SPC
05-05-2008, 08:11
So, it's been shown that folic acid supplements reduce risk of neural tube defects, premature labour and some childhood cancers and now for more good news:
"NEW YORK (Reuters Health) May 01 - Use of folic acid and other vitamin supplements before or during pregnancy appears to reduce the risk of placental abruption, Norwegian researchers report in the April issue of the American Journal of Epidemiology.
Dr. Roy M. Nilsen of the University of Bergen and colleagues studied data on more than 280,000 singleton deliveries recorded in Norway between 1999 and 2004. In total, there were 1070 placental abruptions (0.38%).
Use of folic acid with or without multivitamin supplements before or during pregnancy was reported by 36.4% of those who had abruptions and 44.4% of those who did not.
Compared to no use, any supplement use gave an adjusted odds ratio for abruption of 0.74. For folic acid use alone, the odds ratio was 0.81, and for multivitamin use it was 0.72. The greatest effect was seen in those who had used both types of supplements (adjusted odds ratio, 0.68).
Should such an effect be proven in interventional studies, Dr. Nilsen commented to Reuters Health, "this would extend current recommendations to assure adequate intake of folate before and early in pregnancy to prevent neural tube defects.""
"NEW YORK (Reuters Health) May 01 - Use of folic acid and other vitamin supplements before or during pregnancy appears to reduce the risk of placental abruption, Norwegian researchers report in the April issue of the American Journal of Epidemiology.
Dr. Roy M. Nilsen of the University of Bergen and colleagues studied data on more than 280,000 singleton deliveries recorded in Norway between 1999 and 2004. In total, there were 1070 placental abruptions (0.38%).
Use of folic acid with or without multivitamin supplements before or during pregnancy was reported by 36.4% of those who had abruptions and 44.4% of those who did not.
Compared to no use, any supplement use gave an adjusted odds ratio for abruption of 0.74. For folic acid use alone, the odds ratio was 0.81, and for multivitamin use it was 0.72. The greatest effect was seen in those who had used both types of supplements (adjusted odds ratio, 0.68).
Should such an effect be proven in interventional studies, Dr. Nilsen commented to Reuters Health, "this would extend current recommendations to assure adequate intake of folate before and early in pregnancy to prevent neural tube defects.""