Hi Dr Jessup, Thank you for assisting me with this question.
I have fallen pregnant naturally 3 times since 2007, 1st with my healthy daughter and then m/c at 15 weeks and then at 5 weeks. It has now been 12 months of TTC since then.
We had an autopsy done on 15 wk m/c which showed fine but no chromosome test was done (and I dont know why). A m/c this late concerns me.
We have had 3 natural IUIs and an IVF this year all resulting in negative. We got 10 blasts and our first natural FET is in a few weeks. A Laparoscopy showed clear in Nov 09.
As FS's like to see several m/cs before testing, I would like to be proactive in this area and get necessary autoimmune and neccessary testing now before money and time slips through our fingers. I would like to cover recurrent m/c and implantation failures.
I asked FS if I could have some tests and he gave me the following: Lupus Anticoaglent, ANF (what is this?), thrombophilia and one other. I really want to be thorough so do you think I should ask for the following tests to cover all areas?
Which ones should my husband be tested in?
- AntiNuclear Antibodies
PAI-1 levels and activity
Prothrombin II mutation
Protein C activity
Protein S activity
Factor V Leiden
Serum Immunoglobulins (IgG, IgM and IgA)
Thyroid levels (TSH, T3, T4)
MTHRR Gene Mutation
Urea Plasma DNA
TNF-a (TH1/TH2 Cytokines)
My FS gave me a blood test for NK Cells, but I see a biopsy on day 26-28 is the normal process. Can you please advise?
Cannot thank you enough for your help with this.