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  1. #1261
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    Starfish – Just the most wonderful result and 3 in the freezer – fantastic, what a great team! Hope you are feeling good and little embryo is snuggling in nicely!

    Out of interest what are vacuoles?? Sounds like the hi-mag was a great help!

    Hope you have some nice things planned for this tww

    Slinky – so glad things are going fantastically, that’s an awesome result having 4 embryos on day 3 – keeping everything crossed they power onwards!!


    Fiona – Huge Congratulations to you and your DH, what wonderful news!!




    Swede – So sorry to hear your news. I agree with Slinky, hopes its a sign of your fertility post baby – doesn’t make this disappointment any easier though. Hugs to you

    Spot – sorry for the loss of your precious dog. Good luck for your upcoming cycle

    T42 – 15 weeks is fantastic – how lovely it must be to see your little bubba each visit after the stress you have been through. These IVF bubs are such precious miracles.

    Millie – some for your Christmas miracle!

    Mum4nay - hope the move is going well

  2. #1262
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    Pink, re: the vacuoles, this is cut and paste from info I posted on the long termers thread. There is always something new to learn hey!?

    "In regards to MFI and the vacuoles this is the info I got from Prof Illingsworth today about our situation. Apparently a sperm sample can appear normal looking at the basic parameters, for example, my DH's had normal count, motility etc, so-so morphology and his DNA fragmentation when last tested was in the excellent range < 15% (as measured by tests such as SCSA or TUNEL assay). A sample can also appear good on a DNA frag test but still have a high number of vacuoles (holes in the head of the sperm which are thought to be caused by DNA damage) which can only be detected with high magnification. As I said DH's sample showed 95% had vacuoles!! An 'acceptable' level is 30-40% so I really pity the poor scientist who had to wade through that sample and pick out the few unaffected spermies!

    DH has been quite disconcerted to discover this and in some ways we might've been better off to go with digital high magnification rather than PGD for our last cycle which were the 2 options we were weighing up at the time. However the technology was not available together at the same lab (and the difference in $$ is massive between these 2 options). Regardless, there is no point in looking back we made the best decision we could at the time and we could torture ourselves endlessly with the 'what if's?'. However, my learning from this, where there are mutual fertility issues I would continue to push FS to keep sperm quality issues firmly in mind"
    I am sooooo stoked to see you only have 13 weeks to go wow that will fly by! Are you feeling settled in your new place yet?

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    Mom2TwoDSs  (21-11-2011)

  4. #1263
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    Slinky, what amazing embies you and your DH can make!!! Hoping you will have a few to choose from tomorrow and looking forward to having a PUPO mate!!

    Millie, love your comment re: the snow sleep I'm thinking you will be getting the best xmas present ever this year!!

  5. #1264
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    "In regards to MFI and the vacuoles this is the info I got from Prof Illingsworth today about our situation. Apparently a sperm sample can appear normal looking at the basic parameters, for example, my DH's had normal count, motility etc, so-so morphology and his DNA fragmentation when last tested was in the excellent range < 15% (as measured by tests such as SCSA or TUNEL assay). A sample can also appear good on a DNA frag test but still have a high number of vacuoles (holes in the head of the sperm which are thought to be caused by DNA damage) which can only be detected with high magnification. As I said DH's sample showed 95% had vacuoles!! An 'acceptable' level is 30-40% so I really pity the poor scientist who had to wade through that sample and pick out the few unaffected spermies!
    Starfish, my DH is diagnosed with MFI as well, low count<5mill, poor morphology and low motilty. Over here in Melbourne our facility only has HA binding to select mature sperm. Have you tried that before?

    I have seen the digital mag on tele and we so wanted to use that technology but they only has it in Sydney. This round with your high quality blasts, i see you used your sis' eggs and digital mag on DH's sperm, are you 100% sure that digital mag of DH's sperm is the magic to creating the high quality blast, or do you think your sis' eggs is the one? Or you reckon both factors? Can I ask why you didnt use your own eggs this round since you did get pregnant 4 times with your own?

    Thanks for sharing...we have had 3 IVF witht ICSI but all our embie quality suck . I really dont know if it is due to my eggs or due to DH's sperm condition. We thought HA binding will solve the problem but doesnt seem to. It is so discouraging. I am thinking of getting DH to do the sperm fragmentation test (SCSA) since this round is BFN again.

    Is it possible to travel to Sydney for egg retrieval and sperm magnification process, yet do the stim and scans here in Melbourne? I am just wondering...feeling desperate already.

  6. #1265
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    Mom, whilst I appreciate you are very distressed by your situation & are seeking answers, I think it is very important to be mindful of the manner in which you ask questions, particularly of people you have never 'met' or interacted with before.

    I would suggest contacting IVFA Westmead clinic directly & asking them about the possibility of accessing this technology from interstate. All the best.

  7. #1266
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    Starfish, sorry I dont mean to be intrusive or anything like that ....we are all here to help one another and that is my intention as well. I happened to stumble upon your post. I am sorry if my questions made you feel this way and it is perfecty alright if you would not like to share. Sending you lots of in your 2ww. Thanks!

