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  1. #1
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    Default Thin Uterine Lining

    Hi Dr Jessup

    I suffer from a thin uterine lining issue due to the effects of radiation and chemotherapy.

    I was incredibly fortunate to find an egg donor which recently resulted in a successful egg pickup.

    I then went ahead and transferred 2 x 3 day old embryo's which unfortunately resulted in a BFN.

    As you can imagine I am extremely reluctant to keep going and "waste" my frozen embryo's on a thin lining so am hoping that you may be able to advise me.

    With my first transfer I was taking progynova, provera, progesterone pessaries and clexane injections but I have recently researched a pilot study completed which tested both Vitamin E and Viagra pessaries, it seemed to be very beneficial to women with thin linings.

    Any help would be most appreciated. Thank you.

  2. #2
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    Hi
    I would consider a hysteroscopy.
    Progynova and progesterone vaginally are standard HRT protocols and would seem fair. The value of Vitamen e may also be of benefit but viagra is dubious at best! why were you on clexane? Dr Glenn Sterling PS Blastocyst transfer is also the better option for you! Provera orally as well as progsterone vaginally???

  3. #3
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    Hi Dr Sterling

    Many thanks for your time and advice, it is most appreciated.

    I understood that I was on the Clexane injections to thin the blood so therefore increase blood flow to the uterine lining and therefore thicken it.

    I am a patient at a fertility clinic in Brisbane and last week had my follow up appointment with my fertility specialist after my first failed transfer. Since that appointment I am now following this medication:-

    - Progynova tablets (increasing by one every two days)
    - Nitro-Dor patches (worn for 12 hrs per day)
    - Clexane injections (1 per night)
    - Viagra pessaries (1 per night)
    - Aspirin (1 per day)
    - Vitamin E, Elevit
    - Acupuncture (Weekly)

    I am due back next week for an ulstrasound to see how the lining is going and I am expecting the doses to be increased. I have not been advised to do any further testing which I will ask about.

    I have tried to research information about Blastocysts transfers but am a little confused as the whole process is still quite new to me.

    Currently I have 8 frozen embryos - 4 which are graded as Excellent and 4 as Very Good. Can I use these current embryos to complete a blastocyst transfer or do I require another egg pick up?

    Unfortunately my husband has made it quite clear that he is not keen to do another pick up with my egg donor as he feels that she has helped us more than enough. Our donor was found through advertising with Bubhub and he feels that if we don't have success with the 8 we have that it is time to admit defeat.

    Thanks again for your time.

  4. #4
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    Good Luck with WDA. really top IVF expert. GS


 

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