JohnC
25-03-2009, 07:56
There is nothing more persistent than a good scare campaign, and there are few things scarier in the popular imagination than cancer. It is therefore no surprise that the alleged link between penile cancer and being intact refuses to go away, despite the fact developed countries with majority circumcision rates (ie the US) have higher rates of this disease than those where infant circumcision is unknown. Though decisively falsified in this 1995 paper (http://www.pubmedcentral.nih.gov/pagerender.fcgi?artid=2543732&tool=pmcentrez&pageindex=1), the myth persists.
Rather than trawl over this tiresome historical debate, let's look instead at current Australian data and see what it tells us. A nine-year average (to June 2007) of annual hospital diagnoses of malignant genital cancer shows the following:
C61 Malignant neoplasm of prostate 18,719
C56 Malignant neoplasm of ovary 3,478
C54 Malignant neoplasm of corpus uteri 2,665
C53 Malignant neoplasm of cervix uteri 1,879
C62 Malignant neoplasm of testis 1,159
C51 Malignant neoplasm of vulva 595
C52 Malignant neoplasm of vagina 219
C60 Malignant neoplasm of penis 138
The argument usually ends there given the extreme rarity of this disease. But let's go further.
I have broken the averages for four cancers into 10-year cohorts and then mapped those against (male and female) population numbers to produce a rate per 100,000 (a standard epidemiolgical measure) for each cohort. Here's the result (http://farm4.static.flickr.com/3575/3382516487_40b7964a0d_b.jpg).
Some immediate observations come to mind:
1. Cervical cancer causes great concern not just because of larger numbers but because the disease burden falls disproportionately on younger women. A 30yo woman is twice as likely to contract cervical cancer than a 80yo man is penile cancer!
2. If one believed, against the evidence, that circumcision was a prophylactic then you would actually start with the vulva rather than the foreskin.
3. Both the vagina and the penis are very resilient, and carcinoma rates are only significant in the elderly, and then only marginally.
But let's go one step further. I did a broader data extract to find an incidence pattern among men similar to penile cancer. And indeed there is a cancer whose incidence is virtually identical - male breast cancer! Here are the two mapped against each other (http://farm4.static.flickr.com/3458/3383334070_a2b07b8e8a_b.jpg).
Now anyone who started talking about male chest hygiene :rolleyes:, nipple smegma :confused: or routine infant breast surgery :eek: would surely be considered somewhat unbalanced.
Conclusion: In a developed world setting, circumcision is irrelevant to that rare disease of elderly men, penile cancer.
=======================
Other posts in this "myths" series are:
Infection (http://www.bubhub.com.au/community/forums/showthread.php?t=241525)
AIDS/HIV (http://www.bubhub.com.au/community/forums/showthread.php?t=242912)
"Younger the better" (http://www.bubhub.com.au/community/forums/showthread.php?t=245680)
Rather than trawl over this tiresome historical debate, let's look instead at current Australian data and see what it tells us. A nine-year average (to June 2007) of annual hospital diagnoses of malignant genital cancer shows the following:
C61 Malignant neoplasm of prostate 18,719
C56 Malignant neoplasm of ovary 3,478
C54 Malignant neoplasm of corpus uteri 2,665
C53 Malignant neoplasm of cervix uteri 1,879
C62 Malignant neoplasm of testis 1,159
C51 Malignant neoplasm of vulva 595
C52 Malignant neoplasm of vagina 219
C60 Malignant neoplasm of penis 138
The argument usually ends there given the extreme rarity of this disease. But let's go further.
I have broken the averages for four cancers into 10-year cohorts and then mapped those against (male and female) population numbers to produce a rate per 100,000 (a standard epidemiolgical measure) for each cohort. Here's the result (http://farm4.static.flickr.com/3575/3382516487_40b7964a0d_b.jpg).
Some immediate observations come to mind:
1. Cervical cancer causes great concern not just because of larger numbers but because the disease burden falls disproportionately on younger women. A 30yo woman is twice as likely to contract cervical cancer than a 80yo man is penile cancer!
2. If one believed, against the evidence, that circumcision was a prophylactic then you would actually start with the vulva rather than the foreskin.
3. Both the vagina and the penis are very resilient, and carcinoma rates are only significant in the elderly, and then only marginally.
But let's go one step further. I did a broader data extract to find an incidence pattern among men similar to penile cancer. And indeed there is a cancer whose incidence is virtually identical - male breast cancer! Here are the two mapped against each other (http://farm4.static.flickr.com/3458/3383334070_a2b07b8e8a_b.jpg).
Now anyone who started talking about male chest hygiene :rolleyes:, nipple smegma :confused: or routine infant breast surgery :eek: would surely be considered somewhat unbalanced.
Conclusion: In a developed world setting, circumcision is irrelevant to that rare disease of elderly men, penile cancer.
=======================
Other posts in this "myths" series are:
Infection (http://www.bubhub.com.au/community/forums/showthread.php?t=241525)
AIDS/HIV (http://www.bubhub.com.au/community/forums/showthread.php?t=242912)
"Younger the better" (http://www.bubhub.com.au/community/forums/showthread.php?t=245680)