if that's what we need to do to get our bubba, but I already have 2 children from a previous relationship but DH doesn't have children. I hope your cycles work next time around and we all get our BFP.

  9. #6
    Join Date
    Aug 2009
    Location
    Brisbane, Queensland.
    Posts
    2,002
    Thanks
    260
    Thanked
    529
    Reviews
    4
    Achievements:Topaz Star - 500 postsAmber Star - 2,000 posts
    Quote Originally Posted by luckychance29 View Post
    Thanks nicole, summershine & rivergirl for posting. FS has never reccommended anything to improve egg quality I was going ask about DHEA but I don't think he agrees with it. I never thought I had bad eggs I usually have around 20 eggs at pick up and have good fertisation with icsi. Last cycle I had 8 blastocysts and had 3 pregnancies from them (2 transfered each time) but all ended in early m/c. but FS never does anything different.

    Nicole you must have been so happy to have your DD after first cycle even though that doesn't take anything away from wanting another bubba. I hope the dhea works for you.

    Summershine I'm glad they found the progesterone problem for you, my clinic never tests for progesterone and doesn't do CGH testing. I also have tried TCM, acup, and so many vitamins! How do you feel about donor eggs if you need to use them?

    Rivergirl I agree wiyh you I would try anything to get the cycle to work I really don't care about the cost if the out come was good! May I ask how you feel if you need to use donor eggs?

    I have gotten used to the idea of using donor eggs now if that's what we need to do to get our bubba, but I already have 2 children from a previous relationship but DH doesn't have children. I hope your cycles work next time around and we all get our BFP.
    Hun, I would be looking at getting a second opinion. If you get blastocysts and have been pregnant a whopping 3 times maybe it's just a progesterone issue like summershine. They really should be changing something or trying something new. Where are you located?

  10. The Following User Says Thank You to nicole83 For This Useful Post:

    luckychance29  (28-02-2012)

  11. #7
    Join Date
    Jul 2011
    Posts
    104
    Thanks
    15
    Thanked
    19
    Reviews
    0
    Hi there

    I too have egg problems - the last time I saw my FS she reminded me that we are dealing with 'significantly' bad eggs. As I understand it there is no test - the reason I've been diagnosed with poor quality eggs is because I have very low fertilisation rates and poor embryo quality - DH's sperm is fine.

    I am lucky enough to know someone who is willing to be my egg donor and although I was totally against the idea when my FS first brought it up, I am now comfortable with it. I wrote about this in another post last year - I've just copied and pasted it below:

    ..............................................

    I'm considering egg donation on advice from our FS. We had 13 eggs in our first cycle, four fertilised and none made it to blastocyst. On our second cylce we had 15 eggs, ICSI was done on 13 and only four fertilised. On transfer day, one embryo was 'showing signs' of moving to blastocyst so it was transferred. Unfortunately, we haven't been able to get any answers to what our probem is. FS is pretty certain that its an egg issue. DH is getting a DNA fragmentation test in the next couple of days just to make sure.

    We will try a few more IVF cycles and we are also doing all we can to increase egg quality, but if we can't make any viable embryos then we are not prepared for IVF to consume the next five years of our lives. I think, for our own mental stability, we need to be realistic. Being open to the idea of egg donation now means that if we ever have to take that route, we will be prepared. We want to be parents, we are in a great position to be parents, and whether we have a biological child, a child via a donor or an adopted child will be so happy.

    Being open to the idea of egg donation and adoption is also a bit of a coping strategy. After going through this I am pretty confident in saying that I'm a positive person - not always optimistic but always thinking that its not that bad, we can use a donor or we can adopt (although that will consume the next few years of our lives!).

    .................................................. ........
    My husband and I knew after our very first IVF cycle that we didn't want this to take over the next decade of our lives. Sounds like you might need to move IVF clinics and then decide on how long you want to continue trying with your own eggs.

  12. The Following User Says Thank You to Rittzy For This Useful Post:

    luckychance29  (28-02-2012)

  13. #8
    Join Date
    Jan 2011
    Posts
    766
    Thanks
    24
    Thanked
    45
    Reviews
    0
    Achievements:Topaz Star - 500 posts
    Luckychance29- I can't really be a lot of help regarding the egg quality issues, but I just wanted to ask have you had any other testing done? Have you and DH had a karyotype blood test?
    You seem to get a lot of blastocysts for someone with apparent egg quality issues. As someone else suggested, it could be something else entirely. I only bring up the karyotype test as an example as it answered our 'unexplained infertility' issues and a lot of FS's never suggest doing it (the chromosome issue that DH has can cause infertility issues as well as recurrent miscarriage but there is no other way of knowing he has it as otherwise he is perfectly normal).
    Good luck

  14. The Following User Says Thank You to vesper For This Useful Post:

    luckychance29  (28-02-2012)

  15. #9
    Join Date
    Oct 2010
    Posts
    306
    Thanks
    33
    Thanked
    66
    Reviews
    0
    Luckychance - I agree with Nicole I think I would get a second opinion too. You do seem to get a lot to blast stage and have been pregnant three times. If I didn't get a second opinion my luteal phase defect would never have been picked up and I would have wasted more $ cycles that were never going to work. A different FS might have a fresh approach and be looking for different things. There are lots of tests you can try - natural killer cells, progesterone, chromosome abnormalities. I think it's worth a shot.

