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  1. #1
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    Lightbulb Long term IVF warriors......PLEASE HELP?

    Hello girls and guys,

    Today has not been my finest day....EPU only one egg despite two follicles (and yes, I know some of you have had none...please don't hold my current self absorption against me!). My husband's car is broken down and in to be fixed and on the way to EPU, a kind man in a next door car pointed out to us that I have no brake lights....

    I was advised by the kind lady Vesper to post on the IVF warriors site but I though maybe a separate thread would help keep everyone's reading down? Please let me know if that Isn't helpful and I will post on the original thread.

    This was cycle 13 for me ICSI for all (hubbie sperm fine). I have severe endo and have had 50% of my cycles cancelled due to this bizarre reaction of spontaneous ovulation. It has occurred on both down reg and antagonist cycles.

    Can anyone help? Has anyone else heard of or had similar problems.

    Also, as longtermers battlers, if anyone could reply with a list of what they think are TRULY helpful adjuncts to improve egg and embryo quality, I would be grateful. I keep hearing and reading about zinc, co10, Shea, prednisalone, aspirin etc for immune stuff and other things but I'm not really sure (given my tendency to bizarre reactions and hypersensitive, what is worth even considering. I'm a medical professional myself (not Gynae) and I'm currently having acupuncture if you have read any of my other threads....but willing to consider things if people feel they really could swear by some additions to their treatments.

    Good luck to you all at your various stages.

    Will be really pleased to hear any replies,

    X giohara

  2. #2
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    Giohara,
    Firstly, can you shed a bit more light on what additional testing you have had as this would influence what others might suggest i.e. have you been tested for immune issues like ANA's, NK cells, blood clotting disorders, ovarian reserve (AMH), had karyotyping for both you and your DH? Due to the severe endo I assume you have had a laparoscopy or 2 to remove endo & check for any structural issues at the same time? Sorry I don't know anything about the spontaneous ovulation, but I'm curious how this happens if they are tracking you closely with bts and scans?

    As for improving egg quality lots of women here have had success with DHEA, some with Saizen (human growth hormone), and from my own research & experience royal jelly, fish oil, & CoQ10 is definitely worth taking. A consult with a naturopath who specialises in fertility could definitely help with tailoring something to your specific needs. What city are you in, someone may be able to give you a recommendation if you like?

    Hoping your egg fertilises beautifully overnight and this is your time to get off the rollercoaster

  3. #3
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    Starfish,

    Thank you for your kind wishes.

    The truth is I haven't had many of the tests you talk about. No AMH though have been thinking of this since someone on another thread suggested it.

    A naturopath is a good idea.

    Can you tell me what royal jelly is and how you take it please?

    Thanks for your fast answer.

    Hope those sleepy blastocysts wake up and implant for you soon.

    Giohara x

  4. #4
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    Hopefully you might not need to do this. for your one egg.

    My suggestion is you collect all the details of all your cycles and do an analysis, what worked, what didn't, when did the cancelled cycles occur. I did a spreadsheet, what type of cycles, dosages of drugs, no. of eggs, EPU timing, mature eggs ratio, fertilisation rate, blastocyst/transferable embryo ratio, outcome, no of frosties.

    Secondly, maybe a bit of extra investigations as Starfish has suggested. Just to cover all your bases since you've already done enough cycles to warrant it.

    Thirdly, it might pay to get a second opinion from another FS who's experienced at older women and multiple failures. Just to look at it from another angle.

    Fourthly, have you started considering donor eggs? Do you have a younger sister/cousin who might be able to help out? (before she gets too old to donate herself).

    Fifthly, it probably won't hurt to give some of the "extras" eg. DHEA, growth hormone, melatonin, fish oil, royal jelly, co Q 10, zinc, and other supplements a try. Throw it all in as we say.

    Finally, can I point out that you do have to step on the pedal as you're running out of biological clock time? (sorry to be blunt)
    Last edited by Frostysmum; 05-02-2012 at 07:54.

  5. #5
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    Giohara,
    There is an absolute wealth of info here on just about every type of protocol/drug regime/ complementary therapy you can imagine! If you use the search function you should be able to find a lot of this info.

    Here is one on Royal Jelly: http://www.bubhub.com.au/community/f...or-egg-quality

    In terms of further testing Eternal Optimist wrote a really fantastic and detailed response about what to ask your FS after an unsuccessful cycle. It is here:
    http://www.bubhub.com.au/community/f...k-our-FS-to-do

    I agree with Frosty that after 13 cycles your FS really needs to be doing something very proactive for you or I would be getting another opinion.

    Last edited by Starf1sh; 05-02-2012 at 08:20.

  6. #6
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    Starfish and frostysmum, thank you.

    I have actually sought a couple of opinions although just over the phone rather than in person consultations. I did do my own analysis of the cycles and in fairness to my equally frustrated FS, so has he been doing. I do believe he is doing his best to help me and genuinely is lost as to where to go from here. I think the fact that I too, am a doctor, is very intimidating for him where he desperately wants to see me succeed.

    I will take on board though all your suggestions about the additives....they can't hurt.

    Lastly, thank you for suggesting the search function and for adding those links for me. Amazing list of questions.

    I am an only child with no friends of an appropriate age to donate eggs but yes, of course I am considering that as a next option. I am acutely aware that time is of the essence. No need to apologies....blunt is good here.

    Will keep you posted as to this cycle. Nervous for tomorrow but not much I can do except try to stay positive and take things one day at a time.

    Thanks agin for all the benefits of your wise words.

    X giohara


 

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