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  1. #1
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    Default Managment of Prothrombin gene mutation

    Hi there,

    I was just interested in how you and your colleagues manage patients with known thrombophillias. Do you use clexane? or asprin? or both?

    I have prothrombin gene mutation.

    Also recently found I have MTHFR 677CT ( i know this one is controversial)

    I have had one missed miscarriage (heartbeat on 7 week scan slower and absent by 8 weeks) and possibly a subclinical pregnancy. I have a almost 3yo daughter conceived via IVF. I have never got pregnant naturally.

    Thanks for your advice

  2. #2
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    Default prothrombin gene mutation

    hi Pinkbutterfly,

    I would use both clexane and aspirin in conjuction with an IVF cycle in your case. There is a study running out of National Women's hospital(Auckland NZ) in conjucntion with a Scottish study which is looking at exactly your situation, and you may wish to contact the coordinator there ( a haematologist - Dr Clare McLintock) who would be able to give you the most up to date evidence avaliable.
    Hope this is of some help.
    Dr Jessup

  3. #3
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    Thank you so much for the info Dr Jessup, I will get in contact with Dr McLintock - sounds v,interesting. Thanks


 

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