I am hoping someone in bubhub world can help me out. We are undergoing IVF/ICSI to conceive our second child with very little success.
After our most recent round of IVF that was an unmitigated disaster (of 19 eggs only blastocyst could be transferred and resulted in another miscarriage) my FS has sent my DP of for analysis of his sperm for DNA fragmentation. We have had 5 miscarriages (at various stages before 12 weeks), 4 BFN and have one miracle two year old. Our last cycle clearly indicated that most of our embryos arrest on Day 3. I have been tested for everything under the sun and no issues have been identified.
I have done some reading in DNA fragmentation and it seems to describe our situation and failures perfectly. I guess I'm hoping for some success stories from couples that have bad DNA fragmentation and what approach was taken for treatment - varicocele surgery, oral anti-oxidents, TESA or any other approach. DP has an appointment next week.
I am not opposed to using a sperm donor but would like to explore all options before going down that path.
Any advice, information or thoughts would be greatly appreciated.