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  1. #1
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    Default mthfr

    just wondering your thoughts on mthfr as it is a controversial topic to doctors.

    i have concieved 3 times naturally all to miscarry between 4-12 weeks.
    we have concieved twice with ivf, the first was a chemical pegnancy and the second was a healthy baby boy.
    we used ivf for unexplained infertility but in my last cycle i asked to go onto clexane injections and it worked.
    it wasnt til halfway through my pregnancy that the hospital i was having antenatal care at diagnosed me with homozygous mthfr a1298c and my hubby with hetrozygous mthfr c677t. they then switched me from 40mg clexane to 100mg asprin until my son was born.

    we are now wanting to concieve baby #2 but want to avoid going down the ivf path again.

    heather

  2. #2
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    Default mthfr

    Hi Heatherm,

    You have conceived naturally before, so there is a good chance you can conceive again, and use aspirin and heparin/clexane from the time you first miss your period. If you were to do another cycle of IVF, have you seen a genetic counsellor and looked into the possibility of doing an IVF/PGD cycle where the embryos are specifically selected by those that don't carry a homozygous mthfr gene? Dr Sonya

  3. #3
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    no i havent seen a genetic counsellor but i have just moved states so i have to get a new referral to my ivf clinic. i am taking folic acid and mega b vitamins.
    if i do concieve naturally i may go onto the low does asprin.

    thankyou for your reply


 

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