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  1. #1
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    Default IVM (In Vitro Maturation) Have you had it?

    Hi ladies
    Doing a bit of research into IVM, whereby the eggs are collected at an immature stage from the ovaries and matured 'in vitro' before being fertilised. My basic synopsis, less drugs involved, shorter cycle but a more intricate collection process.

    I understand it has been particularly useful for those with PCOS and who suffer from OHSS in reducing the risk of overstimulation. What I am most interested in is it's use for those eggs collected at EPU which are not mature and are discarded. I have read on a US website they can even grow these excess immature eggs to blastocyst with IVM.

    As someone who gets a decent egg haul but has had more than half immature at my last 2 EPU's I am interested in anyone's experience with this? Perhaps the Perth ladies can help I have heard it was 'pioneered' there in Australia?

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    Hi Starf1sh, I can;t help you but I also researched IVM when I first started IVF. From memory, only one clinic in Perth does this in Australia. The scientist at my clinic says they don't do this at all, I am in Sydney.

  3. #3
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    Thanks K2Chat, I'm in Sydney too. Which clinic are you with that def doesn't do it? I'm with IVFA.

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    I am with Westmeand Fertility Center.

  5. #5
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    I had never heard of this until your post. After a bit of googling and reading, I'm a little bit sad at how many immature eggs we have had discarded over the years

    I hope this procedure becomes more widely used.

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    Hi Starfish,

    I have not done IVM yet, however at my last appoint with the FS a month ago, he recommended I have IVM next time I go to EPU. I currently have 4 frosties to use first, so Im crossing everything that I will be UTD before then.

    However, he recommended it for me as I have PCO. 1st IVF I had 21 eggs and overstimmed, and had a freeze all. 2nd IVF I had 18 eggs. Both times my oestrogen levels have been up around 30,000...and this is the main reason he recommends IVM for me. To get the eggs out before my levels skyrocket, and less chance of OHSS.

    He did say the procedure is a lot more technically challenging for the FS, and I will be in more pain afterwards. This is due to the follicles being so tiny and they apparently have a harder shell, making it more difficult to suck them out.

    Im at Fertility Specialists in Perth, and I believe there are only 2 FS that can do the procedure.

    Good luck!!

  7. #7
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    Thanks Gady for sharing your information, I knew the Perth girls would have some answers! Seems you guys on the west coast are way more progressive than us on this issue, haven't heard of any Sydney clinics doing this anyway. I intend to ask my FS at next opportunity.

    Pumperknickel, I too am sad we don't have this technology available to us, so many little immature eggies that never got a chance!

    Gady, I certainly hope you have a sticky little frosty coming your way very soon, but would also be interested in hearing the outcome of an IVM cycle from anyone who undergoes this, particularly what happens with the eggs collected, fert rates, blasto rates etc.
    Last edited by Starf1sh; 06-05-2010 at 15:32.

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    Default Ivm

    Hi Starf1sh,

    I have just joined and noticed your post from a few months ago. I have just finished my first round of IVM at the Fertilifty Specialists here in WA and am awaiting my results
    Let me know if you would still like any further information or advice about the whole IVM process.

    Good luck with your journey

  9. #9
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    Hi ladies
    I completed my first IVM cycle a few weeks ago but unfortunately nothing to transfer. How ever we did have one that nearly made it to the blast. Professor Roger Hart and I are very happy with the results. Just a quick update. It took me 11 ICSI/IVF cycles to conceive our darling boy. I had no problems with getting the eggs just blast numbers. We were recommended to proceed with IVM as its less invasive and can help with achieving better quality embryos that hopefully make the blast stage. I have been told though the sucess rate of embryos making the blast stage are a little lower than IVF/ICSI. What happens is you take purgeon for about 3 days and then a few days later you are in for egg collection. I was also told that you are in alot more pain than IVF. However I have to say that I had no pain after the procedure. The waiting game after the pickup to see if any make it to blast is a day longer due to the lab maturing the eggs over night before they introduce the sperm.
    Hope this makes sense

  10. #10
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    Hi may I ask how much does in vitro maturation cost? Where did you have it done? I did some research about the procedure and found out that IVM procedures are less expensive than traditional in vitro fertilization procedures. Correct me if I'm wrong because my friend who already had it done told me that. She didn't experience natural ovulation or regular menstrual cycles and her physician told her about IVM. Also I've read an article in a medical tourism website named placidway about the cost of IVM - "In the United States, the average cost of an IVM cycle ranges between $5,000 and $7,000, while traditional IVF procedures cost between $15,000 and $20,000 for a single cycle. In countries such as India, Mexico, Cyprus, Thailand, and Romania, costs are less, due to different healthcare delivery systems."


 

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