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    SpecialPatrolGroup is offline T-rex is cranky until she gets her coffee.
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    Default Donor BM and baby's immunity

    I was just reading the thread about a poor lady who died while having her bub and that they have been inundated with donor BM, which is great for bubs. I got to thinking about babies that receive BM from many donors and I am wondering, would these babies have a better, or more *broad spectrum* immune system because of their exposure to antibodies from multiple sources? Does that question even make sense?

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    Interesting question!

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    SpecialPatrolGroup is offline T-rex is cranky until she gets her coffee.
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    Bumping....just in case someone out there knows.

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    Yup, I'm pretty sure it would. There is also the infection risk though, so potential donors would have to be screened I would imagine.

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    Yeah, I figured that theoretically it would have that effect, but wondered if that sort of information had ever been captured in any longitudinal studies or similar. I guess that it would be a fairly small sample group so it may not be conclusive. I started to google but haven't come up with anything yet.

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    Interesting! I would think so.

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    SpecialPatrolGroup is offline T-rex is cranky until she gets her coffee.
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    Bumping...jic.

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    BM would contain antibodies and antigens of what the expressor/donor has in their circulatory system.

    For example. I have had chickenpox as a child as well as been vaccinated for Hep A & B, Diphtheria, Tetanus and Polio. So I would have antibodies for all of these in trace amounts in my system. Also - if I eat nuts/eggs/dairy/gluten etc I would have these antigens in my system too. They would get transferred in small amounts into the breast milk. Whilst antigens can pass through the placenta - antibodies dont. So you can partially 'de-sensitize' your bub to foods when pregnant by eating a wide range of foods as they do not have an immune system yet to revolt against it.


    In summary - my bub has not responded to antigens (genetics and piggy behaviour during pregnancy) and has antibodies for Hep B etc in small quantities. But if I was to get a bout of Hep A for any reason - my body would produce antibodies to Hep A in huge amounts and some would transfer to bub protecting them from getting sick.

  9. The Following User Says Thank You to Rose&Aurelia&Hannah For This Useful Post:

    SpecialPatrolGroup  (02-02-2012)


 

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