    As for egg donation I'm very open to it. Ideally it would be nice if things had of worked out how they are suppose to but I don't have a real desire to have a genetic link to a child. I would like to experience pregnancy and it will be nice that DH will have a genetic link but I just want to be a mum - however that comes about. My biggest problem with donation is getting a donor - I have two beautiful friends that have offered but one is too old and the other has not even started a family yet - so both unsuitable. I am looking at overseas programs at the moment.

    Btmac - It's interesting that they told you have PCO and not PCOS. My only symptom of PCOS is polycystic ovaries - I don't have a weight problem and I ovulate regularly but they still write in my file PCOS - I really think I'm PCO (not that it makes much difference I guess).
    That's great about your embryo's and so many! I really hope this cycle works for you. I think I will follow your protocol. How long did you to it for before this transfer? Thanks so much for your post.

  16. The Following User Says Thank You to SummerShine For This Useful Post:

    luckychance29  (29-02-2012)

  17. #10
    Green Mum to be's Avatar
    Green Mum to be is offline Just one baby pretty pretty please with sprinkles and a cherry on top
    Join Date
    Jan 2009
    Location
    A-town, South Australia
    Posts
    465
    Thanks
    56
    Thanked
    86
    Reviews
    0
    Hi LuckyChance,

    I was initially unexplained, and they even thought it could be the donor we were using at home. I had two early miscarriages and had to FIGHT to get a referrel to the FS.

    My AMH was 14.1 so low for my age but still within normal limits.

    First ICSI I got decent results 9 eggs, 6 fert, 1 trans, 2 frozen then both the frozen defrosted and no pregnancy.

    Second ICSI we had 8 eggs, 3 fert, 1 transferred. At this stage the FS told us that it looked 'grim' and that with the decreasing numbers there was an issue with my quality. I asked about DHEA and he too refused, apparently hit and miss with the success and the clinic had decided they wouldn't go down that road.

    Third ICSI 10 eggs, no fertilisation. I was 29. He wouldn't recommend continuing with my eggs as there was a quality issue and chances are this would happen again and again. In fact, it would be a 'miracle' if they could get me pregnant with my eggs.

    I took from this that there was no test to see egg quality but it is rather taken as an indication of your previous cycles.

    I would have had a second opinion but we couldn't find a viable clinic and after getting some legal advice we found out that we could use my partners eggs in me. Initially we were told that we couldn't do this.

    After the long post, I believe that egg quality is an indication based on previous results. I would recommend a second opinion just in case.

    However, you need to think about the importance of the biological connection, money, time etc etc and find a point, if there is one when you are willing to move onto donor eggs.

    My TTC diary talks a lot about the process i went through grieving the biological connection and ultimately making the decision to move in this direction.

  18. The Following User Says Thank You to Green Mum to be For This Useful Post:

    luckychance29  (29-02-2012)


 

Similar Threads

  1. Huggies product change-now very poor quality
    By joclare84 in forum Nappy Topics & Nappy Rash
    Replies: 55
    Last Post: 30-07-2012, 00:03
  2. Poor quality blastocyst
    By tikigirl in forum pregnancy and babies through IVF
    Replies: 4
    Last Post: 19-04-2012, 21:12
  3. Ugh wish I bought quality!
    By jenrose in forum Pregnancy & Birth General Chat
    Replies: 28
    Last Post: 13-12-2011, 17:12

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
free weekly newsletters | sign up now!
who are these people who write great posts? meet our hubbub authors!
Learn how you can contribute to the hubbub!

reviews
learn how you can become a reviewer!

competitions

forum - chatting now
christmas gift guidesee all Red Stocking
Pyjamas.com.au
With so many gorgeous brands and styles for every season, our pyjamas, nighties, robes, sleepsuits and sleeping bags are lovely for lights out and perfect for lazy days. Get 10% off first order using code bubhub. Be quick offer ends 31/12/16.
sales & new stuffsee all
True Fairies
True Fairies is the first interactive website where children can engage and speak with a real fairy through the unique webcam fairy portal. Each session is tailored to the child, and is filled with enchantment and magic.
Visit website to find out more!
featured supporter
Life Fertility
Life Fertility Clinic is a boutique fertility clinic located in Spring Hill, Brisbane. Our dedicated fertility and IVF specialists offer professional, holistic, personalised options for the treatment of each patient’s specific needs.
gotcha
X

Pregnant for the first-time?

Not sure where to start? We can help!

Our Insider Programs for pregnancy first-timers will lead you step-by-step through the 14 Pregnancy Must Dos!