  8. #1267
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    Starfish, just a quick note to say that I am still sending snuggly vibes to your emby! Also re your post on the magnification issue, obviously I haven't been through what you have been through and don't understand the technical side at all so I can't comment on that, but from my own experience in IVF, the technology is changing so incredibly rapidly (although unfortunately, our budgets aren't changing with it!!!) that there will ALWAYS be lingering questions of should we have tried X, or tried Y - irrespective of what one's infertility issue is. All of us in this infertility boat are at once incredibly lucky and incredibly unlucky - lucky that we live in a time where there is technology like IVF to help us fulfil our dreams, but unlucky in that it is all in the main still very experimental - we are all of us on the cutting edge here. I think in a few years there will be technology available that will screen all embryos for chromosomal defects - and scientists will probably unravel the mysteries around egg quality and implantation. That's all great - but we have to make our families today. So we have to trust our instincts about what is right and make our peace with the choices we have made. As I have posted on this thread many times, I regret some of the choices I made (I went along with the first FS for far longer than I should have when his approach was clearly failing) BUT while this might sound a bit metaphysical, I do believe that I went through everything for a reason, that it has made me a more patient and forgiving person, and I will cherish this baby with every fibre of my being if I manage to hold it until viability . That's just my perspective on it all anyway. Anyway lovely I know you are in that crazy time, the 2WW - I hope you have some nice distractions on hand and that DH is spoiling you, and know that everybody on this thread is hoping like crazy that this is the one to give you a sticky, healthy BFP.

    Slinky, hope those embies are powering on! Sending positive vibes for strong and healthy blastocysts Also hope you are continuing to recover well from EPU.

    Swede, I was so sad to read your news. I know the excitement of both an unexpected BFP and the sorrow of early miscarriage and my heart goes out to you I do agree very strongly with what others have said that you can take something positive out of this sadness, that your uterus is clearly very receptive to embryos and when the right one comes along all will be well.

    Pink, its great to log on to this thread and to see your ticker bouncing along - not long to go now! Hope you are feeling well!

    Mum4Nay, Hope all is going well with you and your little boy miracles - big and small!

    Millie, hoping that Wazza will give you a Christmas miracle

    Fiona, hope that precious pregnancy is steaming along with everything happening just as it should

    Mom2OneDS, it might be more appropriate to start a thread with these queries so that people can choose whether or not to respond. I wish you every success with your fertility journey.

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  10. #1268
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    Tryingfortwo, thanks! Yes I just did.

  11. #1269
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    Hi ladies

    starfish, my PUPO-lady-in-crime - hope you are trundling along OK with everything.

    trying, pinkB, starfish - thanks for all your kind thoughts and a quick update on us. We have one beautiful expanded blastie on board (it did look amazing - FS and embryologist were both v pleased) and another blastie that will be frozen this afternoon. In addition, the other two are also looking very good, doing all the right things at this stage just a little slower. So they'll keep an eye on them over the next 24 hours and decide whether one or both of them is/are good enough to freeze.

    DH and I had a lot of serious talks over the weekend. We had initially indicated on our consent that we wanted to transfer 2. I'd been thinking this is all we'd be lucky enough to get out of this cycle and it was a way of not having any frozen and drawing a line under this chapter of our lives. We admitted to ourselves over the weekend that it is entirely possible to conceive twins from two (duh!!!) and agreed that that would be too much for us. After all, we're not Mary and Fred or Angelina and Brad, with access to countless nannies etc. So on arriving at the clinic this morning I told FS we'd only be doing one and she was quite relieved - said that because the two front runners are both so good, she felt nervous about transferring both and was going to try to convince us to do just one. So that's where we've ended up and I'm very comfortable with the decision. Of course, we will now have at least one frozen one, but what we do with it will be a decision for another day. FS suggested we could keep it on ice and try using it half way through our time in Japan, assuming this current one doesn't work. Even though I'd be 41-42, it would be using the embie of a 39yo. Anyway, we will see. For now we've made the decision to freeze however many we get and will think about it again depending on what happens.

    I've had acupuncture this morning and will try and do some high quality resting for the next few hours (not my strong point...).

    Sorry for the long post. Huge things to think about!!!

    Hope everyone is doing really well

  12. #1270
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    Quote Originally Posted by slinkymalinki View Post
    After all, we're not Mary and Fred or Angelina and Brad, with access to countless nannies etc.


    Slinky, thanks so much for that PUPO buddy, got a belly laugh from that one!! Your embie sounds AMAZING and the reasoning of yourself, DH and your FS very sound, what a team!!! Also what a great 'back up' plan, from a slow start this cycle has certainly turned out to be a winner! Rest up lovely, will check up on you over the week!

    Trying, You are just so incredible and wise. Once again everything you said has deeply resonated with me and been a balm on what is a wonderful situation but still emotive topic. Boy your DH is lucky to have you, please tell him I said so!!

    Pink,

    Swede, sending more

    AFM, I think I was distracted last week by basking in the joy of actually getting a transfer and then our little snow family joining us but this week I can honestly say the crazies have set in!!! OMG this is my 7th transfer and NO it does not get any easier!


 

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